精神分裂癥影響因素的病例對照研究
本文選題:精神分裂癥 切入點:影響因素 出處:《蘇州大學》2013年碩士論文 論文類型:學位論文
【摘要】:目的 了解蘇州市吳江區(qū)震澤鎮(zhèn)轄區(qū)內的精神分裂癥的主要影響因素,為進一步探討精神分裂癥病因和制定應對精神分裂癥的策略和措施提供依據(jù)。 方法 以蘇州市吳江區(qū)震澤鎮(zhèn)轄區(qū)2012年管理全部249例精神分裂癥患者為病例組,以按性別、年齡(±5歲)、居住地(同一居委會)進行1:1匹配的非精神疾病病人為對照組,對13項精神分裂癥的可疑影響因素等,進行回顧性問卷調查。 本次調查由研究者一人負責,調查對象病例組為患者的監(jiān)護人、對照組由患者本人。 經(jīng)當場和當天審核合格所獲得資料采用EpiData3.1軟件“雙人雙次錄入并進行邏輯糾錯”的方法進行數(shù)據(jù)庫建立和SPSS20.0統(tǒng)計軟件采用單因素條件Logistic回歸分析方法和多因素條件Logistic回歸分析后退法進行統(tǒng)計分析。 結果 249對配對資料無一剔除,全部合格。病例組與對照組在性別、年齡、居住地方面無統(tǒng)計學差異(P0.05)。病例組和對照組重復調查符合率無統(tǒng)計學差異(P0.05) 單因素分析結果表明,有精神病家族史(OR=6.257)、性格內向(OR=5.506)、不恰當情緒宣泄(OR=3.476)、遭遇精神創(chuàng)傷事件(OR=3.435)、無知心朋友(OR=3.354)、單身(OR=2.784)、幼年不良遭遇(OR=2.658)、文化程度低(OR=2.625)、家庭成員關系對抗(OR=2.363)可能是精神分裂癥促進因素;而成年前父母非在婚(OR=1.052)、不與家人共同居。∣R=1.198)、家庭經(jīng)濟狀況(OR=1.283)、有顱腦疾病史(OR=1.675)可能是精神分裂癥的無關因素。 多因素分析結果表明,,有精神病家族史(OR=4.623)、遭遇精神創(chuàng)傷事件(OR=3.435)、無知心朋友(OR=3.096)、性格內向(OR=2.752)、不恰當情緒宣泄(OR=1.771)可能是促進因素。 結論 1、精神病家族史陽性、遭遇精神創(chuàng)傷事件、人際關系不良、不善情緒宣泄、性格內向等內外環(huán)境因素可能是蘇州市吳江區(qū)震澤鎮(zhèn)精神分裂癥的主要促進因素。應將具有這些特征的人群作為精神分裂癥的高危人群進行預防。 2、幼年不良遭遇、家庭成員關系對抗、文化程度低、單身等內外環(huán)境因素與精神分裂癥是否是蘇州市吳江區(qū)震澤鎮(zhèn)精神分裂癥可能的促進因素有待于進一步研究證實。 3、家庭經(jīng)濟狀況、共同居住者、顱腦疾病史可能與蘇州市吳江區(qū)震澤鎮(zhèn)精神分裂癥無關。
[Abstract]:Purpose. To understand the main influencing factors of schizophrenia in Zhenze Town, Wu Jiang District, Suzhou City, and to provide the basis for further discussion on the etiology of schizophrenia and the formulation of strategies and measures to deal with it. Method. In 2012, all 249 schizophrenic patients in Zhenze Town District, Wu Jiang District, Suzhou were taken as the case group, and 1: 1 matched non-mental disease patients who were matched by sex, age (鹵5 years old) and residence (the same neighborhood committee) were taken as the control group. A retrospective questionnaire survey was conducted on 13 suspected factors affecting schizophrenia. The patient group was the guardian of the patient and the control group was the patient himself. The data obtained after the spot and on the day examination were established by the method of EpiData3.1 software "double entry and logical error correction" and the single factor conditional Logistic regression analysis method and multiple factors were used in the SPSS20.0 statistical software. The regression analysis of conditional Logistic regression was carried out. Results. There was no significant difference in sex, age and residence between the case group and the control group (P 0.05). There was no significant difference in the coincidence rate of repeated investigation between the case group and the control group (P 0.05). The results of single factor analysis show that, The family history of mental illness is 6.257, the personality is introverted, OR5.506, the inappropriate emotional catharsis is 3.476, the mental trauma event is 3.435, no close friend is OR3.354, the single person is 2.784, the education level is lower than OR2.625, the family member relationship is antagonistic to OR2.363) may be the promoting factor of schizophrenia. Before adulthood, parents were not married at OR1. 052, did not live with their families, and their economic status was 1.283. History of craniocerebral disease was 1. 675) and may be an unrelated factor for schizophrenia. The results of multivariate analysis showed that the family history of mental illness was 4.623, the occurrence of mental trauma was 3.435, no intimate friend was 3.096, and the personality was introverted, and the inappropriate emotional catharsis was OR1.771). Conclusion. 1. Positive family history of mental illness, traumatic events, poor interpersonal relationships, and poor emotional release. Introversion and other internal and external environmental factors may be the main promoting factors of schizophrenia in Zhenze Town, Wu Jiang District, Suzhou City. The population with these characteristics should be regarded as the high risk group of schizophrenia. 2.The adverse experiences of childhood, family relationship confrontation, low level of education, singleness and so on, and whether schizophrenia is the possible promoting factor of schizophrenia in Zhenze Town, Wu Jiang District of Suzhou should be further studied and verified. 3. Family economic status, cohabitation, history of craniocerebral disease may have nothing to do with schizophrenia in Zhenze Town, Wu Jiang District, Suzhou City.
【學位授予單位】:蘇州大學
【學位級別】:碩士
【學位授予年份】:2013
【分類號】:R749.3
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