本文選題：慢性嗜酸性粒細(xì)胞性肺炎 + 診斷　； 參考：《中國(guó)呼吸與危重監(jiān)護(hù)雜志》2017年03期

【摘要】：目的總結(jié)慢性嗜酸性粒細(xì)胞性肺炎的臨床特點(diǎn)、診斷及治療方法,提高診治水平。方法回顧性分析2011年1月至2015年1月5例慢性嗜酸性粒細(xì)胞性肺炎患者的臨床資料。結(jié)果患者中男2例,女3例。合并過敏性鼻炎1例,合并支氣管哮喘2例,具有過敏史者2例,合并變應(yīng)性皮疹1例。主要臨床表現(xiàn)為發(fā)熱、咳嗽、咯痰、呼吸困難和胸痛,常伴乏力、納差和體重下降。主要體征為兩肺濕Up音、散在哮鳴音,亦可聞及爆裂音。5例均有外周血嗜酸性粒細(xì)胞計(jì)數(shù)升高,嗜酸性粒細(xì)胞百分比升高,支氣管肺泡灌洗液中嗜酸性粒細(xì)胞百分比明顯升高。主要影像表現(xiàn)為兩肺浸潤(rùn)影,斑片實(shí)變影和磨玻璃影。5例均接受糖皮質(zhì)激素治療。隨訪中病情復(fù)發(fā)1例。結(jié)論慢性嗜酸性粒細(xì)胞性肺炎起病隱匿,臨床表現(xiàn)缺乏特異性,常合并哮喘及變應(yīng)性皮炎,多數(shù)患者外周血和肺泡灌洗液嗜酸性粒細(xì)胞數(shù)明顯升高,典型影像表現(xiàn)為周邊和胸膜下分布為主的肺浸潤(rùn)影。
[Abstract]:Objective to summarize the clinical features, diagnosis and treatment of chronic eosinophil pneumonia. Methods the clinical data of 5 patients with chronic eosinophil pneumonia from January 2011 to January 2015 were retrospectively analyzed. Results there were 2 males and 3 females. There were 1 case with allergic rhinitis, 2 cases with bronchial asthma, 2 cases with allergic history and 1 case with allergic rash. The main clinical manifestations are fever, cough, sputum, dyspnea and chest pain, often accompanied by fatigue, anorexia and weight loss. The main signs were wet up in both lungs, wheezing scattered, and buzzer. The eosinophil count, eosinophil percentage and eosinophil percentage in bronchoalveolar lavage fluid were all increased in 5 cases of eosinophil count in peripheral blood, and the percentage of eosinophil in bronchoalveolar lavage fluid was obviously increased. The main imaging findings were pulmonary infiltration, macular consolidation and glass-grinding. 5 cases were treated with glucocorticoid. Recurrence occurred in 1 case during follow-up. Conclusion chronic eosinophil pneumonia is characterized by occult onset and lack of specificity in clinical manifestations. It is often associated with asthma and allergic dermatitis. The number of eosinophils in peripheral blood and alveolar lavage fluid is significantly increased in most patients. Typical imaging features were pulmonary infiltrating shadows mainly distributed in peripheral and subpleural areas.
【作者單位】： 上海交通大學(xué)醫(yī)學(xué)院附屬新華醫(yī)院呼吸科;上海交通大學(xué)醫(yī)學(xué)院附屬新華醫(yī)院病理科;
【分類號(hào)】：R563.1

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本文編號(hào)：1960242