單指數(shù)及雙指數(shù)模型DWI在肺孤立性病變診斷效能的對比研究
[Abstract]:Objective to evaluate the diagnostic efficacy of single index and double exponential models of (SPLs) in benign and malignant SPLs by conventional diffusion-weighted imaging (DWI),) with incoherent motion diffusion weighted imaging (IVIMDWI),). Methods Sixty-two patients with pathologically proved SPLs (malignant tumor 51 cases; benign lesion 11 cases) were prospectively studied. MRI plain scan DWI and IVIM-DWI.DWI scan (b value: 0 600 s / mm / 2 IVI DWI) were performed on 13 b values (0 0 / 10 1 / 10 15 ~ 20 ~ 25 / 50 ~ 20 ~ 250 ~ 50 ~ (50) ~ 80 / 150 / 150 ~ 500 ~ 800 s/mm~2) before operation. The diagnostic efficacy of ADC,D,D~* and f values was analyzed by using the (ROC) curve of operating characteristics of subjects. Results the D value of 51 malignant tumors was (0.92 鹵0.20) 脳 10 ~ (-3) mm ~ (-2) / s, the D value of benign lesions was (1.39 鹵0.36) 脳 10 ~ (-3) mm~2/s, (P0. 001), the f value of malignant tumors was (16. 02 鹵8. 7) and the f value of benign lesions was (20. 72 鹵8. 75), the difference of D value of malignant tumors was (11. 04 鹵5. 75) 脳 10 ~ (-3) mm~2/s, benign lesions (P = 0. 315), and that of malignant tumors was (11. 04 鹵5. 75) 脳 10 ~ (-3) mm~2/s,. There was no significant difference in D * value of lesion (9.79 鹵5.27) 脳 10 ~ (-3) mm~2/s, between the two groups (P < 0. 467). The ROC curve was used to analyze the area under D value of 0.858ADCBX 600 s/mm~2 curve. The best threshold of D value was 1.25 脳 10 ~ (-3) mm~2/s, sensitivity and specificity were 98.11% and 72.73%, respectively. Conclusion double index model and single index model DWI are valuable for the differential diagnosis of SPLs, and D value is the most valuable for diagnosis.
【作者單位】: 廣州醫(yī)科大學附屬第一醫(yī)院放射科;
【基金】:國家自然基金青年項目(編號:81601457) 廣東省醫(yī)學科研基金項目(編號:A2016410) 廣州市科技計劃項目(編號:201510010234) 廣州市醫(yī)藥衛(wèi)生科技項目(編號:20151A011066)
【分類號】:R445.2;R734.2
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