超聲診斷男性乳腺發(fā)育癥及其某些發(fā)病規(guī)律探討
發(fā)布時(shí)間：2018-07-31 06:32
【摘要】：研究背景及目的： 近年來女性乳腺疾病越來越多地得到了大家的重視,隨著健康知識(shí)的普及、保健意識(shí)的增強(qiáng),女性乳腺癌的防治工作得到了廣泛的關(guān)注；相比較而言,男性乳腺疾病卻往往容易忽視,其中男性乳腺發(fā)育癥是最為常見的男性乳腺疾病。 男性乳腺發(fā)育癥是指男性乳腺腺體組織良性增厚、呈婦乳樣改變,可發(fā)生于任何年齡。據(jù)流行病學(xué)報(bào)道,其流行率在國外男性人群可達(dá)32%-65%。超聲診斷男性乳腺發(fā)育癥的回顧性總結(jié)和前瞻性研究在國內(nèi)開展得比較少,國外的相關(guān)文獻(xiàn)比較零散,且國內(nèi)男性與西方白色人種男性患乳腺疾病或許存在差異,我們亦需要國人自己的數(shù)據(jù)。 本研究目的在探討超聲診斷、隨訪監(jiān)測男性乳腺發(fā)育癥的重要臨床價(jià)值,并分析通過超聲診斷的男性乳腺發(fā)育癥資料,發(fā)現(xiàn)并探討其患病年齡、檢查年份及單雙側(cè)分布等相關(guān)發(fā)病規(guī)律。 方法： 選擇在我院2005年1月-2013年12月接受乳腺超聲檢查的178例男性患者,年齡3-98歲,平均36.8+21.7歲；其中超聲診斷為男性乳腺發(fā)育癥145例,年齡3-98歲,平均35.8±21.1歲。分析并總結(jié)經(jīng)病理證實(shí)或臨床確診的145例男性乳腺發(fā)育的超聲聲像圖特異性表現(xiàn),并將超聲診斷與病理及隨訪結(jié)果對照。 將所有資料的基本情況、超聲檢查所見與結(jié)果輸入計(jì)算機(jī)excel文件,整理分組進(jìn)行統(tǒng)計(jì)。所有男性乳腺發(fā)育患者根據(jù)年齡分≤19歲、20-39歲、40-59歲、60-79歲、≥80歲5組；≤30歲和30歲兩組；20-39歲和非此年齡段兩組；根據(jù)檢查年份分2005年、2006年、2007年、2008年、2009年、2010年、2011年、2012年、2013年共9組。采用SPSS19.0統(tǒng)計(jì)軟件進(jìn)行分析。采用矛檢驗(yàn)分析患者在不同年齡組、不同檢查年份的分布情況,以P0.05為差異有統(tǒng)計(jì)學(xué)意義。用統(tǒng)計(jì)學(xué)頻數(shù)分布圖觀察檢查者單雙側(cè)患病分布情況。 結(jié)果： 本組145例男性乳腺發(fā)育癥患者中,95例為單側(cè)(95/145,65.52%),其中左側(cè)乳腺發(fā)育57例,右側(cè)38例；50例為雙側(cè)(其中1例為左側(cè)病變發(fā)展至雙側(cè)),超聲聲像圖均顯示為不同程度的乳腺腺體增厚,長徑約2.1～6.6cm,平均長徑3.38+0.92cm；厚約0.50～2.90cm,平均0.78+0.30cm。 男性乳腺發(fā)育癥超聲聲像圖特點(diǎn)：乳頭下方、乳暈周圍可見增厚的乳腺腺體組織回聲,可呈低回聲或稍高回聲或蜂窩狀回聲,邊界尚清,無包膜,與前方皮下脂肪組織及后方胸大肌分界可見,內(nèi)部回聲尚均勻或欠均勻,無明顯強(qiáng)回聲鈣化灶。彩色多普勒血流顯像(CDFI)顯示：腺體內(nèi)及周邊血流信號(hào)不豐富。結(jié)論： 本研究通過分析145例男性乳腺發(fā)育癥的超聲聲像圖特點(diǎn),對照病理及隨訪結(jié)果,并統(tǒng)計(jì)學(xué)分析其患病年齡、檢查年份、單雙側(cè)的分布,結(jié)論如下： 1.超聲可診斷和鑒別診斷男性乳腺發(fā)育癥,是首選檢查方法。 2.超聲具有隨訪和評價(jià)男性乳腺發(fā)育治療效果的優(yōu)勢。 3.本組研究首次發(fā)現(xiàn)男性乳腺發(fā)育癥患者多發(fā)于20～39歲年齡段。 4.本組研究首次發(fā)現(xiàn)近年來男性乳腺發(fā)育癥患病呈增長趨勢,于2013年最多。 5.本組研究單側(cè)乳腺發(fā)育最常見(95/145,65.52%)。
[Abstract]:Research background and purpose:
In recent years, women's breast disease has been paid more and more attention. With the popularization of health knowledge and the enhancement of health awareness, the prevention and treatment of female breast cancer has been widely paid attention. In comparison, male breast disease is often ignored, and male mammary gland development is the most common male breast disease.
