【摘要】：目的：探討四維左心室容積定量分析工具(4DLVQ)評(píng)價(jià)常規(guī)二維超聲心動(dòng)圖目測(cè)無(wú)室壁運(yùn)動(dòng)異常冠心病患者左室心肌功能的價(jià)值。 方法：62例常規(guī)二維超聲心動(dòng)圖目測(cè)無(wú)室壁運(yùn)動(dòng)異常但經(jīng)冠脈造影證實(shí)冠心病患者(冠心病組)、48例健康志愿者(對(duì)照組)。分別應(yīng)用二維雙平面改良Simpson法測(cè)量左室舒張末期容積、收縮末期容積及射血分?jǐn)?shù)(2D-LVEF),實(shí)時(shí)三平面自動(dòng)化功能成像(AFI)測(cè)量左室長(zhǎng)軸整體徑向峰值應(yīng)變(GLPS),4DLVQ測(cè)量四維左室舒張末期容積、收縮末期容積、左室射血分?jǐn)?shù)(4D-LVEF)及左室收縮末期整體縱向應(yīng)變(GLS)、圓周應(yīng)變(GCS)、面積應(yīng)變(GAS)、徑向應(yīng)變(GRS)。 結(jié)果：1、冠心病組4D-LVEDV較對(duì)照組增大(P0.01),4D-LVEF、GLPS、 GLS、GCS、GAS、GRS均低于對(duì)照組(P0.01)； 2、冠心病組的4D-LVEF與GLPS、GLS、GCS、GAS、GRS有良好相關(guān)性,與GAS的相關(guān)性最高(r=-0.831), GCS、GLS、GRS次之(r=-0.815；r=-0.758; r=0.708),與AFI測(cè)量的GLPS相關(guān)性最低(r=-0.705); 3,4DLVQ測(cè)量的4D-LVEDV、4D-LVESV、4D-LVEF、GLS、GCS、GAS、 GRS均有較好的重復(fù)性。 結(jié)論：4DLVQ測(cè)定左室射血分?jǐn)?shù)及收縮末期心肌應(yīng)變能敏感、準(zhǔn)確地評(píng)價(jià)常規(guī)二維超聲心動(dòng)圖目測(cè)無(wú)室壁運(yùn)動(dòng)異常冠心病患者左室心肌功能變化,四維應(yīng)變中尤以面積應(yīng)變最佳。
[Abstract]:Objective: to evaluate the value of four dimensional quantitative analysis of left ventricular volume (4DLVQ) in evaluating left ventricular myocardial function in patients with coronary heart disease without ventricular wall motion abnormality by conventional two-dimensional echocardiography. Methods Sixty-two cases of coronary heart disease (CHD group) with coronary artery disease (CHD) confirmed by coronary angiography (CHD group) were examined by routine two-dimensional echocardiography in 48 healthy volunteers (control group). The left ventricular end-diastolic volume, end-systolic volume and ejection fraction (2D-LVEF) were measured by two-dimensional biplane modified Simpson method, respectively. The left ventricular end-diastolic volume was measured by real-time three-plane automatic functional imaging (AFI). The global radial peak strain of left ventricular long axis was measured by (GLPS) 4DLVQ, and the left ventricular end-diastolic volume was measured by four-dimensional left ventricular end-diastolic volume (4DLVQ). End systolic volume, left ventricular ejection fraction (4D-LVEF) and left ventricular end systolic global longitudinal strain (GLS), circumferential strain (GCS), area strain (GAS), radial strain (GRS). Results the 4D-LVEDV of the coronary heart disease group was significantly higher than that of the control group (P0.01), and the GRS of the GAS-GAS-GASS of the coronary heart disease group was lower than that of the control group (P0.01), while the 4D-LVEF of the coronary heart disease group had a good correlation with the GLPS-GLSS-GAS-GAS-GRS, the highest correlation was with the GAS (r-0.831), the second was the GLSS-GRS (r-0.815). The correlation with GLPS measured by AFI was the lowest (r-0.705), and 4D-LVEDVV with 4D-LVESVV (4D-LVEF / GLSS-GCSGAS-GAS-GRS) by 3DLVQ was better than that measured by AFI (r = 0.758; r = 0.708, r = -0.758, r = 0.708, r = -0.758). Conclusion the measurement of left ventricular ejection fraction (LVEF) and end-systolic myocardial strain by W4DLVQ is sensitive. Conventional two-dimensional echocardiography can accurately evaluate the changes of left ventricular myocardial function in patients with coronary heart disease without abnormal ventricular wall motion. The area strain is the best in four-dimensional strain.
【學(xué)位授予單位】：廣西醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R541.4;R540.45

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