【摘要】：目的:探討3DFSE的pc-ASL技術(shù)對橋小腦角區(qū)腫瘤術(shù)后復(fù)發(fā)的診斷價(jià)值。方法:選取21例橋小腦角區(qū)占位性病變術(shù)后患者,行常規(guī)平掃及增強(qiáng)序列,在增強(qiáng)前掃描pc-ASL序列。將pc-ASL功能圖像與增強(qiáng)后Ax 3D T1WI融合,測量異常強(qiáng)化區(qū)域及對側(cè)正常腦組織的CBF值,評價(jià)是否存在腫瘤復(fù)發(fā)。結(jié)果:全部21例手術(shù)區(qū)出現(xiàn)異常強(qiáng)化區(qū)患者,13例為復(fù)發(fā)。17例患者行DSC-PWI失敗,圖像無法滿足診斷需求。全部21例pc-ASL檢查成功。腫瘤復(fù)發(fā)區(qū)域的CBF值為(64.2±3.03)mL/100g/min,對側(cè)正常腦實(shí)質(zhì)的CBF值為(52.5±1.89)mL/100g/min。腫瘤復(fù)發(fā)區(qū)域的CBF值明顯高于對照側(cè)腦組織,兩者之間差異有統(tǒng)計(jì)學(xué)意義(t=12.498,P0.05)。結(jié)論:基于3DFSE的pc-ASL序列安全無創(chuàng),無需注射對比劑,磁敏感效應(yīng)影響小,可以用于評估橋小腦角區(qū)腫瘤有無術(shù)后復(fù)發(fā)。
[Abstract]:Objective: to evaluate the diagnostic value of 3DFSE pc-ASL in postoperative recurrence of cerebellopontine angle tumors. Methods: 21 patients with space-occupying lesions in cerebellopontine angle were treated with conventional plain scan and enhanced sequence, and pc-ASL sequence was scanned before enhancement. The functional images of pc-ASL were fused with enhanced Ax 3D T1WI to measure the CBF values of abnormal enhancement area and contralateral normal brain tissue, and to evaluate the existence of tumor recurrence. Results: in all 21 patients with abnormal enhancement area, 13 patients had recurrence. 17 patients failed to perform DSC-PWI and the images could not meet the diagnostic requirements. All 21 cases were examined successfully by pc-ASL. The CBF value of tumor recurrence area was (64.2 鹵3.03) mL/100g/min, and the CBF value of contralateral normal brain parenchyma was (52.5 鹵1.89) mL/100g/min.. The CBF value of tumor recurrence area was significantly higher than that of control brain tissue, and there was significant difference between the two groups (t 鈮，

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