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腎臟清除率對(duì)重癥肺部感染患者機(jī)體內(nèi)穩(wěn)可信谷濃度影響的研究

發(fā)布時(shí)間:2018-03-04 20:04

  本文選題:穩(wěn)可信 切入點(diǎn):谷濃度 出處:《中國(guó)地方病防治雜志》2017年07期  論文類(lèi)型:期刊論文


【摘要】:正近些年來(lái),腎清除率增加對(duì)抗菌藥血藥濃度的影響逐漸受到關(guān)注。有研究稱(chēng),重癥感染患者可能會(huì)發(fā)生腎清除率增加,從而影響抗菌治療效果[1]。因此了解腎清除率對(duì)穩(wěn)可信血藥濃度的影響對(duì)于指導(dǎo)臨床合理用藥非常重要。本研究分析了老年重癥肺部感染患者血液中穩(wěn)可信谷濃度,旨在探討腎清除率對(duì)于谷濃度的影響。1資料與方法1.1納入與排除標(biāo)準(zhǔn)納入標(biāo)準(zhǔn):(1)符合重癥肺炎診斷的患者;(2)MRSA感染并接受穩(wěn)可信治療的患者;(3)患者年齡≥
[Abstract]:In recent years, the effect of increased renal clearance on the blood concentration of antimicrobial agents has become increasingly concerned. Some studies have suggested that patients with severe infections may have increased renal clearance. Therefore, it is very important to understand the effect of renal clearance rate on stable and credible serum drug concentration in order to guide the rational use of drugs in clinic. This study analyzed the stable and credible valley concentration in blood of elderly patients with severe pulmonary infection. Objective to investigate the effect of renal clearance on valley concentration. 1 data and methods 1.1 inclusion and exclusion criteria: 1) age 鈮,

本文編號(hào):1567095

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