本文選題：廣泛性焦慮障礙　切入點(diǎn)：生活質(zhì)量　出處：《復(fù)旦大學(xué)》2013年碩士論文　論文類型：學(xué)位論文

【摘要】：目的評(píng)估社區(qū)廣泛性焦慮障礙(Generalized anxiety disorder, GAD)患者的生活質(zhì)量并對(duì)其相關(guān)因素進(jìn)行分析,了解患者生理和心理的綜合信息,以幫助醫(yī)務(wù)人員在臨床診療過(guò)程中綜合評(píng)價(jià)患者的生命質(zhì)量。 方法本研究于2009年1月至2011年10月進(jìn)行。研究對(duì)象來(lái)源于上海市6個(gè)社區(qū)衛(wèi)生服務(wù)中心就診人群,共納入GAD患者94人。采用生活質(zhì)量簡(jiǎn)表-36(The MOS36-item short-form health survey,SF-36)對(duì)GAD患者進(jìn)行生活質(zhì)量評(píng)估。SF-36量表包括軀體健康(Physical health of SF-36, PH)和精神健康(Mental health of SF-36,MH)兩部分。PH由總體健康(General Health, GH)、生理功能(Physical Function,PF)、軀體疼痛(Bodily Pain, BP)及軀體健康所致的角色限制(Role-Physical, RP)四個(gè)維度綜合而成,MH由生命活力(Vitality, VT)、社交功能(Social Function, SF)、心理健康(Mental Health, MH)及情感問(wèn)題所致的角色限制(Role-Emotional, RE)四個(gè)維度綜合而成。采用王紅妹等對(duì)杭州市區(qū)居民生命質(zhì)量研究的SF-36各維度的分值作為我們研究的對(duì)照常模。采用廣泛性焦慮量表(A7-item anxiety scale,GAD-7)、漢密爾頓焦慮量表(Hamilton anxiety rating scale, HAM A)評(píng)價(jià)患者的焦慮狀態(tài),漢密爾頓抑郁量表(Hamilton depression rating scale, HAMD)評(píng)價(jià)患者的抑郁狀態(tài),并研究SF-36與GAD-7、HAMA的相關(guān)性。 結(jié)果 1.主要指標(biāo)結(jié)果：本研究的結(jié)果顯示社區(qū)GAD患者GH、PF、BP、RP、RE、 SF、VT、MH八個(gè)維度的分值分別為：13.29±39.14、73.67±22.13、72.44±21.56、32.98±37.25、35.82±38.87、59.57±22.33、49.41±16.94、46.30±16.08。 將GAD患者的生命質(zhì)量與常模進(jìn)行比較,除VT這一項(xiàng)外,GAD患者GH、PF、BP、RP、RE、SF、MH七個(gè)維度的評(píng)分均低于常模,差異有統(tǒng)計(jì)學(xué)意義(P0.01)。 2.次要指標(biāo)結(jié)果： (1)GAD患者SF-36量表各維度分?jǐn)?shù)按性別進(jìn)行了比較,女性PF低于男性,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。 (2)將HAMD以17分為界分為兩組：伴有抑郁狀態(tài)的患者與不伴抑郁狀態(tài)的患者。其SF-36八個(gè)維度之間的差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。有抑郁癥狀患者的HAMA得分高于不伴抑郁癥狀的患者,差異有統(tǒng)計(jì)學(xué)意義(P=0.02)。 (3)GAD-7評(píng)分與SF-36總分之間的Pearson相關(guān)系數(shù)為-0.257(P=0.006),呈負(fù)相關(guān)。 (4) HAMA總分與5F-36總分之間Pearson相關(guān)系數(shù)為-0.083(P=0.214),沒(méi)有相關(guān)性。 (5)計(jì)算HAMA,總分、精神焦慮因子、軀體焦慮因子與SF-36八個(gè)維度的Pearson相關(guān)系數(shù),發(fā)現(xiàn)只有軀體焦慮因子與軀體健康所致的角色限制呈負(fù)相關(guān),Pearson相關(guān)系數(shù)為-0.255(p0.05)。 (6)計(jì)算HAMA總分、精神焦慮因子、軀體焦慮因子與5F-36軀體健康、精神健康的Pearson相關(guān)系數(shù),其中軀體焦慮因子與軀體健康呈負(fù)相關(guān), Pearson相關(guān)系數(shù)為-0.252(p0.05)。 結(jié)論社區(qū)GAD患者的生命質(zhì)量受損。在社區(qū)GAD患者的診治過(guò)程中,可考慮予以患者生活質(zhì)量的評(píng)估,在治療的同時(shí),促進(jìn)患者生命質(zhì)量的改善。
[Abstract]:Objective to evaluate the quality of life (QOL) of patients with generalized anxiety disorder (GAD) in community, and to analyze the related factors, and to understand the comprehensive information of the patients' physiology and psychology. In order to help the medical staff in the clinical diagnosis and treatment process comprehensive evaluation of the quality of life of patients. Methods the study was conducted from January 2009 to October 2011. The subjects were from 6 community health service centers in Shanghai. A total of 94 GAD patients were included. The MOS36-item short-form health survey (SF-36) was used to assess the quality of life of GAD patients. The SF-36 scale included physical health of physical health of SF-36 and mental health of SF-36. The four dimensions of physical function, physical function, physical pain, Bodily Painand the role restriction caused by physical health are combined to form MH: vital Vitality, VTN, Social function, SFU, Mental Health and Mental Health, MHH) and role restriction caused by emotional problems. Four dimensions