本文選題：老年癡呆癥　切入點(diǎn)：HVLT　出處：《陜西師范大學(xué)》2012年碩士論文　論文類型：學(xué)位論文

【摘要】：目標(biāo)結(jié)合使用霍普金斯口頭學(xué)習(xí)測(cè)試(HVLT)和簡(jiǎn)易精神狀態(tài)檢查量表(MMSE),調(diào)查特定的量表分界值是否適用于跨文化情境中來(lái)自不同種族老年人的輕度癡呆篩查試驗(yàn),以及調(diào)查他們的表現(xiàn)是否受到人口統(tǒng)計(jì)變量如年齡、性別和教育的影響。 方法使用橫向研究設(shè)計(jì),采用訪問(wèn)健康中心、護(hù)理院,及上門調(diào)查的抽樣技術(shù)從雅加達(dá)城市地區(qū)征集217名來(lái)自于混合種族的老年人(爪哇(n=141)、蘇丹(n=51)和中國(guó)(n=25))參與調(diào)查。 使用方差分析評(píng)估人口統(tǒng)計(jì)變量(年齡、性別、受教育程度和族裔)與HVLT和MMSE得分之間的關(guān)系。采用邏輯回歸調(diào)查HVLT和MMSE特定分界值與年齡、性別、教育、種族及癡呆診斷的相關(guān)關(guān)系。采用線性回歸分析人口因素(年齡、性別、受教育程度以及族裔)對(duì)參與者HVLT及MMSE表現(xiàn)的解釋和預(yù)測(cè)。 結(jié)果種族差異在HVLT回憶表現(xiàn)中呈非顯著性水平(延遲記憶(DR)p=0.65；瞬時(shí)記憶(IR)p=0.43)。然而在經(jīng)過(guò)對(duì)參與者年齡(p0.001)及受教育水平(p0.001)數(shù)據(jù)矯正后,MMSE得分呈現(xiàn)顯著的種族差異,但是這一差異的原因已被中國(guó)裔參與者的平均較高的年齡以及小樣本容量解釋。此外,雖然性別未在MMSE得分中顯現(xiàn)顯著差異(p=0.21),教育水平和性別之間卻表現(xiàn)出強(qiáng)烈的交互作用(p=0.04)。這或許暗示了在低教育族群(從未接受過(guò)正式教育)中,女性的MMSE表現(xiàn)比男性更好。但是,在得分低于分界值(存在患老年癡呆癥的風(fēng)險(xiǎn))的參與者種族中,種族和性別并不具備很好的預(yù)測(cè)效果,而參與者的年齡和受教育水平在老年癡呆癥的預(yù)測(cè)中起了最為關(guān)鍵的作用。 結(jié)論年齡、性別和教育水平是老人在MMSE中表現(xiàn)的顯著預(yù)測(cè)指標(biāo)。作為一種適用于不同種族的輕度癡呆癥篩查工具及老年性癡呆/阿爾茨海默癥(Alzheimer's Disease,AD)臨床診斷的一部分,建議將HVLT和MMSE組合適用以獲得更高的敏感度和特異度。然而,考慮到不同文化背景的限制,此工具需要進(jìn)一步校訂以適應(yīng)中國(guó)人口老齡化的趨勢(shì)及受教育程度普遍較低的現(xiàn)狀。
[Abstract]:Objective to investigate whether the specific threshold values were applicable to mild dementia screening trials in cross-cultural settings in elderly people of different races, using the Hopkins Oral Learning Test (HVLTT) and the MMSEI Mental State Test (MMSEN), a combination of the Hopkins Oral Learning Test (HST) and the simple Mental State Test (MMSE). And investigate whether their performance is affected by demographic variables such as age, sex, and education. Methods A cross-sectional study design was used to collect 217 elderly people from the urban areas of Jakarta by visiting health centers, nursing homes, and door-to-door surveys. ANOVA was used to assess the relationship between demographic variables (age, sex, educational attainment and ethnicity) and HVLT and MMSE scores. Correlation between race and dementia diagnosis. Linear regression analysis was used to analyze and predict the HVLT and MMSE performance of participants by using population factors (age, sex, education and ethnicity). Results ethnic differences were not significant in HVLT memory (delayed memory 0.65; transient memory 0.43). However, there were significant racial differences after correction of age and educational level (p 0.001). But the difference has been explained by the average age of Chinese participants and the size of small samples. Although gender did not show significant differences in MMSE scores, there was a strong interaction between education level and gender. This may suggest that in lower-education groups (never received formal education), Women performed better on MMSE than men. However, race and gender did not have a good predictive effect in participants who scored below the threshold (there was a risk of Alzheimer's disease). The age and level of education played a key role in predicting Alzheimer's disease. Conclusion Age, sex and education level are significant predictors of MMSE in the elderly. It is a part of the clinical diagnosis of Alzheimer's disease and Alzheimer's disease as a screening tool for mild dementia in different races and Alzheimer's disease. It is suggested that the combination of HVLT and MMSE be applied to obtain higher sensitivity and specificity. However, in view of the limitations of different cultural backgrounds, this tool needs to be further revised to adapt to the trend of aging population in China and the current situation of generally low education level.
【學(xué)位授予單位】：陜西師范大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R749.1

【參考文獻(xiàn)】

相關(guān)期刊論文 前8條

1 張艷霞;;輕度認(rèn)知功能障礙的篩查工具評(píng)價(jià)[J];中國(guó)老年保健醫(yī)學(xué);2009年05期

2 景秀絨 ,李玲梅 ,周燕;老年性癡呆癥病人的家庭護(hù)理[J];護(hù)理研究;2002年04期

3 肖世富;神經(jīng)心理測(cè)驗(yàn)和評(píng)定量表在阿爾茨海默病的應(yīng)用及價(jià)值[J];中國(guó)現(xiàn)代神經(jīng)疾病雜志;2005年03期

4 張景華,王魯寧,何祥;中老年非癡呆患者海馬區(qū)阿爾茨海默樣病理改變的分析[J];中華老年醫(yī)學(xué)雜志;2003年03期

5 肖世富;薛海波;李冠軍;李春波;吳文源;張明園;;老年輕度認(rèn)知功能損害的隨訪研究[J];中華醫(yī)學(xué)雜志;2006年21期

6 尹宗寧;中醫(yī)藥防治老年癡呆癥的研究進(jìn)展[J];中國(guó)老年學(xué)雜志;2005年03期

7 劉園園;王濤;李霞;李冠軍;蘇寧;肖世富;;中文版成套神經(jīng)心理測(cè)驗(yàn)的信度和效度研究[J];中華臨床醫(yī)師雜志(電子版);2011年05期

8 劉園園;肖世富;王濤;李霞;李冠軍;蘇寧;;中文版成套神經(jīng)心理測(cè)驗(yàn)診斷輕度認(rèn)知損害的臨床應(yīng)用[J];中華臨床醫(yī)師雜志(電子版);2011年09期

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