本文關鍵詞：簡化認知行為治療對廣泛性焦慮患者生活質量的影響　出處：《上海交通大學學報(醫(yī)學版)》2015年10期 　論文類型：期刊論文

  更多相關文章： 簡化認知行為治療 廣泛性焦慮 生活質量 療效

【摘要】：目的比較簡化認知行為治療(SCBT)、藥物治療以及聯合治療3種干預方式對廣泛性焦慮(GAD)患者生活質量的影響。方法針對符合DSM-5中GAD標準,目前處于發(fā)作期的患者,運用SCBT方法,采用多中心平行對照、盲法評估的方法,分為SCBT組、SCBT+藥物組和藥物組。主要結局指標為生命質量評分。結果完成8周干預103例患者,男51例,女52例,平均年齡是(37.8±11.6)歲;3組分別為32、38、33例,3組在年齡、性別和教育程度等方面的差異無統(tǒng)計學意義(P0.05)�；�時3組間僅在社會功能上差異有統(tǒng)計學意義(F=3.469,P=0.035),SCBT+藥物組明顯低于其他兩組;8周末,協(xié)方差分析結果表明,3組僅在軀體疼痛上差異有統(tǒng)計學意義(F=3.644,P=0.030),藥物組明顯高于其他兩組。組內比較結果顯示:SCBT組除軀體健康問題導致的角色受限、生命活力維度外,其他6個維度量表評分在治療前后的差異有統(tǒng)計學意義(P0.05);SCBT+藥物組在8個維度上治療前后的差異均有統(tǒng)計學意義(P0.05);藥物組除軀體功能,其他7個維度量表評分在治療前后的差異有統(tǒng)計學意義(P0.05)。3組間HAMA評分差異有統(tǒng)計學意義(P0.05);3組HAMD評分差異無統(tǒng)計學意義(P0.05)。結論單用SCBT、藥物治療及聯合治療3種干預方式均有助于改善GAD患者的生活質量,三者間差異不顯著。
[Abstract]:Objective to compare the simplified cognitive behavior therapy (SCBT). Effects of drug therapy and combined therapy on the quality of life of patients with generalized anxiety disorder. The SCBT group was divided into two groups using SCBT method, multicenter parallel control method and blind method. Results after 8 weeks of intervention, there were 51 males and 52 females, with an average age of 37.8 鹵11.6 years. The age of the 3 groups were 32and 3833 cases respectively. There was no significant difference in sex and education level (P 0.05). At baseline, there were only significant differences in social function among the three groups (P < 0.05). The SCBT group was significantly lower than the other two groups. At the end of the 8th week, the results of covariance analysis showed that there was only significant difference in somatic pain among the three groups. The drug group was significantly higher than the other two groups. The results of intra-group comparison showed that the body health problems caused by the role limitation and vitality dimension in the SCBT group. The scores of the other six dimensions were significantly different before and after treatment (P 0.05). In SCBT group, there were significant differences in eight dimensions before and after treatment (P 0.05). In the drug group, there were significant differences in the scores of the other seven dimensional scales before and after treatment except for the somatic function. There were significant differences in the HAMA scores between the groups before and after treatment (P 0.05). There was no significant difference in HAMD scores among the three groups (P 0.05). Conclusion the three intervention methods of single SCBT, drug therapy and combined therapy are helpful to improve the quality of life of GAD patients. There was no significant difference among the three groups.
【作者單位】： 上海交通大學醫(yī)學院附屬精神衛(wèi)生中心;
【基金】：科技部“十二五”國家科技支撐項目(2012BAI01B04)~~
【分類號】：R749.72
【正文快照】： 焦慮障礙在普通人群中發(fā)病率達到6%以上[1],排除標準:1目前患嚴重軀體疾病、重度焦慮狀部分(15%~48%)常常遷延為慢性病程,嚴重影響患態(tài)或重度驚恐發(fā)作者。2有自傷行為或明顯自殺傾者的生活質量[2,3]。廣泛性焦慮(generalized anxiety向者。3具有精神病性癥狀,排除強迫癥和創(chuàng)傷

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