發(fā)布時(shí)間：2018-03-29 19:30

  本文選題：醒腦靜注射液　切入點(diǎn)：腦出血　出處：《中華醫(yī)院感染學(xué)雜志》2017年17期

【摘要】：目的觀察醒腦靜注射液對(duì)腦出血合并肺部感染患者神經(jīng)功能、凝血功能和炎性指標(biāo)的影響。方法選擇2014年5月-2016年5月醫(yī)院住院治療的126例腦出血合并肺部感染患者作為研究對(duì)象,將患者隨機(jī)分為對(duì)照組和觀察組,每組各63例;對(duì)照組采用西醫(yī)常規(guī)治療,觀察組在對(duì)照組基礎(chǔ)上采用醒腦靜注射液治療,比較兩組患者的療效以及神經(jīng)功能、凝血功能和炎性指標(biāo)變化。結(jié)果觀察組總有效率為81.0%,顯著高于對(duì)照組的58.7%(χ~2=7.385,P=0.007);觀察組治療后NIHSS評(píng)分明顯升高(P0.05),GCS評(píng)分明顯下降(P0.05),與同期對(duì)照組比較差異均有統(tǒng)計(jì)學(xué)意義(P0.05);觀察組治療后纖維蛋白原水平明顯升高(P0.05),D二聚體水平明顯下降(P0.05),與同期對(duì)照組比較差異均有統(tǒng)計(jì)學(xué)意義(P0.05);兩組治療后IL-1β、IL-6、IL-8、IL-10和TNF-α水平均明顯下降(P0.05),且觀察組低于對(duì)照組水平,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論醒腦靜注射液對(duì)腦出血合并肺部感染患者進(jìn)行治療,能夠明顯提高臨床療效,改善患者神經(jīng)功能和凝血功能狀態(tài),同時(shí)抑制炎性反應(yīng),值得臨床推廣應(yīng)用。
[Abstract]:Objective to observe the effect of Xingnaojing injection on nerve function in patients with cerebral hemorrhage complicated with pulmonary infection. Methods 126 patients with intracerebral hemorrhage complicated with pulmonary infection from May 2014 to May 2016 were randomly divided into control group and observation group with 63 cases in each group. The control group was treated with routine western medicine, the observation group was treated with Xingnaojing injection on the basis of the control group, and the curative effect and nerve function of the two groups were compared. Results the total effective rate of the observation group was 81.0, which was significantly higher than that of the control group (58.7%), and the NIHSS score of the observation group was significantly higher than that of the control group (0.007%), and the NIHSS score of the observation group was significantly higher than that of the control group (P 0.05%). After treatment, the level of fibrinogen in the observation group increased significantly and the level of P0.05 D dimer decreased significantly, which was significantly different from that in the control group, and the levels of IL-10 and TNF- 偽 in the IL-1 尾 6 IL-8 and TNF- 偽 decreased significantly after treatment, and the levels of TNF- 偽 in the observation group were lower than those in the control group. Conclusion Xingnaojing injection in treating patients with cerebral hemorrhage complicated with pulmonary infection can obviously improve the clinical efficacy, improve the neurological function and coagulation function of the patients, and inhibit inflammatory reaction. It is worth popularizing and applying in clinic.
【作者單位】： 南陽(yáng)市中心醫(yī)院神經(jīng)外科;
【分類(lèi)號(hào)】：R563.1;R743.34

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1 高建凱;王景輝;;醒腦靜注射液治療支氣管炎合并肺性腦病28例[J];河南中醫(yī);2012年05期

2 陳國(guó)棟;汪沛沛;胡志峰;;醒腦靜治療急性上呼吸道感染的療效觀察[J];遼寧醫(yī)學(xué)院學(xué)報(bào);2012年06期

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本文編號(hào)：1682525