were synthesized. The scores of SF-36 dimensions in the quality of life study of Hangzhou urban residents by Wang Hongmei et al were taken as the control norm of our study. The generalized anxiety scale A7-item anxiety scaleGAD-7A and Hamilton anxiety were used to study the quality of life of urban residents in Hangzhou city by using the generalized anxiety scale (A7-item anxiety scale) and the Hamilton anxiety scale (Hamilton anxiety scale). Rating scale (HAM A) was used to evaluate the anxiety state of the patients. Hamilton depression rating scale (Hamd) was used to evaluate depression and to study the correlation between SF-36 and GAD-7 Hama. Results. 1. Main outcome measures: the results of this study showed that the scores of the eight dimensions of GAD patients in community were respectively 13.29 鹵39.14 鹵73.67 鹵21.562.98 鹵37.2579.57 鹵22.39.59.57 鹵22.39.41 鹵16.94n 46.30 鹵16.088.The results showed that the scores of the eight dimensions of GAD patients in community were respectively 13.29 鹵39.14 鹵73.67 鹵21.562.98 鹵37.87.59.57 鹵22.331,49.41 鹵16.94n 46.30 鹵16.08. The quality of life (QOL) of patients with GAD was compared with that of norm. Except for VT, the scores of seven dimensions of GAD patients were lower than those of norm, and the difference was statistically significant (P 0.01). 2. Secondary indicator outcomes:. The scores of each dimension of SF-36 scale in patients with GAD were compared according to sex. The PF of female was lower than that of male, and the difference was statistically significant (P 0.05). (2) HAMD was divided into two groups according to 17: patients with depression and those without depression. There was no significant difference in the eight dimensions of SF-36. The HAMA score of patients with depressive symptoms was higher than that of patients without depressive symptoms. The difference was statistically significant. The Pearson correlation coefficient between GAD-7 score and total SF-36 score was -0.257 and 0.006, which was negatively correlated. The Pearson correlation coefficient between the total score of HAMA and the total score of 5F-36 was -0.083 and 0.214g respectively, and there was no correlation between the total score of HAMA and the total score of 5F-36. The total score, mental anxiety factor, somatic anxiety factor and Pearson correlation coefficient of the eight dimensions of SF-36 were calculated. It was found that only somatic anxiety factor was negatively correlated with the role restriction caused by physical health, and the Pearson correlation coefficient was -0.255% (p 0.05). The total score of HAMA, mental anxiety factor, somatic anxiety factor and Pearson correlation coefficient of 5F-36 physical health and mental health were calculated. There was a negative correlation between somatic anxiety factor and physical health, and Pearson correlation coefficient was -0.252 (p 0.05). Conclusion the quality of life of GAD patients in the community is impaired. In the course of diagnosis and treatment of GAD patients in the community, the evaluation of the quality of life of the patients can be considered to promote the improvement of the quality of life of the patients with GAD at the same time of treatment.
【學(xué)位授予單位】：復(fù)旦大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2013
【分類號(hào)】：R749.7

