本文關鍵詞： 支氣管擴張癥 病因 肺功能 高分辨率計算機斷層掃描　出處：《鄭州大學》2017年碩士論文　論文類型：學位論文

【摘要】：目的分析支氣管擴張癥(bronchiectasis,BE)患者的臨床特點、胸部高分辨率計算機橫斷面掃描(high-resolution computed tomograpy,HRCT)及肺功能結果,以增進對BE的認識。方法收集于2015.06.01-2016.06.01收住鄭州大學第一附屬醫(yī)院的HRCT確診的BE患者301例,回顧性分析其年齡、性別、起病年齡、病因、臨床癥狀、胸部HRCT、肺功能及其他資料。結果1.該病在女性的發(fā)病率(62.79%)高于男性(37.21%),而且其起病年齡(33.93±19.86)較男性(40.43±20.55)小,差異具有顯著統(tǒng)計學意義(P0.01)。2.該病最常見的臨床癥狀依次是咳嗽(84.05%)、咳痰(80.07%)、胸悶(52.6%)、咯血(42.19%)、發(fā)熱(32.56%)、胸痛(9.3%)及其他。3.特發(fā)性是BE最常見病因(62.12%),其次為結核后(19.93%)。4.左肺下葉為最常見病變部位(77.41%),累及全部肺葉的病例最多(25.91%)。5.囊狀BE患者最易出現(xiàn)典型的臨床表現(xiàn),即咳嗽、咳痰、胸悶、咯血。6.該研究中108例患者行肺功能檢查,69.44%出現(xiàn)阻塞性通氣功能障礙;75例阻塞性通氣功能障礙的患者FEV1/FVC與HRCT評分呈負相關。結論1.該病在女性的發(fā)病率高于男性。2.特發(fā)性是BE最常見病因,其次為結核后。3.囊狀BE患者的臨床表現(xiàn)最明顯,更易出現(xiàn)全肺葉受累。4.大部分BE患者出現(xiàn)阻塞性通氣功能障礙,其FEV1/FVC與HRCT評分呈現(xiàn)負相關。
[Abstract]:Objective to analyze the clinical characteristics of bronchiectasis patients, the results of high-resolution computed tomograpy HRCTs and pulmonary function in patients with bronchiectasis. Methods 301 patients with be diagnosed in the first affiliated Hospital of Zhengzhou University were collected from January to January 2015.06.01-2016.06.Methods the age, sex, onset age, etiology and clinical symptoms of be were retrospectively analyzed. Results 1. The incidence of HRCTs in women was higher than that in males (62.79) and the onset age was 33.93 鹵19.86), which was lower than that in males (40.43 鹵20.55). The most common clinical symptoms of the disease were cough 84.05, phlegm 80.07, chest tightness 52.66, hemoptysis 42.1910, fever 32.56r, chest pain 9.30.The most common etiology of be was 62.1212. The most common lesions were 77.41%, and the most common cases involving all the lobes were 25.91%. The patients with cystic be were most likely to have typical clinical manifestations. Cough, expectoration, chest tightness, Hemoptysis. 69.44% of the 108 patients with obstructive ventilation dysfunction and 75 patients with obstructive ventilation dysfunction showed negative correlation with HRCT score. Conclusion 1.The incidence of this disease in women is higher than that in men. 2. Idiopathic is the most common cause of be, The clinical manifestations of patients with cystic be were the most obvious, and the whole pulmonary lobe involvement was more likely. The majority of be patients had obstructive ventilation dysfunction, and their FEV1/FVC was negatively correlated with HRCT score.
【學位授予單位】：鄭州大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R562.22
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本文編號：1502712