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超聲心動圖評價肺栓塞患者右心室功能的研究

發(fā)布時間:2018-04-23 00:01

  本文選題:超聲心動圖 + Tei指數(shù); 參考:《廣西醫(yī)科大學(xué)》2012年碩士論文


【摘要】:目的:運用二維超聲心動圖(two-dimensional echocardiography,2DE)、組織多普勒成像技術(shù)(tissue Doppler imaging, TDI)、實時三維超聲心動圖(real-time three dimensional echocardiography, RT-3DE)評估肺栓塞患者右心室功能,探討不同方法在臨床評價肺栓塞患者右心室功能的準(zhǔn)確性、敏感性及優(yōu)越性。 方法:28例肺栓塞患者,男性16例,女性12例,平均年齡(56.77±11.01)歲,根據(jù)預(yù)期的肺栓塞相關(guān)早期病死率進行危險分層為高危、中危、低危3個組,每組分別為8、12和8例;正常對照組30例,男性18例,女性12例,平均年齡(54.83±9.57)歲,經(jīng)詳細(xì)詢問病史、體格檢查、心電圖及心臟超聲檢查證實為健康人。所有研究對像行2DE、TDI和RT-3DE檢查,測算其右心常規(guī)超聲指標(biāo)、右心室Tei指數(shù)、右心室舒張期末容積(right ventricular end-diastolic volume, RVEDV)、右心室收縮期末容積(right ventricular end-systolic volume, RVESV)、右心室每搏輸出量(right ventricular stroke volume, RVSV)及右心室射血分?jǐn)?shù)(right ventricular ejection fraction, RVEF)。應(yīng)用SPSS 13.0 for windows統(tǒng)計軟件進行分析,多組間比較采用方差分析,組間兩兩比較采用SNK檢驗,檢驗水準(zhǔn)a=0.05。 結(jié)果:與對照組相比,肺栓塞患者高危組具有較明顯的右心擴大及肺動脈高壓征象,其右室Tei指數(shù)、RVEDV、RVESV明顯增大(P0.05),RVEF明顯減小(P0.05);中危組盡管沒有明顯右心增大,但其右室Tei指數(shù)、RVEDV、RVESV、RVEF均已出現(xiàn)異常(P0.05);低危組的右室Tei指數(shù)、RVEDV、RVESV、RVEF與對照組相比,差異無統(tǒng)計學(xué)意義(P0.05)。中危組的右室Tei指數(shù)、RVEDV、RVESV大于低危組而小于高危組;中危組的RVEF小于低危組而大于高危組。 結(jié)論:肺栓塞患者的右心室功能可正常,亦可不同程度受損;TDI技術(shù)測量右室Tei指數(shù)和RT-3DE測量RVEF均可客觀、準(zhǔn)確、較敏感反映肺栓塞患者右室功能變化,是評價其右室功能的較好指標(biāo)。
[Abstract]:Objective: to evaluate the right ventricular function in patients with pulmonary embolism by two-dimensional echocardiography, tissue Doppler imaging and real-time three dimensional echocardiography (RT-3DEE). To evaluate the accuracy, sensitivity and superiority of different methods in evaluating right ventricular function in patients with pulmonary embolism. Methods Twenty eight patients with pulmonary embolism, 16 males and 12 females, with an average age of 56.77 鹵11.01 years, were classified as high risk, moderate risk and low risk group according to the expected early mortality of pulmonary embolism. 30 normal control group (male 18, female 12, mean age 54.83 鹵9.57), were confirmed to be healthy by detailed inquiry of medical history, physical examination, electrocardiogram and echocardiography. All the subjects were examined by 2DED TDI and RT-3DE, and the right ventricular Tei index and the normal echocardiographic index of the right heart were measured. Right ventricular end-diastolic volume, right ventricular end-diastolic volume, right ventricular end-systolic volume, right ventricular stroke volume, right ventricular stroke volume and right ventricular ejection fractionation. The statistical software of SPSS 13.0 for windows was used to analyze, the analysis of variance was used in the comparison between groups, and the SNK test was used to test the level of A0.05. Results: compared with the control group, the high risk group of pulmonary embolism had obvious signs of right heart enlargement and pulmonary hypertension, and the right ventricular Tei index (RVEDVV) increased significantly (P 0.05) and the RVEF decreased significantly (P 0.05), while in the middle risk group, the right heart did not increase significantly. However, the RVEF of RVEDVV, RVESVV, RVEF of RVEDVV, RVESVV, RVEF of RVEDVV, RVESVV, RVEF of RVEDVV, RVESVV, RVEVEF of RVEDVV, RVESVV, RVEF of RVEDVV, RVESVV, RVEF of RVEVV VEF in RVEDVV RV DVV RVESV in moderate risk group was higher than that in low risk group but smaller than that in high risk group, and RVEF in middle risk group was lower than that in low risk group but larger than that in high risk group. Conclusion: the right ventricular function in patients with pulmonary embolism is normal, and the right ventricular Tei index and RVEF measured by RT-3DE can be objective and accurate, which can reflect the changes of right ventricular function in patients with pulmonary embolism. It is a good index to evaluate the right ventricular function.
【學(xué)位授予單位】:廣西醫(yī)科大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2012
【分類號】:R563.5

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