本文選題：鹽酸氨溴索 + 昏迷患者��； 參考：《中華醫(yī)院感染學雜志》2014年14期

【摘要】：目的探討鹽酸氨溴索治療昏迷患者肺部感染的臨床效果,以期提高臨床治療水平,降低感染率。方法選取2011年8月-2013年5月118例昏迷發(fā)生肺部感染患者為研究對象,將其隨機分為兩組,對照組60例采用基礎(chǔ)治療,觀察組58例予以基礎(chǔ)治療加鹽酸氨溴索霧化吸入和靜脈滴注治療,比較兩組治療后臨床效果;采用SPSS16.0軟件進行統(tǒng)計分析。結(jié)果對照組治愈率為21.67%、顯效率為35.00%、有效率為16.67%、總有效率為73.33%;觀察組治愈率為65.52%、顯效率為20.69%、有效率為8.62%、總有效率為94.83%,兩組比較差異有統(tǒng)計學意義(P0.05);兩組患者住院時間、咳嗽緩解時間、體溫恢復(fù)正常時間、昏迷好轉(zhuǎn)時間、胸片陰影吸收時間、體征恢復(fù)時間、血常規(guī)正常時間比較差異有統(tǒng)計學意義(P0.05);兩組治療后第7、10、14天在無創(chuàng)血氧飽和度(SaO2)和血氧分壓(PO2)比較差異有統(tǒng)計學意義(P0.05)。結(jié)論鹽酸氨溴索治療昏迷并肺部感染臨床效果顯著,安全性高。
[Abstract]:Objective to investigate the clinical effect of ambroxol hydrochloride in the treatment of pulmonary infection in coma patients in order to improve the clinical treatment level and reduce the infection rate. Methods from August 2011 to May 2013, 118 patients with pulmonary infection in coma were randomly divided into two groups. 60 patients in control group were treated with basic therapy. 58 cases in the observation group were treated with basic therapy, atomization inhalation of ambroxol hydrochloride and intravenous drip, and the clinical effects were compared between the two groups, and the statistical analysis was carried out by SPSS16.0 software. Results in the control group, the cure rate was 21.67, the markedly effective rate was 35.00, the effective rate was 16.67 and the total effective rate was 73.33; in the observation group, the cure rate was 65.52, the markedly effective rate was 20.6920. The effective rate was 8.62 and the total effective rate was 94.83. The difference between the two groups was statistically significant (P0.05). Cough relief time, body temperature recovery time, coma improvement time, chest film shadow absorption time, physical sign recovery time, There was significant difference in the normal time of blood routine between the two groups (P 0.05), and there was a significant difference between the two groups in the non-invasive oxygen saturation (SaO2) and the blood oxygen partial pressure (PO2) on the 14th day after treatment (P 0.05). Conclusion Ambroxol hydrochloride is effective and safe in the treatment of coma and pulmonary infection.
【作者單位】： 南陽市中心醫(yī)院神經(jīng)內(nèi)科;
【基金】：河南省衛(wèi)生廳專項支持計劃基金資助項目(HW-2010B-048)
【分類號】：R563.1

【參考文獻】

相關(guān)期刊論文 前7條

1 佘志峰;沈金屏;;氨溴索聯(lián)合地塞米松對重型顱腦外傷后肺部感染霧化吸入的療效觀察[J];海峽藥學;2012年06期

2 鄭珍香;葉光福;吳志雄;楊亞東;林仰東;楊博;羅正超;;支氣管肺泡灌洗聯(lián)合大劑量鹽酸氨溴索在難治性肺部感染中的應(yīng)用[J];嶺南急診醫(yī)學雜志;2008年06期

3 張琳;;鹽酸氨溴索濕化吸痰法預(yù)防重型腦出血患者并發(fā)肺部感染的研究[J];臨床和實驗醫(yī)學雜志;2011年06期

4 焦其英;任運清;楊t熋，

本文編號：1863527