【摘要】：目的探討慢性阻塞性肺疾病患者肺部感染患者血清炎性因子的變化情況,為其診治提供依據。方法選取2012年1月-2013年1月醫(yī)院的34例慢性阻塞性肺疾病發(fā)生肺部感染患者為A組,另將同一時期的34例慢性阻塞性肺疾病患者選為B組,同一時期的于醫(yī)院進行體檢的34名健康人員選為C組,將3組人員的血清促炎因子與抑炎因子水平進行檢測比較。結果 A組的血清IL-2水平為(4.24±0.56)μg/L,低于B組的(6.57±0.79)μg/L與C組的(8.89±1.13)μg/L,血清IL-6、TNF-α與IFN-γ水平分別為(16.33±1.78)pg/ml、(2.31±0.24)ng/ml和(20.32±2.14)μg/ml,其均高于B組的(11.74±1.29)pg/ml、(1.57±0.15)ng/ml和(14.68±1.62)μg/ml與C組的(6.86±0.92)pg/ml、(0.92±0.10)ng/ml和(8.78±0.99)μg/ml,而A組患者中重度肺部感染患者血清IL-2水平低于輕度感染患者,IL-6、TNF-α與IFN-γ水平則高于輕度感染患者,差異均有統(tǒng)計學意義(P0.05)。結論慢性阻塞性肺疾病患者肺部感染患者血清炎性因子波動相對較大,對于感染的存在及嚴重程度均有一定的指示作用。
[Abstract]:Objective to investigate the changes of serum inflammatory factors in patients with chronic obstructive pulmonary disease (COPD). Methods from January 2012 to January 2013, 34 patients with chronic obstructive pulmonary disease (COPD) were selected as group A and 34 patients with chronic obstructive pulmonary disease (COPD) in the same period were selected as group B. 34 healthy persons in the same period were selected as group C, and the serum levels of proinflammatory factor and anti-inflammatory factor were measured and compared among the three groups. 緇撴灉 A緇勭殑琛，

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