本文選題：冠心病 + 經(jīng)皮冠狀動脈介入術(shù)��； 參考：《東南大學(xué)學(xué)報(醫(yī)學(xué)版)》2017年05期

【摘要】：目的:探討四維應(yīng)變成像(four-dimensional strain imaging,4D-SI)技術(shù)預(yù)測經(jīng)皮冠狀動脈介入(percutaneous coronary intervention,PCI)術(shù)冠心病患者左心功能改善的臨床價值。方法:選取經(jīng)冠脈造影診斷為冠心病且成功進(jìn)行PCI術(shù)的患者55例,以PCI術(shù)后6個月較術(shù)前左室射血分?jǐn)?shù)(left ventricular ejection fraction,LVEF)改善(ΔLVEF)≥5%將冠心病患者分為左心功能改善組(A組)和未改善組(B組)。分別于PCI術(shù)前及術(shù)后6個月對各組患者進(jìn)行常規(guī)超聲心動圖檢查,測量左室舒張末期容積(left ventricular end-diastolic volume,LVEDV)、左室收縮末期容積(left ventricular end-systolic volume,LVESV)、LVEF;應(yīng)用自動功能成像(automated function imaging,AFI)技術(shù)測量二維整體峰值縱向應(yīng)變(two-dimensional global longitudinal peak strain,2D-GLPS);并應(yīng)用4D-SI技術(shù)測得四維整體峰值長軸應(yīng)變(global longitudinal peak strain,4DGLPS)、環(huán)向應(yīng)變(global circumferential peak strain 4D-GCPS)、面積應(yīng)變(global area peak strain,4D-GAPS)及徑向應(yīng)變(global radial peak strain,4D-GRPS)參數(shù)指標(biāo)。結(jié)果:A組PCI術(shù)前及術(shù)后6個月2D-GLPS、4DGLPS、4D-GCPS、4D-GAPS和4D-GRPS均明顯高于B組(P0.05)。單參數(shù)受試者工作特征曲線(ROC曲線)分析結(jié)果顯示4D-GLPS的曲線下面積(AUC)較大,為0.944,靈敏度及特異度較高,分別為91.3%、93.8%,截斷值為-16.5%;在多參數(shù)聯(lián)合分析中,四維應(yīng)變參數(shù)聯(lián)合二維應(yīng)變參數(shù)的AUC較大,為0.969,靈敏度及特異度較高,分別為95.7%、90.6%。結(jié)論:4D-SI技術(shù)能更準(zhǔn)確預(yù)測冠心病患者PCI術(shù)后左室心肌功能的改善,其中4D-GAPS及4D-GCPS能夠作為術(shù)后左心整體功能改善的獨立預(yù)測指標(biāo)。
[Abstract]:Objective: to evaluate the clinical value of four-dimensional strain imaging technique in predicting the improvement of left ventricular function in patients with coronary heart disease after percutaneous coronary intervention. Methods: 55 patients with coronary artery disease diagnosed by coronary angiography and successfully underwent PCI were selected. Patients with coronary heart disease were divided into two groups: left ventricular ejection fraction (left ventricular ejection fractionation) improvement (螖 LVEF 鈮，

本文編號：2035659