本文關(guān)鍵詞： 多發(fā)性抽動癥 中西醫(yī)結(jié)合 多動寧膠囊 妥泰　出處：《福建中醫(yī)藥大學》2012年碩士論文　論文類型：學位論文

【摘要】：目的：觀察多動寧膠囊聯(lián)合妥泰治療小兒多發(fā)性抽動癥的臨床療效。 方法：采用非盲法隨機對照試驗設計方案,篩選符合入組標準的多發(fā)性抽動癥患兒60例。按隨機原則分為A組：單用中藥治療組(多動寧膠囊)20例；B組：單用西藥治療組(妥泰)20例;C組：試驗組(多動寧膠囊聯(lián)合妥泰)20例。觀察A、B、C三組治療前后的耶魯綜合抽動嚴重程度量表(YGTSS)評分及治療后相關(guān)副反應,從而比較三組治療的臨床療效。 結(jié)果：(1)試驗組(C組)臨床控制3例,顯效14例,好轉(zhuǎn)2例,無效1例,總有效率95%；單用西藥治療組(B組)臨床控制0例,顯效12例,好轉(zhuǎn)5例,無效3例,總有效率85%；單用中藥治療組(A組)臨床控制0例,顯效10例,好轉(zhuǎn)6例,無效4例,總有效率80%。試驗組療效明顯優(yōu)于單用西藥治療組及單用中藥治療組(P0.05)。(2)副反應情況：單用西藥治療組(B組)有3例出現(xiàn)厭食,1例出現(xiàn)頭暈,經(jīng)添加助消化及滋補腎陰的中成藥后癥狀緩解,單用中藥治療組(A組)及試驗組(C組)未見明顯副反應發(fā)生。 結(jié)論：通過試驗研究,試驗組(C組)治療小兒多發(fā)性抽動癥的臨床療效較為顯著,可更好地降低患兒YGTSS評分和治療后相關(guān)副反應,臨床總有效率95%,優(yōu)于單用西藥治療組(B組)和單用中藥治療組(A組)。多動寧膠囊聯(lián)合妥泰治療小兒多發(fā)性抽動癥可作為臨床治療的較好選擇。
[Abstract]:Objective: to observe the clinical effect of Duohuning capsule combined with topiramate in the treatment of children with multiple tic syndrome. Methods: a non-blind randomized controlled trial scheme was used to screen 60 children with multiple tic syndrome according to the criteria of admission. According to the random principle, 60 children were divided into two groups: group A, treated with traditional Chinese medicine alone (20 cases), and group A (20 cases) treated with traditional Chinese medicine alone. Group B: 20 cases were treated with western medicine alone; Group C: experimental group (20 cases) treated with Duoxunning capsule combined with topiramate. The YGTSS scores and related side effects were observed before and after treatment in group A BX C. The clinical effects of the three groups were compared. Results in the test group, 3 cases were clinically controlled, 14 cases were effective, 2 cases were improved, 1 case was ineffective, and the total effective rate was 95%. There were 0 cases of clinical control, 12 cases of remarkable effect, 5 cases of improvement and 3 cases of ineffectiveness. The total effective rate was 85%. There were 0 cases of clinical control, 10 cases of remarkable effect, 6 cases of improvement and 4 cases of ineffectiveness. The total effective rate was 80. The curative effect of the trial group was significantly better than that of the western medicine treatment group and the traditional Chinese medicine treatment group (P0.05. 2) side effects: there were 3 cases of anorexia in the western medicine alone treatment group (group B). One case had dizziness, the symptoms were relieved after adding the Chinese patent medicine of digestive aid and tonifying kidney yin, but no side effects were found in group A (treated with traditional Chinese medicine alone) and group C (test group). Conclusion: through the experimental study, the clinical effect of group C) in treating children with multiple tic syndrome is more significant, which can better reduce the YGTSS score of children and related side effects after treatment. The total clinical effective rate was 95%, which was better than that in group B (treated with western medicine alone) and group A (group A) treated with traditional Chinese medicine alone. The combination of Duohunning capsule and topiramate could be used as a better choice in the treatment of children with multiple tic syndrome.
【學位授予單位】：福建中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R749.94

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本文編號：1490563