基于有限元分析的超聲彈性成像技術(shù)的研究
發(fā)布時間:2018-05-14 20:28
本文選題:超聲彈性成像 + Comsol; 參考:《西安電子科技大學》2014年碩士論文
【摘要】:生物組織的彈性信息可以反映組織病變與否及病變程度,然而傳統(tǒng)醫(yī)學成像方法卻不能直接反應(yīng)組織的彈性信息。20世紀90年代初由日本學者Y.Yamakoshi與美國學者J.Ophir首先提出一種新的超聲成像技術(shù)——超聲彈性成像,其實質(zhì)是超聲組織定征技術(shù)的進一步拓展。超聲組織定征技術(shù)是研究多種與生物組織的生理病理狀態(tài)和組織結(jié)構(gòu)相聯(lián)系的超聲學參量技術(shù),其最終目的是判斷生物組織的病理狀態(tài)。 超聲彈性成像的基本原理是:將外加激勵源作用于軟組織上,組織受壓后內(nèi)部的彈性差異將會導(dǎo)致不同的響應(yīng),該響應(yīng)包括組織受壓位移形變大小、組織所受應(yīng)力大小以及應(yīng)變大小均有不同。 本文以彈性力學為基礎(chǔ),利用有限元方法進行組織應(yīng)變、應(yīng)力的仿真分析研究。有限元分析采用低頻聲壓為外加激勵源,這樣不僅可以改變組織的壓縮量還保證在實驗進行中組織的內(nèi)部結(jié)構(gòu)關(guān)系滿足單純的線彈性假設(shè)。對待研究組織利用Comsol和Field II軟件進行模擬分析,獲得組織的位移、應(yīng)變以及應(yīng)變的分布,為后續(xù)進行的超聲彈性成像提供了重要的實驗依據(jù)。論文提出利用Hermite插值方式對互相關(guān)函數(shù)進行插值算法,與常用的拋物線插值方式相比,提出的方法更能有效計算組織應(yīng)變響應(yīng)。
[Abstract]:The elastic information of biological tissue can reflect whether or not the tissue changes and the extent of the lesions. However, traditional medical imaging methods can not directly respond to the elastic information of tissue. In the early 1990s, a new ultrasonic imaging technique, called ultrasonic elastic imaging, was first proposed by Japanese scholar Y.Yamakoshi and American scholar J.Ophir. Its essence is the further development of ultrasonic tissue characterization technology. Ultrasonic tissue characterization is a kind of ultrasonic parameter technique which is related to the physiological and pathological state and structure of biological tissue. The ultimate purpose of ultrasonic tissue identification is to judge the pathological state of biological tissue. The basic principle of ultrasonic elastic imaging is that when the external excitation source is applied to the soft tissue, the elastic difference within the tissue after compression will lead to different responses, which include the deformation of the tissue under compression. The stress and strain of the tissue are different. In this paper, based on the elastic mechanics, the finite element method is used to simulate the microstructure strain and stress. In the finite element analysis, the low frequency sound pressure is used as the external excitation source, which can not only change the compression of the structure, but also ensure that the internal structure of the structure can satisfy the simple linear elastic hypothesis in the experiment. Comsol and Field II software are used to simulate and analyze the research tissue, and the displacement, strain and strain distribution of the tissue are obtained, which provides an important experimental basis for the subsequent ultrasonic elastic imaging. In this paper, the Hermite interpolation method is proposed to interpolate the cross-correlation function. Compared with the parabolic interpolation method, the proposed method is more effective in calculating the strain response of tissue.
【學位授予單位】:西安電子科技大學
【學位級別】:碩士
【學位授予年份】:2014
【分類號】:R445.1
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