【摘要】：目的探討降鈣素原(PCT)和C-反應(yīng)蛋白(CRP)在老年患者感染性肺炎中的變化,以及CRP聯(lián)合PCT在臨床診斷中的價值。方法選取2012年9月-2016年9月180例醫(yī)院收治的老年患者臨床資料,按照有無肺炎分為兩組,其中肺炎組90例,無肺炎組90例,檢測兩組患者PCT和CRP,比較兩組入院后第1、7、10天血清PCT、CRP的動態(tài)變化,將肺炎組根據(jù)治療方法隨機(jī)分為常規(guī)治療組和PCT聯(lián)合CRP指導(dǎo)治療組,觀察PCT聯(lián)合CRP指導(dǎo)治療效果。結(jié)果兩組患者CRP水平隨著住院時程下降,住院第1、7天時,兩組CRP及PCT水平差異有統(tǒng)計學(xué)意義(P0.05),住院第10天時,兩組CRP及PCT水平差異無統(tǒng)計學(xué)意義;肺炎組中常規(guī)治療和PCT聯(lián)合CRP指導(dǎo)治療患者抗菌藥物療程、住院費(fèi)用比較,差異有統(tǒng)計學(xué)意義(P0.05),抗菌藥物使用時間及住院費(fèi)用少于常規(guī)治療患者,住院時間無明顯差異,不同治療方法的治療效果無明顯差異。結(jié)論 CRP聯(lián)合PCT能早期診斷老年感染性肺炎,且動態(tài)反映肺炎進(jìn)展情況,可以指導(dǎo)臨床治療。
[Abstract]:Objective to investigate the changes of procalcitonin (PCT) and C-reactive protein (CRP) in the elderly patients with infectious pneumonia and the value of CRP combined with PCT in clinical diagnosis. Methods 180 elderly patients admitted from September 2012 to September 2016 were divided into two groups according to whether they had pneumonia, including 90 cases in pneumonia group, 90 cases in non-pneumonia group, 90 cases in pneumonia group and 90 cases in non-pneumonia group. PCT and CRP were detected in two groups, and the dynamic changes of serum PCTV-CRP were compared between the two groups on the 1st day after admission. The pneumonia group was randomly divided into routine treatment group and PCT combined with CRP guidance treatment group according to the treatment method. The therapeutic effect of PCT combined with CRP guidance was observed. Results the CRP level of the two groups decreased with the duration of hospitalization. The CRP and PCT levels of the two groups were significantly different at the 1st day of hospitalization (P0.05), but on the 10th day of hospitalization, there was no significant difference in CRP and PCT levels between the two groups. In the pneumonia group, there were significant differences in the course of antibiotics treatment and the hospitalization cost between the patients treated with routine therapy and PCT combined with CRP (P0.05). The duration of use of antibiotics and the cost of hospitalization were less than those of the patients treated with routine therapy, and there was no significant difference in hospitalization time. There was no significant difference in the effect of different treatment methods. Conclusion CRP combined with PCT can early diagnose senile infectious pneumonia and dynamically reflect the progress of pneumonia, and can guide clinical treatment.
【作者單位】： 攀枝花市第二人民醫(yī)院呼吸科;
【分類號】：R563.1

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本文編號：2171210