發(fā)布時(shí)間：2018-04-29 22:09

  本文選題：哮喘 + 慢性阻塞性肺疾病　； 參考：《中國藥學(xué)雜志》2017年16期

【摘要】：目的探討藥師為哮喘和慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者提供分級藥學(xué)服務(wù)的模式。方法以我院哮喘和COPD患者為研究對象,結(jié)合哮喘和COPD臨床指南,制定分級藥學(xué)服務(wù)標(biāo)準(zhǔn)。收集患者256例,隨機(jī)分成干預(yù)組和對照組,根據(jù)分級標(biāo)準(zhǔn)對患者實(shí)施不同級別的藥學(xué)服務(wù)。將兩組患者干預(yù)前、干預(yù)3個(gè)月后、干預(yù)6個(gè)月后的分級評分、用藥依從性和肺功能指標(biāo)(FEV1/FVC、FEV1%預(yù)計(jì)值)進(jìn)行兩組間的比較,觀察不良反應(yīng)發(fā)生情況,急性加重發(fā)作次數(shù)大于等于已發(fā)生情況以及臨床有效控制率。結(jié)果與對照組相比,干預(yù)6個(gè)月后,干預(yù)組一級服務(wù)比例下降了25%;不良反應(yīng)發(fā)生率減少了7.82%;急性加重次數(shù)大于等于發(fā)生率降低了7.81%;臨床有效控制率提高了23.43%;FEV1/FVC、FEV1%預(yù)計(jì)值和用藥依從性得到顯著改善,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論通過對哮喘和COPD慢性病患者實(shí)施分級藥學(xué)服務(wù),可以幫助藥師在最短的時(shí)間內(nèi)找到需要重點(diǎn)服務(wù)的對象,同時(shí)達(dá)到提高藥學(xué)服務(wù)質(zhì)量和臨床療效的目的。
[Abstract]:Objective to explore the model of pharmacists providing graded pharmacological care for patients with asthma and chronic obstructive pulmonary disease (CPD). Methods the patients with asthma and COPD in our hospital were studied, and the standard of graded pharmacological care was established in combination with the clinical guidelines of asthma and COPD. 256 patients were randomly divided into intervention group and control group. Before intervention, 3 months after intervention, 6 months after intervention, grading score, compliance and pulmonary function index were compared between the two groups to observe the occurrence of adverse reactions, and to compare the FEV1 / FVC+ FEV1% predicted values between the two groups. The number of acute exacerbations was greater than that of the occurrence and the effective clinical control rate. Results compared with the control group, after 6 months of intervention, The proportion of first-level services in the intervention group decreased by 25%; the incidence of adverse reactions was reduced by 7.82; the incidence of acute exacerbation was equal to that of the incidence rate by 7.81; the effective clinical control rate increased by 23.43% FEV1 / FVCFEV1% and the drug compliance was significantly improved. The difference was statistically significant (P 0.05). Conclusion graded pharmacological care for patients with chronic diseases of asthma and COPD can help pharmacists to find the most important services in the shortest time, and to improve the quality of pharmaceutical care and the clinical efficacy at the same time.
【作者單位】： 蘇州大學(xué)附屬第一醫(yī)院藥學(xué)部;
【基金】：國家自然科學(xué)基金資助項(xiàng)目(81300026) 江蘇省衛(wèi)生計(jì)生委預(yù)防醫(yī)學(xué)科研課題項(xiàng)目資助(Y2015068) 蘇州市科技局應(yīng)用基礎(chǔ)研究醫(yī)療衛(wèi)生項(xiàng)目資助(SYS201541);蘇州市科技局常州四藥項(xiàng)目資助(SYSD2016147) 百特生物藥學(xué)基金課題資助項(xiàng)目資助(201514)
【分類號】：R562.25;R563.9

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本文編號：1821779