本文選題：氨溴索靜注 + 霧化吸入�。� 參考：《中華醫(yī)院感染學雜志》2017年19期

【摘要】：目的探討鹽酸氨溴索靜注聯(lián)合霧化吸入在治療腦梗死合并肺部感染患者中的臨床療效。方法選取醫(yī)院2015年12月-2016年12月收治的腦梗死合并肺部感染患者98例,隨機分為觀察組和對照組,各49例,均行腦梗死及肺部感染常規(guī)治療,對照組患者給予鹽酸氨溴索注射液靜脈注射,觀察組在對照組基礎上聯(lián)合復方異丙托溴銨溶液+布地奈德霧化吸入治療,記錄并分析兩組患者呼吸道癥狀消失時間、平均住院時間及治療前后血氣指標與肺功能檢測指標。結果觀察組患者治療總有效率達到95.92%顯著高于對照組79.59%(P0.05);觀察組各臨床表現(xiàn)完全消失時間及平均住院時間均顯著短于對照組(P0.01);兩組患者治療前各項血氣指標pH值、氧分壓(PaO_2),二氧化碳分壓(PaCO_2)及肺功能指標(FEV1%)比較差異無統(tǒng)計學意義;治療后上述各項指標均較治療前有明顯改善(P0.05),但觀察組改善情況更顯著于對照組(P0.05)。結論鹽酸氨溴索靜注聯(lián)合霧化吸入在治療腦梗死合并肺部感染的患者中療效較顯著,顯然比單純運用鹽酸氨溴索靜注治療有優(yōu)勢,且在一定程度上迅速緩解患者臨床癥狀,縮短住院時間,緩解患者經濟和精神壓力。
[Abstract]:Objective to investigate the clinical efficacy of ambroxol hydrochloride combined with atomization inhalation in the treatment of cerebral infarction with pulmonary infection. Methods from December 2015 to December 2016, 98 patients with cerebral infarction complicated with pulmonary infection were randomly divided into observation group and control group, 49 patients in each group were treated with routine treatment of cerebral infarction and pulmonary infection. The patients in the control group were given ambroxol hydrochloride injection intravenously, the observation group was treated with budesonide atomization inhalation of compound ipratropium bromide solution on the basis of the control group, and the time for the disappearance of respiratory symptoms in the two groups was recorded and analyzed. Mean hospitalization time, blood gas and pulmonary function before and after treatment. Results the total effective rate of treatment in the observation group was 95.92%, significantly higher than that in the control group (79.59%), and the total disappearance time and average hospitalization time of each clinical manifestation in the observation group were significantly shorter than that in the control group (P 0.01), and the pH values of the blood gas indexes before treatment were significantly shorter in the observation group than in the control group. There was no significant difference in Pao _ 2, Paco _ 2 and FEV _ 1 (P _ (0.05), but the improvement in observation group was more significant than that in control group (P _ (0.05) P _ (0.05), but there was no significant difference in Pao _ (2), Paco _ (2) and FEV _ 1 (P _ (0.05), but the improvement in observation group was more significant than that in control group (P < 0.05). Conclusion Ambroxol hydrochloride combined with atomization inhalation is more effective than ambroxol hydrochloride in the treatment of cerebral infarction patients with pulmonary infection. Shorten the length of stay in hospital, ease the patient's economic and mental stress.
【作者單位】： 金華市人民醫(yī)院神經內科;金華市第二醫(yī)院老年科;
【基金】：浙江省醫(yī)藥衛(wèi)生科技計劃基金資助項目(2013KYD276)
【分類號】：R563.1;R743.3

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