【摘要】：目的:探討雙側(cè)基底節(jié)篩孔狀態(tài)的MRI表現(xiàn)及可能的臨床意義。方法:選取63例雙側(cè)基底節(jié)篩孔狀態(tài)患者作為病例組,并通過(guò)MRI評(píng)價(jià)其病灶形態(tài)、信號(hào)特點(diǎn);同時(shí)選取63例性別、年齡相匹配的正常志愿者作為對(duì)照組,病例組及對(duì)照組均進(jìn)行中文版簡(jiǎn)易智能狀態(tài)檢查量表(MMSE)評(píng)分;并按性別分層,研究高血壓與雙側(cè)基底節(jié)篩孔狀態(tài)的關(guān)系。結(jié)果:所有病灶集中于雙側(cè)殼核、豆?fàn)詈?且呈雙側(cè)對(duì)稱(chēng)性、篩孔狀分布;病灶在T_2WI上呈高信號(hào),T_1WI及FLAIR T_2WI上呈低信號(hào),無(wú)明確壁或膠質(zhì)增生表現(xiàn),擴(kuò)散未見(jiàn)明確受限表現(xiàn)。病例組的MMSE總評(píng)分[(26.00±1.95)分]較對(duì)照組[(28.44±1.15)分]低,且兩者間差異具有統(tǒng)計(jì)學(xué)意義(Z=-7.15,P0.001)。分層χ2檢驗(yàn)結(jié)果提示兩性高血壓與篩孔狀態(tài)均存在相關(guān)性(χ_M~2=19.19,P_M0.001;χ_F~2=13.60,P_F=0.001)。結(jié)論:雙側(cè)基底節(jié)篩孔狀態(tài)是一種病理改變,與患者認(rèn)知功能損傷有一定關(guān)系,高血壓可能是其中一個(gè)危險(xiǎn)因素,應(yīng)引起臨床重視。
[Abstract]:Objective: to investigate the MRI findings of bilateral basal ganglia ethmoid foramen and its possible clinical significance. Methods: 63 patients with bilateral basal ganglia ethmoidal foramen were selected as the case group, and their lesion morphology and signal characteristics were evaluated by MRI, and 63 normal volunteers with gender and age matched were selected as the control group. Case group and control group were assessed with the Chinese version of simple Intelligent State examination scale (MMSE), and the relationship between hypertension and bilateral basal ganglia ethmoidal foramen was studied by sex stratification. Results: all the lesions were concentrated in the bilateral putamen nucleus, lentiform nucleus, with bilateral symmetry and ethmoidal foramen distribution, the lesions showed high signal intensity on T_2WI, low signal on T 1WI and FLAIR T_2WI, no clear wall or glial hyperplasia, and no definite limited manifestation of diffusion. The total score of MMSE in the case group [(26.00 鹵1.95)] was lower than that in the control group [(28.44 鹵1.15)], and the difference between the two groups was statistically significant (P 0.001). The results of stratified 蠂 2 test showed that there was a correlation between hypertension and sieve foramen (蠂 _ 2 / M _ (2) ~ (19.19) / P _ (M _ (0.001); 蠂 _ (2) S / F _ (13.60) / P _ (F _ (0.001). Conclusion: the condition of bilateral basal ganglia ethmoidal foramen is a pathological change, which is related to the cognitive impairment of patients. Hypertension may be one of the risk factors, which should be paid more attention to in clinic.
【作者單位】： 南方醫(yī)科大學(xué)附屬南海醫(yī)院放射科;廣東省醫(yī)學(xué)科學(xué)院 廣東省人民醫(yī)院放射科;
【基金】：國(guó)家自然科學(xué)基金資助(81471654)
【分類(lèi)號(hào)】：R445.2;R743
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本文編號(hào)：2258090