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插管后氣管狹窄介入治療的療效及其影響因素分析

發(fā)布時(shí)間:2018-04-22 11:50

  本文選題:氣管狹窄 + 氣管插管; 參考:《中國呼吸與危重監(jiān)護(hù)雜志》2017年04期


【摘要】:目的探討插管后氣管狹窄呼吸介入治療的療效并分析其相關(guān)影響因素。方法回顧性分析2010年2月至2015年3月廣州醫(yī)科大學(xué)附屬第一醫(yī)院診治的69例插管后氣管狹窄患者的臨床資料,通過查閱病歷和電話隨訪1年以上,分析呼吸介入治療插管后氣管狹窄的療效,應(yīng)用多元Logistic回歸模型分析其療效的影響因素。結(jié)果 69例氣管插管后氣管狹窄病例中,男36例,女33例;中位年齡44歲;共接受呼吸介入治療275次,平均3.98次/例。患者經(jīng)呼吸介入治療后氣促癥狀緩解,ATS氣促評分由(2.41±0.76)分降至(0.65±0.62)分(P0.01),氣管內(nèi)徑由(4.24±2.05)mm增加至(10.57±3.14)mm(P0.01)。呼吸介入治療的近期有效率為92.8%(64/69),治療后1個(gè)月、3個(gè)月、1年內(nèi)再狹窄的比例分別為56.5%、26.1%和36.2%。多元Logistic回歸分析顯示合并糖尿病(OR=2.819,95%CI 1.973~4.062)、氣促評分3分(OR=13.816,95%CI 5.848~32.641);氣管狹窄段直徑4.5 mm(OR=7.482,95%CI 4.015~13.943)、狹窄分級≥4級(OR=3.815,95%CI 2.258~6.447)、氣管上段狹窄(OR=5.173,95%CI 3.218~8.316)與呼吸介入治療后再狹窄的發(fā)生率呈正相關(guān)。結(jié)論氣管插管后氣管狹窄介入治療的總體療效欠佳,復(fù)發(fā)率仍較高。氣管狹窄程度高、合并糖尿病及氣管上段狹窄是影響呼吸介入治療療效的重要因素。
[Abstract]:Objective to investigate the effect of interventional therapy for tracheal stenosis after intubation and analyze its related factors. Methods the clinical data of 69 patients with tracheal stenosis after intubation in the first affiliated Hospital of Guangzhou Medical University from February 2010 to March 2015 were analyzed retrospectively. Objective: to analyze the effect of respiratory interventional therapy on tracheal stenosis after intubation, and to analyze the influencing factors by multiple Logistic regression model. Results among 69 cases of tracheal stenosis after tracheal intubation, 36 cases were males and 33 cases were females, the median age was 44 years old, 275 times of respiratory interventional therapy (mean 3.98 times / case). After respiratory interventional therapy, the score of ATS for relief of dyspnea symptoms decreased from 2.41 鹵0.76 to 0.65 鹵0.62min (P 0.01), and the trachea diameter increased from 4.24 鹵2.05)mm to 10.57 鹵3.14mm / L P0.01a. The short term effective rate of respiratory interventional therapy was 92.8% and the proportion of restenosis within 1 month, 3 months and 1 year after treatment was 56. 5% and 36. 2%, respectively. Multiple Logistic regression analysis showed that there was a positive correlation between the incidence of restenosis in the trachea stenosis segment (4.01595 CI 4.01543), the stenosis grade 鈮,

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