體外膜肺氧合對(duì)重癥患者的治療效果評(píng)價(jià)
發(fā)布時(shí)間:2018-01-30 12:55
本文關(guān)鍵詞: 體外膜肺氧合 重癥醫(yī)學(xué) ARDS 治療效果 出處:《現(xiàn)代預(yù)防醫(yī)學(xué)》2015年01期 論文類型:期刊論文
【摘要】:目的評(píng)估體外膜肺氧合對(duì)重癥患者的治療效果,為今后臨床救治重癥ARDS患者提供依據(jù)。方法選擇2008年1月-2013年3月至我院ICU救治的患者中,由于呼吸窘迫綜合癥機(jī)械通氣效果不佳進(jìn)行ECMO支持治療的重癥患者21例作為研究對(duì)象。所有患者均采用靜脈-靜脈(V-V)體外膜肺流轉(zhuǎn)模式,同時(shí)采用保護(hù)性肺通氣策略,監(jiān)測中心靜脈壓。評(píng)估治療前后患者血?dú)庵笜?biāo)、APACHEⅡ評(píng)分、SOFA評(píng)分及患者的轉(zhuǎn)歸。結(jié)果治療前患者平均Sa O2為0.81±0.03、Pa CO2為47.3±6.9,p H值為7.10±0.14,經(jīng)ECMO治療后的三項(xiàng)指標(biāo)分別為0.98±0.02、33.5±4.6及7.42±0.08,與治療前相比差異均具有統(tǒng)計(jì)學(xué)意義(P0.001);治療前患者APACHEⅡ評(píng)分為17.1±7.3,SOFA評(píng)分為7.5±2.2,經(jīng)過ECMO治療后APACHEⅡ評(píng)分為6.8±3.0、SOFA評(píng)分為6.0±1.8,治療前后相比差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。在21例接受治療的患者中,2例死亡,其余19例均順利出院,死亡率為9.52%。結(jié)論 ECMO能減輕重癥患者心肺負(fù)荷,改善患者缺氧癥狀,促進(jìn)心肺的恢復(fù),減少有關(guān)并發(fā)癥的發(fā)生。
[Abstract]:Objective to evaluate the effect of extracorporeal membrane oxygenation on severe patients. Methods from January 2008 to March 2013, we selected the patients who were treated with ICU in our hospital from January 2008 to March 2013. Twenty-one patients with severe respiratory distress syndrome who were treated with ECMO support because of poor mechanical ventilation were studied. All patients were treated with IV-VV extracorporeal membrane pulmonary flow model. At the same time, the protective lung ventilation strategy was used to monitor the central venous pressure and to evaluate the blood gas index and Apache 鈪,
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