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 高新立;;中西醫(yī)結(jié)合治療廣泛性焦慮障礙60例[J];中醫(yī)研究;2012年09期

2 付翠;元認(rèn)知模型:廣泛性焦慮障礙研究中的新理念[J];醫(yī)學(xué)與哲學(xué);2001年12期

3 袁勇貴,吳瑞枝;老年期廣泛性焦慮障礙[J];中國(guó)民政醫(yī)學(xué)雜志;2002年01期

4 張順泉,張海生,謝健;廣泛性焦慮障礙的臨床治療[J];中國(guó)心理衛(wèi)生雜志;2004年06期

5 楊瑞玲;吳成翰;;廣泛性焦慮障礙的中西醫(yī)治療[J];現(xiàn)代中西醫(yī)結(jié)合雜志;2006年04期

6 李恒芬;曹素霞;朱性霞;馬建東;謝光榮;;廣泛性焦慮障礙的個(gè)性心理特征[J];中國(guó)神經(jīng)精神疾病雜志;2007年06期

7 韓雪;;廣泛性焦慮障礙的元認(rèn)知理論[J];四川精神衛(wèi)生;2008年01期

8 蘇秀茹;盧淑蘭;栗克清;李喜潑;;保定市廣泛性焦慮障礙的流行病學(xué)調(diào)查[J];神經(jīng)疾病與精神衛(wèi)生;2008年05期

9 錢(qián)敏才;沈鑫華;鈕富榮;楊劍虹;林敏;李良;;首發(fā)廣泛性焦慮障礙患者生活事件社會(huì)支持個(gè)性特征研究[J];實(shí)用醫(yī)學(xué)雜志;2009年03期

10 王金風(fēng);;一例廣泛性焦慮障礙的案例報(bào)告[J];社會(huì)心理科學(xué);2010年04期

相關(guān)會(huì)議論文 前10條

1 沈鑫華;錢(qián)敏才;鈕富榮;孫松濤;朱毅平;楊劍虹;林敏;俞柏潤(rùn);李良;;首發(fā)廣泛性焦慮障礙患者6種神經(jīng)化學(xué)物質(zhì)濃度的初步觀察[A];2009年浙江省醫(yī)學(xué)會(huì)精神病學(xué)學(xué)術(shù)年會(huì)暨浙江省醫(yī)師協(xié)會(huì)精神科醫(yī)師分會(huì)第二屆年會(huì)論文匯編[C];2009年

2 沈鑫華;錢(qián)敏才;鈕富榮;孫松濤;朱毅平;楊劍虹;林敏;俞柏潤(rùn);李良;沈仲夏;;首發(fā)廣泛性焦慮障礙患者血漿腦源性神經(jīng)營(yíng)養(yǎng)因子水平的動(dòng)態(tài)觀察[A];2011年浙江省心理衛(wèi)生協(xié)會(huì)第九屆學(xué)術(shù)年會(huì)論文匯編[C];2011年

3 黃悅勤;李恒;劉肇瑞;張婷婷;李占江;韓海英;魏鏡;史麗麗;唐牟尼;陳曉瑩;;認(rèn)知行為治療聯(lián)合藥物治療廣泛性焦慮障礙的隨機(jī)單盲對(duì)照試驗(yàn)[A];中華醫(yī)學(xué)會(huì)第十次全國(guó)精神醫(yī)學(xué)學(xué)術(shù)會(huì)議論文匯編[C];2012年

4 徐蕊;封春亮;古若雷;黃瑞旺;楊秋莉;羅躍嘉;;廣泛性焦慮障礙情緒記憶回避機(jī)制的腦成像研究[A];心理學(xué)與創(chuàng)新能力提升——第十六屆全國(guó)心理學(xué)學(xué)術(shù)會(huì)議論文集[C];2013年

5 金瓊;;一例廣泛性焦慮障礙患者的心理動(dòng)力學(xué)治療案例[A];2013浙江省醫(yī)學(xué)會(huì)精神病學(xué)分會(huì)學(xué)術(shù)年會(huì)暨浙江省醫(yī)師協(xié)會(huì)精神科醫(yī)師分會(huì)第六屆年會(huì)論文匯編[C];2013年

