本文選題：柴胡龍骨牡蠣湯　切入點(diǎn)：抗焦慮抑郁藥物　出處：《中華中醫(yī)藥學(xué)刊》2017年03期

【摘要】：目的:研究柴胡龍骨牡蠣湯加減結(jié)合抗焦慮抑郁藥物對(duì)軀體化焦慮、抑郁狀態(tài)的療效及機(jī)制分析。方法:選取2015年8月—2016年8月接診的300例軀體化抑郁焦慮患者作為本次研究對(duì)象。按隨機(jī)數(shù)表法分為觀察組和對(duì)照組,各150例,對(duì)照組采用抗焦慮抑郁藥物進(jìn)行治療,觀察組柴胡龍骨牡蠣湯加減結(jié)合抗焦慮抑郁藥物進(jìn)行治療,觀察兩組患者治療前后SAS、SDS評(píng)分,治療后郁病中醫(yī)癥狀積分(失眠、心悸心慌、肢體怕冷、肢體倦怠、肢體疼痛),治療療效情況。結(jié)果:兩組患者治療前SAS、SDS評(píng)分無(wú)明顯差異(61.27±9.28、63.28±9.37)分比(60.38±8.30、62.92±7.82)分(P0.05),治療后,觀察組SAS、SDS評(píng)分均小于對(duì)照組(36.70±6.39、38.92±7.81)分比(42.32±7.20、44.38±6.29)分(P0.05);觀察組失眠、心悸心慌、肢體怕冷、肢體倦怠、肢體疼痛均小于對(duì)照組(2.87±1.01、2.23±0.71、2.08±0.56、1.26±0.32、2.39±0.67)分比(3.28±1.03、2.79±0.80、2.97±0.73、2.01±0.60、4.02±1.23)分(P0.05);觀察組總有效率優(yōu)于對(duì)照組93.33%(140/150)比72.00%(108/150)(P0.05)。結(jié)論:柴胡龍骨牡蠣湯加減結(jié)合抗焦慮抑郁藥物對(duì)軀體化焦慮、抑郁狀態(tài)的療效及機(jī)制。
[Abstract]:Objective: to study the somatic anxiety of Bupleurum Longgu Oyster decoction combined with antianxiety and depression drugs. Methods: 300 patients with somatic depression and anxiety were selected from August 2015 to August 2016. The control group was treated with anti-anxiety and depressant drugs, the observation group was treated with Chaihu Longgu oyster decoction combined with anti-anxiety and depressant drugs, the scores of SASS-SDS before and after treatment were observed, and the TCM symptom score of depression (insomnia, palpitations and palpitations) after treatment were observed. Results: there was no significant difference in SDS scores between the two groups before treatment (61.27 鹵9.28 鹵63.28 鹵9.37) vs 60.38 鹵8.30 鹵62.92 鹵7.82) (P 0.05). After treatment, the scores of SASSDS in the observation group were lower than those in the control group (36.70 鹵6.39 鹵38.92 鹵7.81) vs 42.32 鹵7.204.38 鹵6.29 (P 0.05). The scores of palpitation, limb dread of cold, limb burnout and limb pain were lower than those of the control group (2.87 鹵1.01g 2.23 鹵0.71U 2.08 鹵0.56U 1.26 鹵0.322.39 鹵0.67), compared with 3.28 鹵1.030.32.79 鹵0.800.32.79 鹵0.7804.01 鹵0.604.02 鹵1.23), the total effective rate of the observation group was better than that of the control group 93.3333140- 150) than that of the control group (72.000.108n-1 / 150). Conclusion: Chaihu Longgu Oyster decoction can reduce the somatic anxiety combined with anti-anxiety depressant drug, and the total effective rate of the observation group is better than that of the control group (93.3333140P / 150), and the total effective rate of the observation group is better than that of the control group (P 0.05). The therapeutic effect and mechanism of depression.
【作者單位】： 諸暨市人民醫(yī)院;
【分類號(hào)】：R749

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