【摘要】：病理組織切片的預(yù)處理過程,包括組織樣本的選取、固定、脫水、透明、封蠟和包埋等多個(gè)流程,病理組織處理的質(zhì)量及處理速度,直接影響患者的診治,是醫(yī)學(xué)分析中非常重要的一個(gè)步驟。研究快速、自動(dòng)化病理組織處理系統(tǒng),是具有重要醫(yī)學(xué)價(jià)值的研究課題。病理組織處理系統(tǒng)涉及機(jī)械設(shè)計(jì)與工藝制造、生物病理學(xué)科、傳感器技術(shù)、嵌入式系統(tǒng)等多門學(xué)科,是一個(gè)涉及多門學(xué)科的綜合性課題。最終目的,是制作一臺(tái)處理速度快,全自動(dòng)的病理組織處理設(shè)備,有效提高病理組織處理的質(zhì)量,縮短病理處理時(shí)間。通過對(duì)病理組織處理過程的分析,構(gòu)建了一主多從的病理組織處理系統(tǒng)架構(gòu)。本文詳細(xì)介紹了病理組織處理系統(tǒng)從機(jī)部分的電路設(shè)計(jì)、程序?qū)崿F(xiàn),并介紹了病理組織處理系統(tǒng)中的一些關(guān)鍵技術(shù)。本文主要分為以下幾個(gè)部分:第一,緒論部分介紹了病理組織系統(tǒng)的課題來源及研究意義,總結(jié)了當(dāng)前國內(nèi)外病理組織處理系統(tǒng)的現(xiàn)狀,汲取現(xiàn)有設(shè)備的優(yōu)點(diǎn),并希望在設(shè)計(jì)的系統(tǒng)中對(duì)優(yōu)點(diǎn)進(jìn)行發(fā)揚(yáng),對(duì)現(xiàn)有設(shè)備的缺點(diǎn)進(jìn)行改進(jìn)。第二,介紹了病理組織處理的概念,以及病理組織處理的工作流程。分析了病理組織處理系統(tǒng)的主要機(jī)械結(jié)構(gòu),對(duì)電氣系統(tǒng)進(jìn)行了整體規(guī)劃。第三,使用超聲振蕩方法,加快病理處理過程。設(shè)計(jì)了超聲驅(qū)動(dòng)電路,并一步步解決設(shè)計(jì)驅(qū)動(dòng)電路過程中碰到的問題,最終拿出最優(yōu)的驅(qū)動(dòng)解決方案。給出了超聲驅(qū)動(dòng)的軟件實(shí)現(xiàn)思路。第四,為病理組織處理系統(tǒng)中的一些開關(guān)型負(fù)載設(shè)計(jì)了驅(qū)動(dòng)電路,并設(shè)計(jì)出特定功能模塊的工作流程。以給出硬件驅(qū)動(dòng)程序的方式,將各路開關(guān)型負(fù)載屏蔽起來,后續(xù)開發(fā)者只需按照接口要求,就可以直接控制相應(yīng)的開關(guān)型負(fù)載,不需要再進(jìn)行驅(qū)動(dòng)配置等繁瑣工作,并附出了驅(qū)動(dòng)程序的源碼。第五,對(duì)所做工作進(jìn)行一一驗(yàn)證,驗(yàn)證電路設(shè)計(jì)的正確性,驗(yàn)證系統(tǒng)移植、協(xié)議的正確性,對(duì)編寫的程序代碼的結(jié)果進(jìn)行驗(yàn)證。項(xiàng)目組成員參與整體病理組織處理系統(tǒng)的聯(lián)合調(diào)試,包括通訊的測(cè)試,及系統(tǒng)長時(shí)間運(yùn)行的穩(wěn)定性測(cè)試。第六,對(duì)所做項(xiàng)目作出總結(jié),并提出項(xiàng)目中需要改進(jìn)的地方。
[Abstract]:The preprocessing process of pathological tissue sections, including the selection of tissue samples, fixation, dehydration, transparency, wax sealing and embedding, and the quality and speed of pathological tissue treatment directly affect the diagnosis and treatment of patients. Is a very important step in medical analysis. The research of rapid and automatic pathological tissue management system is an important subject of medical value. Pathological tissue processing system involves many subjects, such as mechanical design and process manufacture, bio-pathology, sensor technology, embedded system and so on. It is a comprehensive subject involving many disciplines. The final goal is to make a fast and fully automatic pathological tissue processing equipment, which can effectively improve the quality of pathological tissue treatment and shorten the time of pathological treatment. Based on the analysis of pathological tissue processing process, a multi-subordinate pathological tissue processing system architecture is constructed. In this paper, the circuit design and program realization of the slave part of the pathological tissue processing system are introduced in detail, and some key technologies in the pathological tissue processing system are also introduced. This paper is mainly divided into the following parts: first, the introduction introduces the subject source and research significance of pathological tissue system, summarizes the current situation of pathological tissue processing system at home and abroad, and draws on the advantages of existing equipment. And hope to carry forward the advantages in the design system and improve the shortcomings of the existing equipment. Secondly, the concept of pathological tissue processing and the workflow of pathological tissue processing are introduced. The main mechanical structure of the pathological tissue management system is analyzed, and the overall planning of the electrical system is carried out. Third, ultrasound oscillation method is used to speed up the process of pathological treatment. The ultrasonic drive circuit is designed, and the problems encountered in the design of the drive circuit are solved step by step. Finally, the optimal driving solution is put forward. The software realization of ultrasonic drive is given. Fourthly, the drive circuit is designed for some switching load in the pathological tissue processing system, and the work flow of the specific function module is designed. In the way of hardware driver, the switching load can be shielded. The subsequent developer can control the switch load directly according to the interface requirement, and do not need to do the tedious work such as driver configuration, etc. And attached the driver source code. Fifthly, the paper verifies the correctness of the circuit design, the transplant of the system, the correctness of the protocol, and the result of the program code. Project team members participate in the joint debugging of the overall pathological tissue management system, including communication testing, and system stability testing for long-term operation. Sixth, to make a summary of the project, and put forward the project needs to be improved.
【學(xué)位授予單位】：山東師范大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R361
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本文編號(hào)：2244870