本文選題：抑郁癥　切入點(diǎn)：圍絕經(jīng)期　出處：《中國(guó)中醫(yī)基礎(chǔ)醫(yī)學(xué)雜志》2014年09期

【摘要】：目的:觀察四二五合方合甘麥大棗湯治療圍絕經(jīng)期抑郁癥的臨床療效。方法:將40例圍絕經(jīng)期抑郁癥患者按隨機(jī)數(shù)字表法分為治療組和對(duì)照組各20例。對(duì)照組用雌激素治療,治療組在對(duì)照組的基礎(chǔ)上加用中藥四二五合方合甘麥大棗湯治療,觀察2組臨床療效,對(duì)比治療前后改良Kupperman、HAMD抑郁量表評(píng)分及FSH、LH、E2水平。結(jié)果:治療組臨床療效總有效率為90%,對(duì)照組為75%,治療組明顯優(yōu)于對(duì)照組(P0.05)。治療組改良Kupperman及HAMD抑郁量表評(píng)分減分率顯著高于對(duì)照組(P0.05),E2水平升高明顯高于對(duì)照組(P0.05)。結(jié)論:四二五合方合甘麥大棗湯治療圍絕經(jīng)期抑郁癥療效確切。
[Abstract]:Objective: to observe the clinical curative effect of the treatment of peri-menopausal depression with the combination of four twenty-five prescriptions and Ganmai Dazao decoction. Methods: forty patients with postmenopausal depression were randomly divided into two groups: treatment group (n = 20) and control group (n = 20), and control group (n = 20) treated with estrogen. On the basis of the control group, the treatment group was treated with the combination of traditional Chinese medicine four twenty-five formula and Ganmai Dazao decoction, and the clinical efficacy of the two groups was observed. Results: the total effective rate was 90 in the treatment group and 75 in the control group. The score of modified Kupperman and HAMD depression scale in the treatment group was significantly better than that in the control group (P 0.05). The scores of modified Kupperman and HAMD depression scale in the treatment group were significantly lower than those in the control group. The level of E _ 2 was significantly higher than that of control group (P 0.05). Conclusion: it is effective to treat perimenopausal depression with the combination of four Erwu decoction and Ganmai Dazao decoction.
【作者單位】： 南陽理工學(xué)院張仲景國(guó)醫(yī)學(xué)院;南陽理工學(xué)院附屬醫(yī)院;
【分類號(hào)】：R749.4

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