Gd-EOB-DTPA （釓塞酸二鈉注射液）對(duì)肝臟病變的檢出價(jià)值：磁共振平掃與Gd-EOB-DTPA增強(qiáng)掃描的對(duì)比研究
發(fā)布時(shí)間：2018-11-06 17:09
【摘要】：題目：普美顯(釓塞酸二鈉注射液)對(duì)肝臟病變的檢出價(jià)值：磁共振平掃與普美顯增強(qiáng)掃描的對(duì)比研究 目的：本研究的目的是比較使用普美顯增強(qiáng)后的肝細(xì)胞期與磁共振平掃及普美顯增強(qiáng)掃描其它動(dòng)態(tài)時(shí)相所發(fā)現(xiàn)肝臟病灶的敏感性。設(shè)計(jì)：回顧性研究 材料和方法：收集所有行MRI平掃及普美顯對(duì)比增強(qiáng)的肝病患者的磁共振圖像資料。采用雙盲法,3位閱片者在不同的環(huán)境下分別閱讀不同序列的圖像,并記錄下病變的數(shù)目、部位及大小等特征。為了避免記憶產(chǎn)生的偏差,將平掃、增強(qiáng)掃描動(dòng)脈期以及肝細(xì)胞期分別間隔一周后再給閱片者閱讀。當(dāng)每個(gè)患者完成檢查后,3位閱片者一起再次仔細(xì)的閱片然后確定病灶數(shù)目,建立一個(gè)參考標(biāo)準(zhǔn)。病人的臨床資料和報(bào)告也要考慮,還要參考以前的學(xué)者的研究。病灶數(shù)目,部位及磁共振的其它一些發(fā)現(xiàn)被認(rèn)為是建立參考標(biāo)準(zhǔn)最有價(jià)值的參數(shù)。閱片者依照參考標(biāo)準(zhǔn)將每位患者的磁共振圖像進(jìn)行閱片分析得出不同磁共振掃描序列及方法所發(fā)現(xiàn)病灶的敏感性。最后,運(yùn)用統(tǒng)計(jì)分析軟件SPSS16.0進(jìn)行統(tǒng)計(jì)分析,比較磁共振平掃和使用普美顯對(duì)比增強(qiáng)后不同時(shí)相所發(fā)現(xiàn)病灶的敏感性差異,統(tǒng)計(jì)學(xué)方法使用Wilcoxon秩和檢驗(yàn),設(shè)定P0.05差異有統(tǒng)計(jì)學(xué)意義。 結(jié)果：使用普美顯對(duì)比增強(qiáng)后的肝細(xì)胞期比磁共振平掃及普美顯增強(qiáng)掃描其它動(dòng)態(tài)時(shí)相發(fā)現(xiàn)了更多的病灶。普美顯增強(qiáng)后的肝細(xì)胞期所發(fā)現(xiàn)的病灶的敏感性與參考標(biāo)準(zhǔn)相比較,差異沒(méi)有統(tǒng)計(jì)學(xué)意義；但是磁共振平掃及普美顯增強(qiáng)掃描后的其它動(dòng)態(tài)時(shí)相與參考標(biāo)準(zhǔn)相比較,差異有統(tǒng)計(jì)學(xué)意義。 結(jié)論：在發(fā)現(xiàn)肝臟病灶方面,普美顯磁共振增強(qiáng)掃描肝細(xì)胞期比磁共振平掃及普美顯磁共振增強(qiáng)掃描其它動(dòng)態(tài)時(shí)相具有更高敏感性。
[Abstract]:Topic: the value of promestrine (gadolinium disodium injection) in the detection of hepatic lesions: a comparative study of plain MRI and prednisone contrast study objective: this study was to compare the liver with prednisone. Sensitivity of cell phase and Mr plain scan and PFM enhancement to other dynamic phases in detecting liver lesions. Design: retrospective study materials and methods: MRI images were collected from all patients with liver disease who underwent MRI plain scan and plain contrast enhancement. Using the double blind method, the three film-readers read the images of different sequences in different environments, and recorded the number, location and size of the lesions. In order to avoid the deviation of memory, scan, enhance the arterial phase and hepatocyte phase one week interval and then give the reader reading. After each patient has completed the examination, the three radiographers carefully read the film again and then determine the number of lesions and establish a reference standard. Patient clinical data and reports should also be considered, as well as previous studies by scholars. The number, location and other findings of MRI are considered to be the most valuable parameters for establishing reference criteria. According to the reference criteria, the radiographs of each patient were analyzed to determine the sensitivity of different MRI sequences and methods. Finally, statistical analysis software SPSS16.0 was used to compare the sensitivity differences between plain MRI and plain contrast enhancement. Wilcoxon rank sum test was used for statistical analysis. Set P0.05 difference was statistically significant. Results: more lesions were found in the hepatocyte phase after contrast enhancement than that in the normal MRI and other dynamic phase. There was no significant difference between the sensitivity of the liver cell phase and the reference criteria. However, there were significant differences between the other dynamic phase and the reference standard. Conclusion: in the detection of hepatic lesions, the phase of hepatocytes on Mr enhanced Mr is more sensitive than that on plain MRI and other dynamic phases.
