本文選題：Gd-EOB-DTPA + 擴(kuò)散加權(quán)成像��； 參考：《第三軍醫(yī)大學(xué)學(xué)報(bào)》2015年06期

【摘要】：目的在常規(guī)動(dòng)態(tài)對(duì)比增強(qiáng)MRI的基礎(chǔ)上,探討Gd-EOB-DTPA增強(qiáng)MR掃描肝膽期結(jié)合擴(kuò)散加權(quán)成像序列(DW-MRI)診斷原發(fā)性肝細(xì)胞癌的價(jià)值。方法回顧性分析60例懷疑原發(fā)性肝細(xì)胞癌(hepatocellular carcinoma,HCC)患者的Gd-EOB-DTPA增強(qiáng)MR掃描動(dòng)脈期、門脈期、肝膽期及DWI圖像資料。分為3組進(jìn)行閱讀和比較,分析影像特征,獲得最終影像診斷結(jié)果。以手術(shù)病理為標(biāo)準(zhǔn),采用受試者工作特征曲線(ROC)曲線下面積(AUC)分析Gd-EOB-DTPA肝膽期結(jié)合DWI序列對(duì)HCC的診斷價(jià)值。結(jié)果 60例患者共發(fā)現(xiàn)肝內(nèi)病灶80個(gè),其中40例患者共診斷56個(gè)HCC,其中22個(gè)直徑≤2 cm。在常規(guī)動(dòng)態(tài)對(duì)比增強(qiáng)MR掃描基礎(chǔ)上,結(jié)合Gd-EOB-DTPA肝膽期及DW-MRI不能增加對(duì)所有大小的HCC的診斷準(zhǔn)確性,但對(duì)直徑≤2 cm的早期HCC的準(zhǔn)確性最高(P=0.024 8),且當(dāng)僅結(jié)合Gd-EOB-DTPA增強(qiáng)MR掃描肝膽期時(shí),其診斷準(zhǔn)確性亦高于常規(guī)對(duì)比動(dòng)態(tài)增強(qiáng)掃描(P=0.043 2),具統(tǒng)計(jì)學(xué)意義。結(jié)論在常規(guī)動(dòng)態(tài)對(duì)比增強(qiáng)MR基礎(chǔ)上,結(jié)合Gd-EOB-DTPA增強(qiáng)肝膽期圖像和DWI序列有助于診斷直徑≤2 cm的早期HCC,可以作為常規(guī)MR序列的有效補(bǔ)充。
[Abstract]:Objective to evaluate the diagnostic value of conventional dynamic contrast enhanced MRI (DW-MRI) in the diagnosis of primary hepatocellular carcinoma (HCC) by contrast-enhanced Mr imaging (Mr) combined with diffusion weighted imaging (DW-MRI). Methods the images of arterial phase, portal phase, hepatobiliary phase and DWI in 60 patients with suspected hepatocellular carcinoma (HCC) were analyzed retrospectively. Three groups were divided into three groups to read and compare, analyze the image features, and obtain the final image diagnosis results. The diagnostic value of Gd-EOB-DTPA hepatobiliary phase combined with DWI sequence in HCC was analyzed by using the area under the operating characteristic curve (ROC) curve of the subjects according to the criteria of operation and pathology. Results A total of 80 intrahepatic lesions were found in 60 patients, of which 56 HCC were diagnosed in 40 of them, 22 of which were less than 2 cm in diameter. On the basis of conventional dynamic contrast-enhanced Mr scanning, combining with Gd-EOB-DTPA hepatobiliary phase and DW-MRI could not increase the diagnostic accuracy of HCC of all sizes, but the accuracy was the highest for early HCC with diameter 鈮，

本文編號(hào)：1900545