中藥霧化聯(lián)合離子導入治療慢性阻塞性肺疾病急性加重期患者35例臨床觀察
本文關(guān)鍵詞:中藥霧化聯(lián)合離子導入治療慢性阻塞性肺疾病急性加重期患者35例臨床觀察 出處:《中醫(yī)雜志》2016年08期 論文類型:期刊論文
更多相關(guān)文章: 中藥霧化 離子導入 慢性阻塞性肺疾病 C反應(yīng)蛋白 降鈣素原
【摘要】:目的觀察中藥霧化聯(lián)合離子導入治療慢性阻塞性肺疾病急性加重期的臨床療效。方法將70例慢性阻塞性肺疾病急性加重期患者隨機分為治療組和對照組各35例。對照組給予常規(guī)西藥抗生素及解痙平喘藥治療,治療組在對照組基礎(chǔ)上加用中藥霧化及離子導入,每日1次,每次30 min,兩組均治療14天。觀察治療前后患者咳嗽、咯痰、喘息以及濕Up音癥狀體征積分,檢測肺功能及血清C反應(yīng)蛋白(CRP)與降鈣素原(PCT)水平。記錄兩組患者治療期間使用抗生素的平均天數(shù),并判定臨床療效。結(jié)果治療組35例中顯效30例,好轉(zhuǎn)3例,無效2例,總有效率為94.28%;對照組35例中顯效28例,好轉(zhuǎn)3例,無效4例,總有效率為88.57%,兩組臨床療效比較差異無統(tǒng)計學意義(P0.05)。治療組平均抗生素使用天數(shù)明顯少于對照組(P0.05)。兩組治療后喘息、咳嗽、咯痰及濕Up音癥狀體征積分較治療前顯著降低(P0.01);治療后治療組咳嗽、咯痰積分較對照組改善明顯(P0.05)。治療后兩組組間肺功能比較差異無統(tǒng)計學意義(P0.05)。兩組患者治療后CRP、PCT較本組治療前顯著降低(P0.01),且治療組較對照組降低更明顯(P0.05)。結(jié)論中藥霧化及離子導入能顯著改善患者臨床癥狀,降低炎癥指標,減少抗生素的應(yīng)用。
[Abstract]:Objective to observe the clinical effect of Chinese medicine atomization combined with iontophoresis on acute exacerbation of chronic obstructive pulmonary disease. Methods 70 patients with acute exacerbation of chronic obstructive pulmonary disease were randomly divided into treatment group and control group. The control group was treated with routine western medicine antibiotics and antispasmodic drugs. The treatment group in the control group on the basis of adding Chinese medicine atomization and iontophoresis, once a day, 30 minutes each time, both groups were treated for 14 days. Observe the patients before and after treatment cough, sputum. The scores of symptoms and signs of wheezing and wet up were measured. The pulmonary function and serum levels of C-reactive protein (CRP) and procalcitonin (PCT) were measured. The average days of antibiotic use during treatment were recorded. Results in the treatment group, there were 30 cases of remarkable effect, 3 cases of improvement and 2 cases of ineffective. The total effective rate was 94.2828. In the control group, there were 28 cases with remarkable effect, 3 cases with improvement and 4 cases with no effect. The total effective rate was 88.57%. There was no significant difference in clinical efficacy between the two groups. The average days of antibiotic use in the treatment group was significantly less than that in the control group (P 0.05). After treatment, the two groups were wheezing and coughing. The score of symptoms and signs of phlegm and wet up was significantly lower than that before treatment (P 0.01). After treatment, the scores of cough and sputum in the treatment group were significantly improved than those in the control group (P 0.05). There was no significant difference in pulmonary function between the two groups after treatment. CRP was found in the two groups after treatment. PCT was significantly lower than that before treatment, and that of the treatment group was significantly lower than that of the control group. Conclusion Chinese medicine atomization and iontophoresis can significantly improve the clinical symptoms of the patients. Reduce the inflammation index, reduce the use of antibiotics.
【作者單位】: 淮北市中醫(yī)院;安徽中醫(yī)藥大學第一附屬醫(yī)院;
【基金】:國家中醫(yī)藥管理局中醫(yī)藥防治重大疑難疾病臨床服務(wù)能力建設(shè)項目(2014mzfyjs006) 安徽省省級中醫(yī)發(fā)展專項(2014ZY69)
【分類號】:R563.9
【正文快照】: 慢性阻塞性肺疾病(簡稱慢阻肺)急性加重是指患者癥狀出現(xiàn)超越日常狀態(tài)的持續(xù)惡化,患者短期內(nèi)出現(xiàn)咳嗽、咯痰、氣促和(或)喘息等癥狀加重,痰量較前增多,可伴肺功能減退及炎癥因子C反應(yīng)蛋白(CRP)與降鈣素原(PCT)升高的表現(xiàn)[1]。中藥離子導入治療是物理治療方法之一,是結(jié)合中藥穴
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