【摘要】：目的探討早期乳酸清除率對(duì)呼吸衰竭患者預(yù)后評(píng)估的作用。方法收集呼吸內(nèi)科重癥監(jiān)護(hù)室(RICU)內(nèi)入院時(shí)血乳酸升高的呼吸衰竭患者117例,檢測(cè)治療前、治療后12 h、24 h、48 h及72 h動(dòng)脈血乳酸值及動(dòng)脈血?dú)?計(jì)算12 h乳酸清除率,并作入院時(shí)及入院后12 h急性生理學(xué)及慢性健康狀況評(píng)價(jià)Ⅱ(APACHEⅡ)評(píng)分。比較血乳酸恢復(fù)正常時(shí)間與患者預(yù)后的關(guān)系;比較不同預(yù)后患者的臨床特征;以血乳酸清除率10%為界分為高乳酸清除率組(10%)和低乳酸清除率組(10%),比較兩組患者的預(yù)后及相關(guān)指標(biāo)的差異。結(jié)果血乳酸值24 h內(nèi)恢復(fù)正常組與血乳酸值72 h內(nèi)未恢復(fù)正常組比較,預(yù)后有明顯差異(P0.001);存活組12 h乳酸清除率(43.6%±26.8%)明顯高于死亡組(12.3%±39.1%,P0.01);高乳酸清除率組病死率(25.8%)明顯低于低乳酸清除率組(71.4%,P0.01)。結(jié)論早期乳酸清除率可作為判斷呼吸衰竭患者預(yù)后的一個(gè)指標(biāo)。
[Abstract]:Objective to investigate the effect of early lactate clearance rate on prognosis of patients with respiratory failure. Methods 117 patients with respiratory failure with elevated blood lactic acid on admission in (RICU) of respiratory internal medicine department were collected. The arterial blood lactic acid and arterial blood gas were measured before and after treatment for 24 h and 72 h, and the clearance rate of lactic acid at 12 h was calculated. The acute physiology and chronic health status evaluation 鈪，

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