經(jīng)腫塊周圍皮下與經(jīng)腫塊周圍腺體內(nèi)注射超聲造影劑檢測乳腺癌前哨淋巴結(jié)的對比研究
[Abstract]:Objective to investigate the best contrast media injection site and its clinical value for detecting sentinel lymph node (SLN) in breast cancer by contrast-enhanced ultrasonography. Methods 65 patients with breast cancer were treated by subcutaneous and intraglandular injection of ultrasound contrast media respectively. The contrast enhancement of axillary lymph nodes was observed and recorded. The final results were compared with methylene blue staining and pathology. Result 1. In this study, 79 cases (86.81%) of SLN57 were detected by subcutaneous injection of ultrasound contrast agent around the tumor, and 58.24% (53 / 91) by intraglandular injection of SLN. There was significant difference in SLN detection between the two groups (P0.05). 2. The accuracy, sensitivity, specificity and specificity of SLN metastasis were 88.61% (70 / 79), 94.92% (56 / 59) and 70.00% (14 / 20), respectively. The accuracy, sensitivity and specificity of intraglandular injection echocardiography in detecting SLN were 86.79% (46 / 53), 82.50% (33 / 40) and 100% (13 / 13), respectively. There was no significant difference between sensitivity and specificity (P0.05). 3. The enhancement time of SLN was shorter than that of intraglandular injection, and the difference was statistically significant (P0.05). Conclusion 1. SLN can be detected accurately by subcutaneous CEUS around breast mass and whether it is metastasized or not. 2. After subcutaneous injection of ultrasound contrast agent into the surrounding breast masses, SLN has a high clinical value because of its rapid development, simple operation and easy control.
【學(xué)位授予單位】:寧夏醫(yī)科大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2014
【分類號】:R445.1;R737.9
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