本文選題：良性氣道瘢痕性狹窄 + 治療現(xiàn)狀��； 參考：《重慶醫(yī)科大學(xué)》2017年碩士論文

【摘要】：良性氣道瘢痕狹窄(Benign cicatricial airway stenosis)是多種原因所引起的氣道瘢痕增生性、攣縮性或塌陷性狹窄,是臨床上常見(jiàn)疾病,嚴(yán)重氣道狹窄可導(dǎo)致呼吸衰竭而影響患者的生命活動(dòng)。本病病因包括氣管支氣管結(jié)核、氣管插管和氣管切開(kāi)、支氣管吻合、胸部創(chuàng)傷、支架置入或吸入性損傷等多種因素。國(guó)外首要致病因素是氣管插管和氣管切開(kāi),而國(guó)內(nèi)最常見(jiàn)的致病因素是氣管支氣管結(jié)核。良性氣道瘢痕狹窄按病理類(lèi)型可分網(wǎng)狀狹窄、肉芽腫性狹窄、復(fù)雜性狹窄,根據(jù)不同的狹窄類(lèi)型可以選擇內(nèi)科氣道介入、外科手術(shù)及藥物治療等不同治療手段,雖然治療方式多樣,但均有其不足之處。當(dāng)前尚無(wú)指導(dǎo)治療的統(tǒng)一標(biāo)準(zhǔn),臨床上治療策略不一,略顯混亂,總體治療效果差,狹窄容易復(fù)發(fā)。不斷提高療效、盡量減少甚或消除各種并發(fā)癥一直是臨床工作中關(guān)注的焦點(diǎn)。近年來(lái)新興治療手段迅速更新,但治療良性氣道瘢痕狹窄依然面臨挑戰(zhàn)。本文意在對(duì)良性氣道瘢痕的形成機(jī)制、治療現(xiàn)狀及研究新進(jìn)展作綜述,希望能為臨床工作者在制定診療方案時(shí)提供良好參考。
[Abstract]:Benign airway scar stenosis (cicatricial airway stenosis) is a common clinical disease caused by hyperplastic contracture or collapse of airway scar. Severe airway stenosis can lead to respiratory failure and affect the life activities of patients. The causes include tracheobronchial tuberculosis, tracheal intubation and tracheotomy, bronchial anastomosis, thoracic trauma, stent implantation or inhalation injury. Tracheal intubation and tracheotomy are the main pathogenic factors in foreign countries, and the most common pathogenic factors in China are tracheobronchial tuberculosis. Benign airway scar stenosis can be divided into reticular stenosis, granulomatous stenosis and complex stenosis according to pathological type. According to different types of stenosis, different treatment methods such as internal airway intervention, surgical operation and drug therapy can be selected. Although the treatment methods are diverse, but all have their shortcomings. At present, there is no unified standard to guide the treatment, the clinical treatment strategy is different, slightly chaotic, the overall treatment effect is poor, the stenosis is easy to recur. It is always the focus of clinical work to improve the curative effect and reduce or eliminate all kinds of complications as far as possible. In recent years, the treatment of benign airway scar stenosis is still facing challenges. The purpose of this article is to summarize the mechanism of benign airway scar formation, treatment status and new research progress, hoping to provide a good reference for clinicians in making diagnosis and treatment plan.
【學(xué)位授予單位】：重慶醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類(lèi)號(hào)】：R562.12

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本文編號(hào)：2021904