本文關(guān)鍵詞： 孤獨(dú)癥譜系障礙 患病率 珠海市 兒童　出處：《中國(guó)兒童保健雜志》2014年06期 　論文類型：期刊論文

【摘要】：目的了解珠海市1.5~3歲孤獨(dú)癥譜系障礙(Autism Spectrum Disorders,ASD)的患病率及相關(guān)危險(xiǎn)因素。方法隨機(jī)抽取在珠海市生活的1.5~3歲兒童共5 500人,使用自編問卷和改良嬰幼兒孤獨(dú)癥篩查量表中文修訂版進(jìn)行初篩;對(duì)結(jié)果陽性者由�？漆t(yī)師根據(jù)臨床觀察及兒童孤獨(dú)癥評(píng)定量表評(píng)定結(jié)果進(jìn)行確診;最后統(tǒng)計(jì)分析ASD患兒的患病率及危險(xiǎn)因素。結(jié)果本次調(diào)查ASD患病率為29.45/104(95%CI為15.41/104~44.86/104),均為典型孤獨(dú)癥患兒,男女比例為6∶1。ASD組與非ASD組在性別、家庭收入、父母文化程度、母孕期間是否服用特殊藥物(避孕藥物、抗精神病藥物、抗癲癇病藥物等)、母孕期間是否補(bǔ)充葉酸、父親年齡的分布上存在明顯不同,差異有統(tǒng)計(jì)學(xué)意義(P0.05);回歸分析結(jié)果顯示家庭收入偏低、母孕期間服用特殊藥物、母孕期間未補(bǔ)充葉酸及出生時(shí)父親年齡偏高(35歲)或偏低(25歲)等可能為ASD的危險(xiǎn)因素。結(jié)論珠海市1.5~3歲ASD患病率低于國(guó)內(nèi)外的報(bào)道水平;母親懷孕時(shí)避免使用特殊藥物、積極補(bǔ)充葉酸,避免父親年齡過高或過低可能有助于降低ASD患病率。
[Abstract]:Objective to investigate Autism Spectrum Disorders of 3 years old autistic children in Zhuhai. Methods the prevalence and risk factors of ASD.Methods A total of 5 500 children aged from 1.5 to 3 years living in Zhuhai were randomly selected. Self-made questionnaire and modified Chinese version of infant autism screening scale were used for primary screening. The patients with positive results were diagnosed according to clinical observation and children autism rating scale. Results the prevalence of ASD in this survey was 29.45 / 104 / 95 and CI was 15.41 / 104 / 44.86 / 104 / 104). . The ratio of male to female was 6: 1. 1. The sex, family income, education level of parents, whether the mother took special drugs (contraception, antipsychotic) in ASD group and non-ASD group were 6: 1. 1. There were significant differences in the distribution of father's age and whether folic acid was added to the mother during pregnancy, and the difference was statistically significant (P 0.05). Regression analysis showed that the family income was low and the mother took special drugs during pregnancy. During pregnancy without folic acid supplementation and father's age at birth is higher than 35 years) or younger than 25 years). Conclusion the prevalence rate of ASD in Zhuhai is lower than that reported at home and abroad. Avoiding the use of special drugs during pregnancy, actively supplementing folic acid, and avoiding overage or overage of fathers may help reduce the prevalence of ASD.
【作者單位】： 珠海市婦幼保健院兒童心理行為科;珠海市婦幼保健院門診部;珠海市婦幼保健院產(chǎn)科三區(qū);
【基金】：珠海市科技計(jì)劃項(xiàng)目(201311140051)
【分類號(hào)】：R749.94
【正文快照】： 孤獨(dú)癥譜系障礙(autism spectrum disorders,ASD)是一類兒童廣泛性發(fā)育障礙性疾病,以社會(huì)互動(dòng)性交往障礙、語言溝通障礙以及局限和刻板的興趣和行為模式為基本特征,包括孤獨(dú)癥、阿斯伯格綜合征、雷特綜合征、兒童瓦解性精神障礙和未分類的廣泛性發(fā)育障礙等亞型,其中以孤獨(dú)癥和

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本文編號(hào)：1474323