Male mammary gland development refers to the benign thickening of the gland tissue of the male mammary gland, which can occur at any age. According to the epidemiological report, the prevalence rate in the male population of foreign men can reach 32%-65%. ultrasonography in the diagnosis of male mammary gland development. More scattered, and there may be differences in breast disease between domestic and western white men, we need our own data.
The purpose of this study is to explore the important clinical value of ultrasound diagnosis and follow-up monitoring of male mammary gland development, and to explore and explore the age of the disease, the year and the distribution of single side and bilateral distribution, and to analyze the data of male mammary gland development by ultrasound.
Method:
178 male patients, aged 3-98 years and 36.8+21.7 years old, were selected in our hospital in January 2005 -2013 December. Among them, 145 cases of male mammary gland development, 3-98 years old and average 35.8 + 21.1 years old, were diagnosed by ultrasound. The ultrasonographic features of 145 male mammary gland development confirmed by pathology or clinical diagnosis were analyzed and summarized. The ultrasonographic diagnosis was compared with pathology and follow-up results.
The basic situation of all the data, the ultrasound examination and the results entered the computer excel file, sorting out the statistics. All male breast development patients according to the age of 19 years, 20-39 years old, 40-59, 60-79, 80 years of 5 groups; less than 30 years and 30 years of two groups; 20-39 years and non age group two; according to the year of examination, 2006, 2006, 2005, 2006. In 2007, 2008, 2008, 2009, 2010, 2011, 2012, and 2013, the 9 groups were analyzed with SPSS19.0 software. The distribution of patients in different age groups and different examination years was analyzed by spear test. The difference was statistically significant with the difference of P0.05.
Result:
Of the 145 male patients with mammary gland development, 95 were unilateral (95/145,65.52%), of which 57 were developed in the left side of the breast, 38 in the right, and 50 in the bilateral (1 of the left lesions developed to bilateral). The ultrasonographic map showed the thickening of the glands of the breast in varying degrees, the length of the diameter of about 2.1 to 6.6cm, the average length of 3.38+0.92cm, and the thickness of about 0.50 to 2.90. Cm, average 0.78+0.30cm.
Characteristics of ultrasonic image of male mammary gland development: below the nipple, the echo of thickened mammary gland tissue around the corola can be seen around the mammary gland. It can be hypoechoic or slightly hyperechoic or honeycomb echo, the boundary is clear, no capsule, and the boundary between the anterior subcutaneous adipose tissue and the posterior pectoralis major muscle is visible, the internal echo is even or less homogeneous, and there is no obvious echo calcification. Color Doppler flow imaging (CDFI) showed that the blood flow signals in and around the glands were not abundant.
In this study, we analyzed the ultrasonographic features of 145 cases of male mammary gland development, compared the pathological and follow-up results, and analyzed the age of the disease, examined the year, and the distribution of the single bilateral. The conclusions are as follows:
1. ultrasound is the first choice for the diagnosis and differential diagnosis of gynecomastia.
