本文選題：無(wú)創(chuàng)正壓通氣　切入點(diǎn)：慢性阻塞性肺疾病急性加重期　出處：《中國(guó)現(xiàn)代藥物應(yīng)用》2016年21期

【摘要】：目的觀察慢性阻塞性肺疾病急性加重期(AECOPD)呼吸衰竭并意識(shí)障礙患者采用無(wú)創(chuàng)正壓通氣(NIPPV)治療的臨床效果。方法 72例AECOPD呼吸衰竭并意識(shí)障礙患者分為A組和B組,各36例。A組采用NIPPV治療,B組采用常規(guī)治療。分別于治療前、治療24 h、治療72 h時(shí)觀察兩組患者的生理指標(biāo)情況,觀察兩組患者治愈率及院內(nèi)死亡率。結(jié)果治療前,兩組患者各項(xiàng)生理指標(biāo)比較,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。治療后,A組患者治愈率88.9%高于B組的52.8%,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。A組治療24 h、治療72 h時(shí)動(dòng)脈血氧分壓(Pa O2)均高于B組,動(dòng)脈血二氧化碳分壓(Pa CO2)及心率(HR)均低于B組,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。兩組患者呼吸(RR)、院內(nèi)死亡率比較差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論 AECOPD呼吸衰竭并意識(shí)障礙患者采用NIPPV治療時(shí),具有良好的治療效果,可提升治愈率。
[Abstract]:Objective to observe the clinical effect of noninvasive positive pressure ventilation (NIPPV) in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) with respiratory failure and consciousness disorder. Methods 72 patients with AECOPD respiratory failure and consciousness disorder were divided into group A and group B. 36 cases in group A were treated with NIPPV, group B were treated with routine therapy, the physiological indexes, cure rate and hospital mortality were observed at 24 hours before treatment and 72 hours after treatment, respectively. Results before treatment, the cure rate and hospital mortality were observed. After treatment, the cure rate of group A was 88.9% higher than that of group B (52.8%). The difference was statistically significant in group A (24 h) and in group A (72 h). PaCO2) and HR) were lower in group B than those in group B. the difference was statistically significant (P 0.05). There was no significant difference in hospital mortality between the two groups. Conclusion when patients with AECOPD respiratory failure and disturbance of consciousness are treated with NIPPV, there is no significant difference in hospital mortality. It has good therapeutic effect and can improve the cure rate.
【作者單位】： 洛陽(yáng)市新區(qū)人民醫(yī)院呼吸內(nèi)科;
【分類(lèi)號(hào)】：R563.9;R563.8

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