6 張燕;李凌江;劉軍;賀忠;單寶慈;;首發(fā)廣泛性焦慮障礙患者腦白質(zhì)的彌散張量成像研究[A];Proceedings of the 8th Biennial Conference of the Chinese Society for Neuroscience[C];2009年

7 趙杰;;溫陽(yáng)法治療廣泛性焦慮障礙的探討[A];中國(guó)中西醫(yī)結(jié)合學(xué)會(huì)精神疾病專業(yè)委員會(huì)第十一屆學(xué)術(shù)年會(huì)論文匯編[C];2012年

8 姚淑敏;李占江;韓海英;熊紅芳;李平;;廣泛性焦慮障礙認(rèn)知行為治療聯(lián)合藥物治療與單純藥物治療的對(duì)照研究[A];中華醫(yī)學(xué)會(huì)精神病學(xué)分會(huì)第九次全國(guó)學(xué)術(shù)會(huì)議論文集[C];2011年

9 吳偉林;王超英;;九味鎮(zhèn)心顆粒與舍曲林治療廣泛性焦慮障礙的臨床觀察[A];中國(guó)中西醫(yī)結(jié)合學(xué)會(huì)精神疾病專業(yè)委員會(huì)第十一屆學(xué)術(shù)年會(huì)論文匯編[C];2012年

10 孫達(dá)亮;華逢春;蔡亦蘊(yùn);施慎遜;管一暉;;廣泛性焦慮障礙患者腦糖代謝變化的PET顯像初步研究[A];中華醫(yī)學(xué)會(huì)第十次全國(guó)精神醫(yī)學(xué)學(xué)術(shù)會(huì)議論文匯編[C];2012年

相關(guān)重要報(bào)紙文章 前1條

1 上海長(zhǎng)海醫(yī)院神經(jīng)內(nèi)科 張萍;廣泛性焦慮障礙的自我診斷與治療[N];上海中醫(yī)藥報(bào);2010年

相關(guān)博士學(xué)位論文 前1條

1 廖梅;青少年廣泛性焦慮障礙患者腦結(jié)構(gòu)與腦功能特點(diǎn)的研究[D];中南大學(xué);2013年

相關(guān)碩士學(xué)位論文 前10條

1 王亞博;廣泛性焦慮障礙患者聽(tīng)覺(jué)威脅信息前注意加工的事件相關(guān)電位研究[D];大連醫(yī)科大學(xué);2013年

2 趙靜囡;東西方視野下的廣泛性焦慮障礙[D];黑龍江中醫(yī)藥大學(xué);2013年

3 周田田;廣泛性焦慮障礙病人心理健康狀況、人格特征及血漿皮質(zhì)醇水平的相關(guān)研究[D];青島大學(xué);2012年

4 李亞范;廣泛性焦慮障礙患者聽(tīng)覺(jué)信息前注意加工的事件相關(guān)電位研究[D];大連醫(yī)科大學(xué);2014年

5 玄洪雷;廣泛性焦慮障礙患者情緒面孔無(wú)意識(shí)加工的事件相關(guān)電位研究[D];大連醫(yī)科大學(xué);2012年

6 李曉花;廣泛性焦慮障礙患者情緒語(yǔ)義無(wú)意識(shí)加工的事件相關(guān)電位研究[D];大連醫(yī)科大學(xué);2013年

7 張燕;基于體素分析方法的廣泛性焦慮障礙患者腦白質(zhì)彌散張量成像研究[D];中南大學(xué);2009年

8 王偉偉;歸脾湯治療廣泛性焦慮障礙的臨床研究[D];廣州中醫(yī)藥大學(xué);2010年

9 楊俊麗;廣泛性焦慮障礙表情信息前注意加工的事件相關(guān)電位研究[D];大連醫(yī)科大學(xué);2014年

10 徐云霞;社區(qū)廣泛性焦慮障礙患者的生活質(zhì)量及相關(guān)因素分析[D];復(fù)旦大學(xué);2013年

，

本文編號(hào)：1597233