【摘要】：目的:探討丹參、燈盞花素注射液對(duì)慢性阻塞性肺疾病急性加重期患者D-二聚體的影響。方法:選擇院內(nèi)收治的72例慢性阻塞性肺疾病急性加重期的患者,隨機(jī)將其分為觀察組和對(duì)照組各36例,均給予院內(nèi)常規(guī)醫(yī)護(hù)措施干預(yù),觀察組在此基礎(chǔ)上加用丹參注射液進(jìn)行治療,對(duì)照組在基礎(chǔ)醫(yī)護(hù)措施上加用燈盞花素注射液進(jìn)行治療,對(duì)比兩組臨床治療效果及對(duì)患者機(jī)體D-二聚體含量的影響。結(jié)果:觀察組臨床治療有效率與對(duì)照組比較差異無統(tǒng)計(jì)學(xué)意義(P0.05),治療后觀察組D-二聚體水平顯著低于對(duì)照組及治療前,比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療后兩組PaO_2水平顯著升高,較治療前比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療后兩組PaCO_2水平顯著降低,較治療前比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:對(duì)于處于慢性阻塞性肺疾病急性加重期的患者而言,臨床中相較燈盞花素注射液選擇應(yīng)用丹參注射液進(jìn)行治療,不僅在一定程度上可顯著改善患者血栓前狀態(tài),而且還能較為有效的降低患者機(jī)體D-二聚體水平,有利于患者的康復(fù),值得臨床推廣應(yīng)用。
[Abstract]:Objective: to investigate the effect of Danshen injection and breviscapine injection on D-dimer in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods: 72 patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) were randomly divided into observation group (n = 36) and control group (n = 36). The observation group was treated with Salvia miltiorrhiza injection and the control group was treated with breviscapine injection on the basis of basic medical measures. Results: there was no significant difference in the effective rate of clinical treatment between the observation group and the control group (P0.05). After treatment, the level of D-dimer in the observation group was significantly lower than that in the control group and before treatment, the difference was statistically significant (P0.05). Compared with before treatment, the difference was statistically significant (P0.05); after treatment, the level of Paco _ 2 in the two groups was significantly lower than that before treatment (P0.05). Conclusion: compared with breviscapine injection, salvia miltiorrhiza injection can significantly improve the prethrombotic state in patients with chronic obstructive pulmonary disease (COPD). Moreover, it can effectively reduce the level of D-dimer in patients, which is beneficial to the rehabilitation of patients and is worthy of clinical application.
【作者單位】： 浙江大學(xué)附屬第一醫(yī)院浦江分院呼吸內(nèi)科;
【分類號(hào)】：R563.9
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本文編號(hào)：2134209