本文關(guān)鍵詞： 清金化痰湯 肺熱壅盛 AECOPD　出處：《廣州中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:觀察清金化痰湯加減聯(lián)合西醫(yī)治療肺熱壅盛型慢性阻塞性肺病急性加重(AECOPD)對(duì)比單純西醫(yī)療法,在治療前后CAT評(píng)分、癥狀體征評(píng)分、降鈣素原(PCT)、中性粒細(xì)胞百分比、胸片、住院時(shí)間的變化,從而對(duì)比聯(lián)合中醫(yī)湯劑治療后的臨床療效,能否在改善癥狀及縮短住院時(shí)間中發(fā)揮重要作用。方法:采用隨機(jī)、對(duì)照、前瞻性研究方法。選取符合納入標(biāo)準(zhǔn)的肺熱壅盛型AECOPD患者60例,通過隨機(jī)數(shù)字法將入組病人隨機(jī)分配至實(shí)驗(yàn)組與對(duì)照組,每組各30例。對(duì)照組接受常規(guī)西醫(yī)治療措施,具體治療方案為:0.9%氯化鈉溶液2ml+硫酸沙丁胺醇吸入溶液2ml+吸入用異丙托溴銨溶液2ml+吸入用布地奈德混懸液2ml氧氣霧化吸入,每日3次,療程為5天;0.9%氯化鈉溶液10ml+氨溴索注射液30mg靜脈推注,每天3次,5天后改用口服;0.9%氯化鈉溶液100ml+多索茶堿0.1g靜脈滴注每12小時(shí)1次療程為5天;經(jīng)驗(yàn)性使用抗生素、退熱、補(bǔ)液營(yíng)養(yǎng)支持等治療手段。實(shí)驗(yàn)組在對(duì)照組基礎(chǔ)上加用清金化痰湯加減化裁。觀察兩組在治療前后的CAT及癥狀體征評(píng)分、PCT、NEU%、胸片及住院時(shí)間,運(yùn)用SPSS22.0版軟件進(jìn)行統(tǒng)計(jì)學(xué)分析,從而對(duì)清金化痰湯治療肺熱壅盛型AECOPD的臨床療效做出系統(tǒng)評(píng)價(jià),對(duì)今后臨床上的廣泛應(yīng)用提供理論支持。結(jié)果:兩組患者治療前在性別、年齡、CAT評(píng)分、癥狀體征評(píng)分、PCT、NEU%的差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。治療后,上述數(shù)據(jù)及住院時(shí)間行組間比較可得P0.05,表明實(shí)驗(yàn)組療效優(yōu)于對(duì)照組。結(jié)果顯示,清金化痰湯在治療肺熱壅盛型AECOPD較單純西醫(yī)治療有顯著臨床效果。結(jié)論:通過對(duì)清金化痰湯聯(lián)合西醫(yī)治療肺熱壅盛型AECOPD的臨床療效觀察,證實(shí)在改善臨床癥狀、縮短住院時(shí)間等方面,清金化痰湯聯(lián)合西醫(yī)治療行之有效,值得在臨床廣泛應(yīng)用。
[Abstract]:Objective: to observe the efficacy of Qingjin Huatan decoction combined with western medicine in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD) with heat of lung heat. Before and after treatment, CAT score, symptom and sign score, procalcitonin protopril, percentage of neutrophils, chest radiography were observed. The change of hospitalization time, so as to compare the clinical effect of combined Chinese medicine decoction treatment, whether it can play an important role in improving symptoms and shortening hospital stay. Prospective study methods. Sixty patients with AECOPD with lung heat accumulation were selected and randomly assigned to the experimental group and the control group with 30 cases in each group. The patients in the control group were treated with routine western medicine, and the patients in the control group were treated with routine western medicine, and the patients in each group were randomly assigned to the experimental group and the control group. The specific treatment plan was: 2 ml sodium chloride solution 2ml salbutamol sulfate inhalation solution 2ml inhalation ipratropium bromide solution 2ml inhaled budesonide suspension 2ml oxygen atomization inhalation, 3 times a day. The course of treatment was 5 days with 0.9% sodium chloride solution 10ml ambroxol injection 30mg intravenously, and then oral sodium chloride solution 100ml doxorophylline 0.1 g intravenously injected every 12 hours for 5 days. The experimental group was treated with Qingjinhuatan decoction on the basis of the control group. The CAT, symptom and sign scores, chest film and hospitalization time of the two groups were observed before and after treatment, and the statistical analysis was carried out with SPSS22.0 software. Therefore, the clinical efficacy of Qingjin Huatan decoction in the treatment of AECOPD with lung heat obstruction was systematically evaluated, and theoretical support was provided for its wide clinical application in the future. Results: before treatment, the patients in the two groups had cat scores of gender and age. There was no significant difference in the scores of symptoms and signs between the two groups (P 0.05). After treatment, the above data and the length of stay were compared between the two groups, which indicated that the effect of the experimental group was better than that of the control group, and the results showed that there was no significant difference between the two groups. Conclusion: the clinical effect of Qingjin Huatan decoction (QJHuatang) in the treatment of AECOPD with lung heat obstruction is more significant than that of western medicine alone. Conclusion: the clinical symptoms are improved by observing the clinical effect of Qingjin Huatan decoction combined with western medicine in the treatment of AECOPD with lung heat blockage. The treatment of Qingjin Huatan decoction combined with western medicine is effective and worthy of wide clinical application.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R563.9

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