2. ultrasound has the advantage of follow-up and evaluation of male breast development.
3. for the first time, male patients with breast development were found in the age group of 20~39.
4. the first study found that the incidence of gynecomastia increased in recent years, the most in 2013.
5. in this group, unilateral breast development is the most common (95/145,65.52%).
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R655.8;R445.1
本文編號(hào)：2154732
[Abstract]:Research background and purpose:
In recent years, women's breast disease has been paid more and more attention. With the popularization of health knowledge and the enhancement of health awareness, the prevention and treatment of female breast cancer has been widely paid attention. In comparison, male breast disease is often ignored, and male mammary gland development is the most common male breast disease.
Male mammary gland development refers to the benign thickening of the gland tissue of the male mammary gland, which can occur at any age. According to the epidemiological report, the prevalence rate in the male population of foreign men can reach 32%-65%. ultrasonography in the diagnosis of male mammary gland development. More scattered, and there may be differences in breast disease between domestic and western white men, we need our own data.
The purpose of this study is to explore the important clinical value of ultrasound diagnosis and follow-up monitoring of male mammary gland development, and to explore and explore the age of the disease, the year and the distribution of single side and bilateral distribution, and to analyze the data of male mammary gland development by ultrasound.
Method:
178 male patients, aged 3-98 years and 36.8+21.7 years old, were selected in our hospital in January 2005 -2013 December. Among them, 145 cases of male mammary gland development, 3-98 years old and average 35.8 + 21.1 years old, were diagnosed by ultrasound. The ultrasonographic features of 145 male mammary gland development confirmed by pathology or clinical diagnosis were analyzed and summarized. The ultrasonographic diagnosis was compared with pathology and follow-up results.
The basic situation of all the data, the ultrasound examination and the results entered the computer excel file, sorting out the statistics. All male breast development patients according to the age of 19 years, 20-39 years old, 40-59, 60-79, 80 years of 5 groups; less than 30 years and 30 years of two groups; 20-39 years and non age group two; according to the year of examination, 2006, 2006, 2005, 2006. In 2007, 2008, 2008, 2009, 2010, 2011, 2012, and 2013, the 9 groups were analyzed with SPSS19.0 software. The distribution of patients in different age groups and different examination years was analyzed by spear test. The difference was statistically significant with the difference of P0.05.
Result:
Of the 145 male patients with mammary gland development, 95 were unilateral (95/145,65.52%), of which 57 were developed in the left side of the breast, 38 in the right, and 50 in the bilateral (1 of the left lesions developed to bilateral). The ultrasonographic map showed the thickening of the glands of the breast in varying degrees, the length of the diameter of about 2.1 to 6.6cm, the average length of 3.38+0.92cm, and the thickness of about 0.50 to 2.90. Cm, average 0.78+0.30cm.
Characteristics of ultrasonic image of male mammary gland development: below the nipple, the echo of thickened mammary gland tissue around the corola can be seen around the mammary gland. It can be hypoechoic or slightly hyperechoic or honeycomb echo, the boundary is clear, no capsule, and the boundary between the anterior subcutaneous adipose tissue and the posterior pectoralis major muscle is visible, the internal echo is even or less homogeneous, and there is no obvious echo calcification. Color Doppler flow imaging (CDFI) showed that the blood flow signals in and around the glands were not abundant.
In this study, we analyzed the ultrasonographic features of 145 cases of male mammary gland development, compared the pathological and follow-up results, and analyzed the age of the disease, examined the year, and the distribution of the single bilateral. The conclusions are as follows:
1. ultrasound is the first choice for the diagnosis and differential diagnosis of gynecomastia.
2. ultrasound has the advantage of follow-up and evaluation of male breast development.
3. for the first time, male patients with breast development were found in the age group of 20~39.
4. the first study found that the incidence of gynecomastia increased in recent years, the most in 2013.
5. in this group, unilateral breast development is the most common (95/145,65.52%).
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R655.8;R445.1
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