【摘要】：目的應用動態(tài)對比增強(DCE)-MRI對布氏桿菌性脊柱炎、脊柱結核、脊柱轉移瘤進行定量分析,評估定量DCE-MRI在上述疾病鑒別診斷中的價值。方法收集有完整生化檢驗或手術資料的布氏桿菌性脊柱炎患者30例,男性19例,女性11例,平均年齡50歲;脊柱結核患者30例,男性20例,女性10例,平均年齡44歲;脊柱轉移瘤患者30例,男性16例,女性14例,平均年齡60歲。所有患者均行常規(guī)MRI及DCE-MRI檢查,在灌注參數(shù)圖上測量上述疾病患者病變椎體的容積轉運常數(shù)(K~(trans))、速率常數(shù)(K_(ep))、血管外細胞外容積分數(shù)(V_e)、血漿容積分數(shù)(V_p)值。各指標均呈非正態(tài)分布,以中位數(shù)(M)±四分位數(shù)間距(Q)表示,3種病變各指標的比較均采用秩和檢驗。結果在布氏桿菌性脊柱炎、脊柱結核、脊柱轉移瘤病變椎體中,K~(trans)值分別為(0.716±0.017)、(0.316±0.004)、(0.986±0.012)min~(-1),K_(ep)值分別為(1.326±0.018)、(0.747±0.005)、(2.899±0.054)min~(-1),V_e值分別為0.541±0.011、0.427±0.017、0.338±0.007,V_p值分別為0.034±0.003、0.029±0.003、0.049±0.007,3種病變間差異均有統(tǒng)計學意義(H值分別為50.24、52.49、48.31、46.54,P值均0.01)。結論DCE-MRI定量分析在布氏桿菌性脊柱炎、脊柱結核、脊柱轉移瘤鑒別診斷中具有一定價值。
[Abstract]:Objective to evaluate the value of quantitative DCE-MRI in differential diagnosis of brucellosis spondylitis, spinal tuberculosis and spinal metastases by dynamic contrast enhanced (DCE). Methods A total of 30 patients with brucellosis were collected, including 19 males and 11 females, with an average age of 50 years, and 30 patients with spinal tuberculosis, 20 males and 10 females, with an average age of 44 years. There were 30 patients with spinal metastases, 16 males and 14 females with an average age of 60 years. All the patients were examined by routine MRI and DCE-MRI. The volume transport constant (K ~ (trans), rate constant) (K _ (ep), extracellular volume fraction (ve) and plasma volume fraction (VP) were measured on perfusion parameter map. The mean (M) 鹵quartile interval (Q) was used to show that all the indexes were nonnormal, and the rank sum test was used to compare each index of the three lesions in terms of median (M) 鹵quartile spacing. 緇撴灉鍦ㄥ竷姘忔潌鑿屾，

本文編號：2225431