【摘要】：目的應(yīng)用高頻超聲篩查甲狀旁腺探討泌尿系結(jié)石與原發(fā)性甲狀旁腺功能亢進(jìn)(PHPT)的關(guān)系。方法對(duì)200例泌尿系結(jié)石患者(結(jié)石組)及200例健康體檢者(對(duì)照組)行甲狀旁腺超聲掃查,觀察甲狀旁腺顯示情況及病變;并對(duì)超聲發(fā)現(xiàn)異常者行血清甲狀旁腺激素(PTH)、血鈣、血磷檢查。結(jié)果結(jié)石組中,高頻超聲顯示甲狀旁腺136例(136/200,68.00%),發(fā)現(xiàn)甲狀旁腺腫塊28例(28/200,14.00%),腫塊體積(588.93±15.25)mm3。對(duì)照組中,高頻超聲顯示甲狀旁腺90例(90/200,45.00%),發(fā)現(xiàn)甲狀旁腺腫塊4例(4/200,2.00%),腫塊體積(84.74±12.51)mm3。兩組間高頻超聲甲狀旁腺顯示率、甲狀旁腺腫塊顯示率及腫塊體積差異均有統(tǒng)計(jì)學(xué)意義(P均0.05)。結(jié)石組12例甲狀旁腺腫塊患者為PHPT,另16例及對(duì)照組4例甲狀旁腺腫塊患者血清PTH、血鈣、血磷均正常。兩組間PHPT發(fā)生率差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)石組泌尿系結(jié)石發(fā)作≥3次者PHPT發(fā)生率(7/53,13.21%)高于結(jié)石發(fā)作3次者(5/147,3.40%;P0.05)。超聲顯示12例PHPT均為單發(fā)腫塊;7例接受甲狀旁腺切除術(shù),術(shù)后病理均為腺瘤;5例接受內(nèi)科藥物治療。結(jié)論 PHPT是反復(fù)發(fā)作泌尿系結(jié)石的一個(gè)重要且易被忽略的原因,高頻超聲可作為反復(fù)發(fā)作泌尿系結(jié)石患者甲狀旁腺的常規(guī)篩查手段。
[Abstract]:Objective to investigate the relationship between urolithiasis and primary hyperparathyroidism (PHPT) by high frequency ultrasound screening of parathyroid gland. Methods two hundred patients with urolithiasis (stone group) and 200 healthy persons (control group) were examined by ultrasonography to observe the display and pathological changes of parathyroid gland, and the serum parathyroid hormone (PTH), serum calcium was performed in those who were found abnormal by ultrasound. Blood phosphorus test. Results in the calculi group, high frequency ultrasound showed parathyroid gland in 136 cases (136 / 200%), 28 cases of parathyroid mass (28 / 200 ~ 14.00%) and mass volume (588.93 鹵15.25) mm3.. In the control group, 90 cases (45.00%) of parathyroid gland were detected by high frequency ultrasound, 4 cases (4 / 2002.00%) of parathyroid mass and (84.74 鹵12.51) mm3. of parathyroid mass were found. There were significant differences in the display rate of parathyroid gland, the display rate of parathyroid mass and the volume of mass between the two groups (P 0.05). There were 12 patients with parathyroid mass in the stone group and 16 patients with PHPT, and 4 patients with parathyroid mass in the control group. The serum levels of serum calcium and phosphorus were normal in 12 patients with parathyroid mass and 4 patients in the control group. The incidence of PHPT was significantly different between the two groups (P0.05). The incidence of PHPT in patients with urinary calculi 鈮，

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