超聲權(quán)重評分在甲狀腺結(jié)節(jié)良惡性鑒別診斷中的應(yīng)用價值研究
發(fā)布時間:2019-07-30 09:36
【摘要】:目的探討超聲權(quán)重評分在甲狀腺結(jié)節(jié)良惡性鑒別診斷中的應(yīng)用價值。方法選取2012年3月—2015年4月北京大學(xué)人民醫(yī)院進(jìn)行超聲檢查的甲狀腺結(jié)節(jié)患者125例為研究對象,記錄結(jié)節(jié)低回聲、邊緣不規(guī)則、邊界不清晰、暈環(huán)不均勻完整、實(shí)性結(jié)節(jié)、微鈣化、縱橫比(A/T)≥1 7項(xiàng)特征,根據(jù)各特征單獨(dú)鑒別診斷甲狀腺結(jié)節(jié)良惡性的特異度進(jìn)行權(quán)重評分,7項(xiàng)相加得到超聲權(quán)重評分。以病理檢查結(jié)果為金標(biāo)準(zhǔn),分為惡性和良性。繪制受試者工作特征曲線(ROC曲線)分析超聲權(quán)重評分鑒別診斷甲狀腺結(jié)節(jié)良惡性的價值。結(jié)果 125例患者共發(fā)現(xiàn)149個甲狀腺結(jié)節(jié),結(jié)節(jié)最大徑0.3~7.0 cm,平均(2.1±1.2)cm。術(shù)后病理檢查結(jié)果示:惡性52個,均為甲狀腺乳頭狀癌;良性97個,其中結(jié)節(jié)性甲狀腺腫86個,腺瘤9個,亞急性甲狀腺炎2個。惡性甲狀腺結(jié)節(jié)超聲權(quán)重評分為(7.3±3.8)分,良性甲狀腺結(jié)節(jié)超聲權(quán)重評分為(1.8±2.4)分,差異有統(tǒng)計(jì)學(xué)意義(Z=-7.542,P0.001)。超聲權(quán)重評分鑒別診斷甲狀腺結(jié)節(jié)良惡性ROC曲線下面積為0.869〔95%CI(0.805,0.933)〕,最佳診斷截點(diǎn)為5.5分,診斷的靈敏度、特異度、正確率、陽性預(yù)測值、陰性預(yù)測值分別為69.2%、93.8%、85.2%、37.0%、98.3%。結(jié)論超聲權(quán)重評分在鑒別診斷甲狀腺結(jié)節(jié)良惡性方面有較高的應(yīng)用價值。
[Abstract]:Objective to evaluate the value of ultrasonic weight score in differential diagnosis of benign and malignant thyroid nodules. Methods from March 2012 to April 2015, 125 patients with thyroid nodules examined by ultrasound in people's Hospital of Peking University were enrolled in this study. the characteristics of hypoecho, irregular edge, unclear boundary, uneven and complete halo ring, solid nodules, microcalcification and aspect ratio (A 鈮,
本文編號:2520815
[Abstract]:Objective to evaluate the value of ultrasonic weight score in differential diagnosis of benign and malignant thyroid nodules. Methods from March 2012 to April 2015, 125 patients with thyroid nodules examined by ultrasound in people's Hospital of Peking University were enrolled in this study. the characteristics of hypoecho, irregular edge, unclear boundary, uneven and complete halo ring, solid nodules, microcalcification and aspect ratio (A 鈮,
本文編號:2520815
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