早期目標(biāo)導(dǎo)向型鎮(zhèn)靜改善老年肺炎機(jī)械通氣患者腸內(nèi)營養(yǎng)耐受性的效果
本文選題:早期目標(biāo)導(dǎo)向型鎮(zhèn)靜 + 機(jī)械通氣肺炎。 參考:《中國老年學(xué)雜志》2017年08期
【摘要】:目的探究早期目標(biāo)導(dǎo)向型鎮(zhèn)靜(EGDS)在改善機(jī)械通氣老年肺炎患者腸內(nèi)營養(yǎng)耐受性的臨床效果。方法 68例重癥監(jiān)護(hù)室(ICU)接受機(jī)械通氣治療的肺炎患者按入院先后分為EGDS組(38例)和對(duì)照組(30例)。對(duì)照組實(shí)行標(biāo)準(zhǔn)化鎮(zhèn)靜策略,EGDS組實(shí)行EGDS策略進(jìn)行鎮(zhèn)靜。停藥后就兩組呼吸及循環(huán)參數(shù)進(jìn)行比較,同時(shí)對(duì)比兩組腸內(nèi)營養(yǎng)開始時(shí)間、營養(yǎng)目標(biāo)達(dá)標(biāo)時(shí)間及其機(jī)械通氣時(shí)間,并就各項(xiàng)并發(fā)癥發(fā)生情況進(jìn)行比較。結(jié)果用藥期間,兩組平均動(dòng)脈壓(MBP)、呼吸頻率(RR)、動(dòng)脈氧分壓(PaO_2)無顯著差異(P0.05),兩組心率(HR)存在顯著差異(P0.05)。EGDS組機(jī)械通氣時(shí)間、腸內(nèi)營養(yǎng)開始時(shí)間和營養(yǎng)目標(biāo)達(dá)標(biāo)時(shí)間均顯著低于對(duì)照組(P0.05)。腸內(nèi)營養(yǎng)并發(fā)癥方面,EGDS組胃潴留、嘔吐、反流誤吸發(fā)生率均顯著低于對(duì)照組(P0.05)。結(jié)論 EGDS的應(yīng)用避免了對(duì)機(jī)械通氣肺炎患者的過度鎮(zhèn)靜,對(duì)腸胃功能起到一定的保護(hù)作用,使其腸內(nèi)營養(yǎng)耐受性得到顯著提升。
[Abstract]:Objective to investigate the clinical effect of early goal-oriented sedation (EGDS) in improving enteral nutrition tolerance in elderly patients with mechanical ventilation pneumonia. Methods 68 patients with pneumonia treated by mechanical ventilation in intensive care unit were divided into EGDS group (n = 38) and control group (n = 30). The control group was treated with standardized sedative strategy and the EGDS group was treated with EGDS strategy. The respiratory and circulatory parameters of the two groups were compared after withdrawal, and the beginning time of enteral nutrition, the time of meeting the nutritional target and the time of mechanical ventilation were compared, and the occurrence of various complications was compared. Results there was no significant difference in mean arterial pressure (MBP), respiratory frequency (RRN) and arterial partial pressure of oxygen (PaO2) between the two groups during the treatment period (P 0.05), but there was a significant difference in HR between the two groups (P 0.05) and the time of mechanical ventilation in EGDS group. The beginning time of enteral nutrition and the time of reaching the standard of nutrition target were significantly lower than that of the control group (P 0.05). The incidence of gastric retention, vomiting and reflux aspiration in EGDS group was significantly lower than that in control group (P 0.05). Conclusion the application of EGDS can avoid excessive sedation in patients with mechanical ventilation pneumonia, protect gastrointestinal function and improve enteral nutrition tolerance.
【作者單位】: 紹興市人民醫(yī)院重癥醫(yī)學(xué)科;
【基金】:浙江省醫(yī)藥衛(wèi)生科技計(jì)劃(No.2016KYB308)
【分類號(hào)】:R563.1
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