【摘要】：目的探討ADC值鑒別不同病理學特征直腸腺癌的臨床應用價值。方法回顧性分析48例經(jīng)手術病理證實為直腸腺癌患者的MR資料,測量腫瘤組織的平均ADC值和最小ADC值,并比較不同術后病理學特征(腫瘤分化程度,T分期,T3期固有肌層外浸潤深度,N分期,有無淋巴結(jié)外腫瘤種植,有無脈管癌栓、環(huán)周切緣是否受累)的差異;采用ROC曲線分析評價平均ADC值和最小ADC值對不同病理學特征直腸腺癌的鑒別診斷效能。結(jié)果直腸腺癌平均ADC值和最小ADC值在不同分化程度、T分期、T3期固有肌層外浸潤深度和有無結(jié)外腫瘤種植差異均有統(tǒng)計學意義(P均0.05);最小ADC值在不同環(huán)周切緣狀態(tài)間差異有統(tǒng)計學意義(P=0.035),平均ADC值差異無統(tǒng)計學意義(P=0.180);不同N分期和有無脈管癌栓平均ADC值和最小ADC值差異均無統(tǒng)計學意義(P均0.05)。平均ADC值和最小ADC值鑒別不同分化程度、T3分期、有無結(jié)外種植的直腸腺癌的ROC曲線下面積分別為0.92、0.82、0.79,0.86、0.81、0.74。結(jié)論平均ADC值、最小ADC值有助于鑒別不同病理學特征的直腸腺癌,可為術前直腸腺癌分期及評估預后提供更多的信息。
[Abstract]:Objective to evaluate the clinical value of ADC value in differentiating rectal adenocarcinoma with different pathological features. Methods the MR data of 48 patients with rectal adenocarcinoma proved by operation and pathology were analyzed retrospectively. The mean ADC value and minimum ADC value of tumor tissue were measured. The pathological characteristics of different postoperative patients were compared, such as the degree of differentiation of tumor and T stage, the depth of infiltration of the lamina propria muscularis in T3 stage, whether the tumor was implanted outside the lymph node, whether there was vascular tumor embolus or not, whether the circumferential margin was involved or not. ROC curve analysis was used to evaluate the differential diagnosis efficacy of mean ADC value and minimum ADC value for different pathological features of rectal adenocarcinoma. Results the mean ADC value and minimum ADC value of rectal adenocarcinoma were significantly different in the depth of extramuscular invasion and implantation of extratuberous tumor in T _ 3 stage of T _ 3 stage, and the minimum ADC value was at different circumferential incised margin (P < 0.05). There was significant difference between the two groups (P0. 035), but there was no significant difference in average ADC value (P0. 180), but there was no significant difference in mean ADC value and minimum ADC value in different N stages and with or without vascular tumor thrombus (P0. 05). The mean ADC value and the minimum ADC value were used to differentiate T 3 stage with or without extracolonic implantation. The area under the ROC curve of rectal adenocarcinoma with or without extracolonic implantation was 0.92 0.82 0. 790 鹵0. 86 鹵0. 81 鹵0. 74 respectively. Conclusion the mean ADC value and minimum ADC value are helpful to distinguish rectal adenocarcinoma with different pathological features and provide more information for preoperative staging and prognosis evaluation of rectal adenocarcinoma.
【作者單位】： 復旦大學附屬上海市第五人民醫(yī)院放射科;
【基金】：上海市閔行區(qū)自然科學研究課題(2015MHZ052) 上海市第五人民醫(yī)院科研課題(2011WYYJ05)
【分類號】：R735.37;R445.2

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相關期刊論文 前2條

1 張文娟;蔣健;葉建軍;劉光耀;馬強華;;擴散加權成像ADC值與直腸癌預后因素的相關性研究[J];中國醫(yī)學影像技術;2013年10期

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本文編號：2229338