本文關鍵詞：鹽酸氣體吸入致急性呼吸窘迫綜合征1例報道　出處：《上海交通大學學報(醫(yī)學版)》2015年12期 　論文類型：期刊論文

  更多相關文章： 雙相水平氣道正壓通氣 吡非尼酮 急性呼吸窘迫綜合征

【摘要】：目的探討鹽酸氣體吸入引起的急性呼吸窘迫綜合征(ARDS)臨床特點及治療方法。方法報道1例雙相水平氣道正壓通氣(BIPAP)聯(lián)合吡非尼酮(PFD)治療鹽酸氣體吸入致ARDS患者的臨床資料,復習文獻探討治療特點。結果男性患者,33歲,因吸入濃鹽酸氣體后出現(xiàn)咳嗽、咳痰伴胸悶、氣促就診。CT示兩肺彌漫性改變,手指脈搏血氧飽和度75%,以"吸入性肺炎,ARDS"收治入院,經(jīng)BIPAP輔助通氣、PFD抗纖維化等治療后患者氧合改善,臨床癥狀好轉(zhuǎn),兩肺纖維灶減少。結論早期BIPAP的應用可以顯著降低ARDS患者的插管率以及病死率。ARDS纖維化期予以PFD可以防止甚至逆轉(zhuǎn)纖維化。
[Abstract]:Objective to investigate the hydrochloric acid gas inhalation induced acute respiratory distress syndrome (ARDS) clinical characteristics and treatment methods 1 cases reported bi level positive airway pressure ventilation (BIPAP) combined with pirfenidone (PFD) treatment of HCl gas inhalation clinical data of patients with ARDS induced by the literature review on the treatment of male patients. Results 33. Old, due to inhalation of hydrochloric acid gas after the cough, expectoration and chest tightness, shortness of breath, treatment.CT showed diffuse pulmonary changes two, 75% finger pulse oximetry, with aspiration pneumonia, ARDS admitted by BIPAP assisted ventilation, improve the oxygenation in patients with PFD anti fibrosis after treatment, clinical symptoms improved, two lung fiber lesions reduced. Conclusion early application of BIPAP can significantly reduce the intubation rate and mortality rate of patients with ARDS.ARDS PFD to fibrosis stage may prevent and even reverse fibrosis.

【作者單位】： 上海交通大學醫(yī)學院附屬仁濟醫(yī)院南院呼吸科;上海交通大學醫(yī)學院附屬仁濟醫(yī)院呼吸科;
【分類號】：R563.8
【正文快照】： 急性呼吸窘迫綜合征(acute respiratory distresssyndrome,ARDS)是以呼吸困難和進行性低氧血癥為主要臨床表現(xiàn)的急性起病的呼吸衰竭。病理生理改變以肺容量減少、肺順應性下降、通氣/血流比失調(diào)為主,晚期出現(xiàn)肺組織廣泛纖維化。該病病死率高,近半數(shù)患者最終死于頑固的低氧血癥

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1 馬臻;王尊元;沈正榮;;吡非尼酮的合成[J];中國醫(yī)藥工業(yè)雜志;2006年06期

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本文編號：1355721