【學(xué)位授予單位】：中南大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R445.2
本文編號(hào)：2314918
[Abstract]:Topic: the value of promestrine (gadolinium disodium injection) in the detection of hepatic lesions: a comparative study of plain MRI and prednisone contrast study objective: this study was to compare the liver with prednisone. Sensitivity of cell phase and Mr plain scan and PFM enhancement to other dynamic phases in detecting liver lesions. Design: retrospective study materials and methods: MRI images were collected from all patients with liver disease who underwent MRI plain scan and plain contrast enhancement. Using the double blind method, the three film-readers read the images of different sequences in different environments, and recorded the number, location and size of the lesions. In order to avoid the deviation of memory, scan, enhance the arterial phase and hepatocyte phase one week interval and then give the reader reading. After each patient has completed the examination, the three radiographers carefully read the film again and then determine the number of lesions and establish a reference standard. Patient clinical data and reports should also be considered, as well as previous studies by scholars. The number, location and other findings of MRI are considered to be the most valuable parameters for establishing reference criteria. According to the reference criteria, the radiographs of each patient were analyzed to determine the sensitivity of different MRI sequences and methods. Finally, statistical analysis software SPSS16.0 was used to compare the sensitivity differences between plain MRI and plain contrast enhancement. Wilcoxon rank sum test was used for statistical analysis. Set P0.05 difference was statistically significant. Results: more lesions were found in the hepatocyte phase after contrast enhancement than that in the normal MRI and other dynamic phase. There was no significant difference between the sensitivity of the liver cell phase and the reference criteria. However, there were significant differences between the other dynamic phase and the reference standard. Conclusion: in the detection of hepatic lesions, the phase of hepatocytes on Mr enhanced Mr is more sensitive than that on plain MRI and other dynamic phases.
【學(xué)位授予單位】：中南大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R445.2
【參考文獻(xiàn)】
相關(guān)期刊論文 前2條
1 Meng-Su Zeng;Hui-Yi Ye;Liang Guo;Wei-Jun Peng;Jian-Ping Lu;Gao-Jun Teng;Josy Breuer;Yi Huan;Ping Li;Jian-Rong Xu;Chang-Hong Liang;;Gd-EOB-DTPA-enhanced magnetic resonance imaging for focal liver lesions in Chinese patients:a multicenter,open-label,phase Ⅲ study[J];Hepatobiliary & Pancreatic Diseases International;2013年06期
2 Sith Phongkitkarun;Kuruwin Limsamutpetch;Penampai Tannaphai;Janjira Jatchavala;;Added value of hepatobiliary phase gadoxetic acid-enhanced MRI for diagnosing hepatocellular carcinoma in high-risk patients[J];World Journal of Gastroenterology;2013年45期
，本文編號(hào)：2314918
本文鏈接：http://sikaile.net/yixuelunwen/fangshe/2314918.html
最近更新
教材專著
