本文選題：重癥肺炎　切入點：老年　出處：《山東醫(yī)藥》2017年12期 　論文類型：期刊論文

【摘要】：目的探討老年重癥肺炎患者預(yù)后的影響因素。方法選擇老年重癥肺炎患者428例,根據(jù)入院14天病情轉(zhuǎn)歸情況分為遷延惡化組193例、好轉(zhuǎn)組235例,對兩組一般臨床因素(如性別、年齡、基礎(chǔ)心率、平均動脈壓、原發(fā)病情況)、相關(guān)生化指標[治療前和治療1、3天血清膽堿酯酶(S-ChE)、過氧化脂質(zhì)(LPO)、肝功能(ALT、AST)、腎功能(Scr、BUN)、血常規(guī)(WBC、PLT)、凝血功能(APTT)]、病情診治情況[急性生理與慢性健康評分Ⅱ(APACHEⅡ)、多臟器功能障礙綜合征(MODS)評分、氧合指數(shù)(PaO_2/FiO_2)、病原微生物及機械通氣治療情況]進行對比分析。將兩組上述因素比較有統(tǒng)計學(xué)差異的指標進行二元Logistic多因素回歸分析,篩選老年重癥肺炎患者預(yù)后的危險因素。結(jié)果兩組一般臨床因素各指標比較P均0.05。生化指標相關(guān)因素中,兩組血清S-Ch E、LPO及有S-Ch E降低趨勢者、有LPO增高趨勢者例數(shù)比較P均0.05,其余指標比較P均0.05。重癥肺炎相關(guān)因素中,兩組APACHEⅡ評分、MODS評分、PaO_2/FiO_2比較P均0.05,其余指標比較P均0.05。二元Logistic多因素回歸分析顯示,血清S-Ch E水平降低、LPO水平升高及APACHEⅡ評分、MODS評分升高者預(yù)后相對較差。結(jié)論APACHEⅡ評分、MODS評分及血清S-ChE、LPO水平是老年重癥肺炎患者預(yù)后的影響因素。
[Abstract]:Objective to investigate the prognostic factors of elderly patients with severe pneumonia. Methods 428 elderly patients with severe pneumonia were divided into two groups according to the prognosis of 14 days after admission: 193 cases in the prolonged exacerbation group and 235 cases in the improved group. The general clinical factors (such as sex) in the two groups were analyzed. Age, basic heart rate, mean arterial pressure, Serum cholinesterase S-Chem, Lipid peroxide LPOP, liver function alt ASTN, Renal function Scr-BUNT, Blood routine examination WBCClP, Coagulation function APTTT], diagnosis and treatment of the disease [Acute Physiology and chronic Health scale 鈪, related biochemical indexes [serum cholinesterase S-Chem, lipid peroxidation, liver function, liver function, Scr-BUNT, blood routine test, coagulation function, APTTT], serum cholinesterase S-Chem, lipid peroxide, liver function, liver function, liver function and kidney function. Apache 鈪，

本文編號：1576494