本文關(guān)鍵詞：簡(jiǎn)化認(rèn)知行為治療對(duì)廣泛性焦慮患者生活質(zhì)量的影響　出處：《上海交通大學(xué)學(xué)報(bào)(醫(yī)學(xué)版)》2015年10期 　論文類(lèi)型：期刊論文

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【摘要】：目的比較簡(jiǎn)化認(rèn)知行為治療(SCBT)、藥物治療以及聯(lián)合治療3種干預(yù)方式對(duì)廣泛性焦慮(GAD)患者生活質(zhì)量的影響。方法針對(duì)符合DSM-5中GAD標(biāo)準(zhǔn),目前處于發(fā)作期的患者,運(yùn)用SCBT方法,采用多中心平行對(duì)照、盲法評(píng)估的方法,分為SCBT組、SCBT+藥物組和藥物組。主要結(jié)局指標(biāo)為生命質(zhì)量評(píng)分。結(jié)果完成8周干預(yù)103例患者,男51例,女52例,平均年齡是(37.8±11.6)歲;3組分別為32、38、33例,3組在年齡、性別和教育程度等方面的差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。基線時(shí)3組間僅在社會(huì)功能上差異有統(tǒng)計(jì)學(xué)意義(F=3.469,P=0.035),SCBT+藥物組明顯低于其他兩組;8周末,協(xié)方差分析結(jié)果表明,3組僅在軀體疼痛上差異有統(tǒng)計(jì)學(xué)意義(F=3.644,P=0.030),藥物組明顯高于其他兩組。組內(nèi)比較結(jié)果顯示:SCBT組除軀體健康問(wèn)題導(dǎo)致的角色受限、生命活力維度外,其他6個(gè)維度量表評(píng)分在治療前后的差異有統(tǒng)計(jì)學(xué)意義(P0.05);SCBT+藥物組在8個(gè)維度上治療前后的差異均有統(tǒng)計(jì)學(xué)意義(P0.05);藥物組除軀體功能,其他7個(gè)維度量表評(píng)分在治療前后的差異有統(tǒng)計(jì)學(xué)意義(P0.05)。3組間HAMA評(píng)分差異有統(tǒng)計(jì)學(xué)意義(P0.05);3組HAMD評(píng)分差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論單用SCBT、藥物治療及聯(lián)合治療3種干預(yù)方式均有助于改善GAD患者的生活質(zhì)量,三者間差異不顯著。
[Abstract]:Objective to compare the simplified cognitive behavior therapy (SCBT). Effects of drug therapy and combined therapy on the quality of life of patients with generalized anxiety disorder. The SCBT group was divided into two groups using SCBT method, multicenter parallel control method and blind method. Results after 8 weeks of intervention, there were 51 males and 52 females, with an average age of 37.8 鹵11.6 years. The age of the 3 groups were 32and 3833 cases respectively. There was no significant difference in sex and education level (P 0.05). At baseline, there were only significant differences in social function among the three groups (P < 0.05). The SCBT group was significantly lower than the other two groups. At the end of the 8th week, the results of covariance analysis showed that there was only significant difference in somatic pain among the three groups. The drug group was significantly higher than the other two groups. The results of intra-group comparison showed that the body health problems caused by the role limitation and vitality dimension in the SCBT group. The scores of the other six dimensions were significantly different before and after treatment (P 0.05). In SCBT group, there were significant differences in eight dimensions before and after treatment (P 0.05). In the drug group, there were significant differences in the scores of the other seven dimensional scales before and after treatment except for the somatic function. There were significant differences in the HAMA scores between the groups before and after treatment (P 0.05). There was no significant difference in HAMD scores among the three groups (P 0.05). Conclusion the three intervention methods of single SCBT, drug therapy and combined therapy are helpful to improve the quality of life of GAD patients. There was no significant difference among the three groups.
【作者單位】： 上海交通大學(xué)醫(yī)學(xué)院附屬精神衛(wèi)生中心;
【基金】：科技部“十二五”國(guó)家科技支撐項(xiàng)目(2012BAI01B04)~~
【分類(lèi)號(hào)】：R749.72
【正文快照】： 焦慮障礙在普通人群中發(fā)病率達(dá)到6%以上[1],排除標(biāo)準(zhǔn):1目前患嚴(yán)重軀體疾病、重度焦慮狀部分(15%~48%)常常遷延為慢性病程,嚴(yán)重影響患態(tài)或重度驚恐發(fā)作者。2有自傷行為或明顯自殺傾者的生活質(zhì)量[2,3]。廣泛性焦慮(generalized anxiety向者。3具有精神病性癥狀,排除強(qiáng)迫癥和創(chuàng)傷

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