本文選題：睡眠呼吸暫停　切入點：阻塞性　出處：《中國全科醫(yī)學(xué)》2017年35期 　論文類型：期刊論文

【摘要】：目的評價STOP-Bang問卷(SBQ)用于篩查重疊綜合征(OS)的臨床價值。方法選取2015年6月—2017年4月在無錫市人民醫(yī)院呼吸科就診且疑診OS的慢性阻塞性肺疾病(COPD)患者320例,患者均接受多導(dǎo)睡眠監(jiān)測(PSG)檢查,并同時在專業(yè)醫(yī)護人員指導(dǎo)下填寫SBQ,分析兩者相關(guān)性。并根據(jù)睡眠呼吸暫停低通氣指數(shù)(AHI)將患者分為5≤AHI≤15、15AHI≤30、AHI30 3組,分析SBQ預(yù)測OS的靈敏度、特異度、陽性預(yù)測值和陰性預(yù)測值,并繪制受試者工作特征(ROC)曲線。結(jié)果 SBQ與年齡、第1秒用力呼氣末容積(FEV1)/用力肺活量(FVC)、混合性呼吸暫停指數(shù)(MAI)無直線相關(guān)關(guān)系(r_s=0.061,P=0.279;r_s=-0.910,P=0.102;r_s=0.181,P=0.511);SBQ與體質(zhì)指數(shù)(BMI)、AHI、低通氣指數(shù)(HI)、阻塞性睡眠呼吸暫停指數(shù)(OAI)、中樞性呼吸暫停指數(shù)(CAI)、氧減指數(shù)(ODI)呈正相關(guān)(r_s=0.032,P0.001;r_s=0.538,P0.001;r_s=0.403,P0.001;r=0.526,P0.001;r_s=0.265,P0.001;r_s=0.506,P0.001);SBQ與FEV1呈負(fù)相關(guān)(r_s=-0.130,P=0.016)。SBQ診斷OS的靈敏度為99.2%,特異度為85.6%,陽性預(yù)測值為80.1%,陰性預(yù)測值為99.4%。SBQ預(yù)測5≤AHI≤15的OS患者的ROC曲線下面積(AUC)為0.915(0.737,0.957),最佳診斷界值為2分;預(yù)測15AHI≤30的OS患者的AUC為0.861(0.812,0.910),最佳診斷界值為5分;預(yù)測AHI30的OS患者的AUC為0.769(0.641,0.895),最佳診斷界值為6分。結(jié)論篩查OS時,SBQ與PSG主要檢查指標(biāo)具有相關(guān)性,是一個較好的篩查和預(yù)測OS的工具,值得臨床推廣。
[Abstract]:Objective to evaluate the clinical value of STOP-Bang questionnaire for screening overlap syndrome. Methods 320 patients with chronic obstructive pulmonary disease (COPD) with suspected OS were selected from June 2015 to April 2017 in Department of Respiratory, Wuxi people's Hospital. All patients were examined with PSG, and at the same time, the patients were filled in SBQs under the guidance of professional medical staff, and the correlation between them was analyzed. According to the sleep apnea hypopnea index (AHII), the patients were divided into 5 鈮，

本文編號：1604217