發(fā)布時間：2018-10-09 08:26

【摘要】：目的探討脈沖振蕩肺功能(IOS)評價塵肺患者肺功能的臨床價值。方法對119例塵肺患者和79例健康者依次進(jìn)行IOS及PFT檢測,分析兩組人群兩種肺功能各項(xiàng)指標(biāo)之間的差異、相關(guān)性。結(jié)果對于早期(壹期)塵肺組,PFT中FEV1、FVC、FEV1/FVC、MVV較健康對照組無明顯差異,MEF25、MEF50、MEF75則明顯降低,差異有統(tǒng)計學(xué)意義(P0.05);而IOS參數(shù)中Z5、X5、AX明顯升高,差異有統(tǒng)計學(xué)意義(P0.05)。在PFT正常的塵肺患者中,壹期塵肺組的IOS參數(shù)較健康對照組無明顯差異,而貳叁期塵肺組的Z5、X5、Fres則明顯升高,差異有統(tǒng)計學(xué)意義(P0.05);壹期塵肺組和貳叁期塵肺組IOS異常率均較PFT高,差異有統(tǒng)計學(xué)意義(P0.05);IOS參數(shù)Z5、R5、R20、R5-R20、Fres、AX與PFT指標(biāo)FVC、FEVl、FEVl/FVC、MVV、MEF25、MEF50、MEF75呈負(fù)相關(guān),X5則呈正相關(guān),兩種肺功能指標(biāo)相關(guān)系數(shù)(絕對值)按由高到低依次為:Fres與FEV1/FVC(r=-0.566)、Fres與FEVl(r=-0.557)、Z5與FEVl/FVC(r=-0.544)、AX與FEVl/FVC(r=-0.541)、R5與FEVl/FVC(r=-0.541),在貳叁期塵肺組中相關(guān)性更高。結(jié)論 IOS可以發(fā)現(xiàn)早期塵肺患者的氣道阻力異常,其操作簡便、對受檢者配合度要求低,可能是塵肺患者肺功能評價的有益補(bǔ)充。
[Abstract]:Objective to evaluate the clinical value of pulsed oscillatory pulmonary function (IOS) in evaluating pulmonary function in patients with pneumoconiosis. Methods IOS and PFT were detected in 119 patients with pneumoconiosis and 79 healthy subjects respectively. The difference and correlation between the two indexes of pulmonary function were analyzed. Results there was no significant difference in FEV1,FVC,FEV1/FVC,MVV between the early stage and the control group (P 0.05), but there was a significant difference between the two groups (P0.05), while the IOS parameter of Z5F5AX was significantly higher than that of the control group (P0.05). In PFT normal pneumoconiosis patients, the IOS parameters of stage 1 pneumoconiosis group were not significantly different from those of healthy control group, but Z5 X 5 Fres level of stage 223 pneumoconiosis group was significantly higher than that of control group (P0.05), the abnormal rate of IOS in stage 1 pneumoconiosis group and stage 23 pneumoconiosis group was higher than that in PFT group. 宸紓鏈夌粺璁″鎰忎箟(P0.05);IOS鍙傛暟Z5,R5,R20,R5-R20,Fres,AX涓嶱FT鎸囨爣FVC,FEVl,FEVl/FVC,MVV,MEF25,MEF50,MEF75鍛堣礋鐩稿叧,X5鍒欏憟姝ｇ浉鍏，

本文編號：2258658