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注意力缺陷多動障礙相關因素及抑肝散治療效果的臨床研究

發(fā)布時間:2018-01-18 08:18

  本文關鍵詞:注意力缺陷多動障礙相關因素及抑肝散治療效果的臨床研究 出處:《中國臨床藥理學雜志》2015年15期  論文類型:期刊論文


  更多相關文章: 抑肝散 小兒多動癥 家庭環(huán)境 生活習慣 環(huán)境毒物


【摘要】:目的探討注意力缺陷多動障礙(ADHD)的臨床相關因素,評價抑肝散治療小兒多動癥的臨床效果。方法入選120例ADHD患兒作為研究對象,健康兒童120例作為對照組,通過問卷調查形式評價家庭環(huán)境、兒童生活習慣、兒童環(huán)境毒物接觸情況對ADHD的影響。另選取患兒中證屬脾虛肝亢者75例,其中試驗組38例,對照組37例,對照組給予單純行為治療,每周3次;試驗組在對照組治療基礎上,口服加味抑肝散150 m L,一日2次,療程為8周,分別于入組前,治療后4,8周行中醫(yī)證候積分評定和療效判斷。結果父母學歷低于初中、采取責罰教育方式、家庭月收入低于每月3000元、單親或隔代撫養(yǎng)家庭、人工喂養(yǎng)、父母為獨生子女均為發(fā)生ADHD的危險因素。作息不規(guī)律、缺乏愛好、睡眠紊亂、易食零食,接觸增塑劑(DEHP)次數越多及玩手機次數越頻繁更易患ADHD。試驗組控顯率為52.63%,總有效率為86.84%;對照組控顯率為24.32%,總有效率為43.24%,試驗組療效優(yōu)于對照組(P0.01)。治療8周后,2組中醫(yī)證候積分均顯著降低(P0.01),試驗組治療后中醫(yī)證候積分低于對照組,其改善程度更顯著。結論 ADHD發(fā)生與家庭環(huán)境、兒童生活習慣及接觸環(huán)境毒物有一定關系;抑肝散治療脾虛肝亢型ADHD療效確切。
[Abstract]:Objective to investigate the clinical related factors of attention deficit hyperactivity disorder (ADHD) and evaluate the clinical effect of Yigan San in treating ADHD in children with ADHD. Methods 120 children with ADHD were selected as the study objects. 120 healthy children were used as control group to evaluate family environment and children's living habits by questionnaire. In addition, 75 children with spleen deficiency and liver hyperactivity were selected, including 38 cases in the experimental group, 37 cases in the control group, and 3 times a week in the control group. Experimental group in the control group on the basis of treatment, oral Jiawei Yi Gan San 150ml, on 1st, twice, the course of treatment is 8 weeks, respectively before entering the group, 4 after treatment. Results the parents' educational background was lower than junior high school, the family monthly income was less than 3000 yuan per month, single parent or other generations raised family, artificial feeding. Parents are the only child of the risk factors for the occurrence of ADHD. Irregular work and rest, lack of hobbies, sleep disorder, easy to eat snacks. The more times of contact with plasticizer DEHPand the more frequency of playing mobile phones, the more susceptible to ADHD.The control rate of the test group was 52.63 and the total effective rate was 86.84. The control rate of the control group was 24.322.The total effective rate was 43.24.The curative effect of the experimental group was better than that of the control group (P 0.01). After 8 weeks of treatment, the effect of the test group was better than that of the control group. The scores of TCM syndromes in the two groups were significantly lower than those in the control group, and the scores of TCM syndromes in the experimental group were lower than those in the control group. Conclusion the occurrence of ADHD and the family environment are more significant. Children's living habits and exposure to environmental poisons are related to a certain extent; The curative effect of Yigan Powder on ADHD with spleen deficiency and liver hyperactivity was definite.
【作者單位】: 唐山市工人醫(yī)院中醫(yī)科;
【基金】:唐山市級發(fā)展與指導計劃基金資助項目(10130233a)
【分類號】:R749.94
【正文快照】: 常亞軍,劉秀敏,閆仲凱(唐山市工人醫(yī)院中醫(yī)科,河北唐山063021)CHANG Ya-jun,LIU Xiu-min,YAN Zhong-kai(Department Traditional Chinese Medi-cine,Tangshan Worker's HospitalAffiliated Rehabilitation Hospital,Tangshan 063021,Hebei Province,China)注意力缺陷多動障礙(

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