DWI在新生兒低血糖腦病中的診斷價(jià)值
發(fā)布時(shí)間：2018-11-14 12:06
【摘要】：目的:探討DWI在新生兒低血糖腦病診斷中的應(yīng)用價(jià)值。方法:回顧性分析18例經(jīng)臨床確診的新生兒低血糖患兒的臨床及MRI資料,所有患兒均行常規(guī)T1WI、T2WI及DWI檢查,4例嚴(yán)重低血糖患兒另行氫質(zhì)子磁共振波譜(1 H-MRS)檢查。結(jié)果:MRI顯示低血糖腦病呈彌漫性腦損傷改變,主要累及頂枕部16例,占88.89%(16/18);胼胝體壓部12例,占66.67%(12/18);視輻射9例,占50%(9/18);內(nèi)囊后肢8例,占44.44%(8/18)。額葉(4/18)、顳葉(3/18)、丘腦(3/18)及腦干(1/18)等部位亦累及。病變多呈稍長(zhǎng)T1、稍長(zhǎng)T2信號(hào),DWI呈明顯高信號(hào)。DWI異常信號(hào)的出現(xiàn)早于常規(guī)MRI序列,顯示病灶的范圍較常規(guī)序列廣泛全面,尤其對(duì)胼胝體、內(nèi)囊后肢、視輻射、丘腦等病灶的顯示較常規(guī)序列敏感。4例日齡≥9d的低血糖腦病患兒,雙側(cè)頂枕葉、基底節(jié)及視輻射出現(xiàn)短T1、短T2信號(hào),考慮為亞急性早期出血所致。4例MRS顯示損傷部位出現(xiàn)倒置乳酸(Lac)峰,谷氨酸/肌酸比值(Glx/Cr)、膽堿/肌酸比值(Cho/Cr)明顯增高,而N-乙酰天門(mén)冬氨酸/肌酸比值(NAA/Cr)明顯降低。結(jié)論:MRI是新生兒低血糖腦病首選影像檢查方法,以DWI序列優(yōu)勢(shì)最突出,不僅顯示典型腦損傷部位的高信號(hào),還能顯示不典型部位的高信號(hào)。
[Abstract]:Objective: to evaluate the value of DWI in the diagnosis of neonatal hypoglycemia encephalopathy. Methods: the clinical and MRI data of 18 neonates with hypoglycemia confirmed by clinical diagnosis were retrospectively analyzed. Routine T 1WI T 2WI and DWI examination were performed in all children, and hydrogen proton magnetic resonance spectroscopy (1 H-MRS) was performed in 4 patients with severe hypoglycemia. Results: MRI showed diffuse brain injury in hypoglycemic encephalopathy, mainly involving the parietal occipital region in 16 cases (88.89%), the corpus callosum in 12 cases (66.67%), the visual radiation in 9 cases (50%), the corpus callosum in 12 cases (66.67%), the optic radiation in 9 cases (9 / 18). There were 8 cases (44.44%) with internal capsule hindlimb (8 / 18). The frontal lobe (4 / 18), the temporal lobe (3 / 18), the thalamus (3 / 18) and the brain stem (1 / 18) are also involved. The lesions showed longer T 1, longer T 2 signal and higher signal intensity in DWI. The abnormal signal of DWI appeared earlier than that of conventional MRI sequence, and the range of lesion was more extensive than that of conventional sequence, especially for corpus callosum, posterior limb of internal capsule, visual radiation. The display of hypoglycemic encephalopathy in 4 children with hypoglycemic encephalopathy 鈮，
本文編號(hào)：2331112
[Abstract]:Objective: to evaluate the value of DWI in the diagnosis of neonatal hypoglycemia encephalopathy. Methods: the clinical and MRI data of 18 neonates with hypoglycemia confirmed by clinical diagnosis were retrospectively analyzed. Routine T 1WI T 2WI and DWI examination were performed in all children, and hydrogen proton magnetic resonance spectroscopy (1 H-MRS) was performed in 4 patients with severe hypoglycemia. Results: MRI showed diffuse brain injury in hypoglycemic encephalopathy, mainly involving the parietal occipital region in 16 cases (88.89%), the corpus callosum in 12 cases (66.67%), the visual radiation in 9 cases (50%), the corpus callosum in 12 cases (66.67%), the optic radiation in 9 cases (9 / 18). There were 8 cases (44.44%) with internal capsule hindlimb (8 / 18). The frontal lobe (4 / 18), the temporal lobe (3 / 18), the thalamus (3 / 18) and the brain stem (1 / 18) are also involved. The lesions showed longer T 1, longer T 2 signal and higher signal intensity in DWI. The abnormal signal of DWI appeared earlier than that of conventional MRI sequence, and the range of lesion was more extensive than that of conventional sequence, especially for corpus callosum, posterior limb of internal capsule, visual radiation. The display of hypoglycemic encephalopathy in 4 children with hypoglycemic encephalopathy 鈮，
本文編號(hào)：2331112
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