本文選題：頸動脈彈性 + 高血壓��； 參考：《中華高血壓雜志》2015年12期

【摘要】：目的應用超聲二維應變成像技術評價高血壓患者的頸動脈血管彈性。方法選取2012年1月至12月在天津醫(yī)科大學第二醫(yī)院心內(nèi)科住院的高血壓患者120例(1、2和3級高血壓組)和正常血壓及正常高值血壓者40人(對照組)。所有入選對象均行心臟超聲檢查及頸動脈彩色多普勒超聲心動圖(彩超)檢查,應用二維應變成像技術測量頸動脈短軸方向收縮期峰值整體圓周應變、收縮早期整體圓周應變率(CSr)、收縮晚期整體CSr絕對值,計算僵硬系數(shù)(β1和β2)。結果隨著血壓升高,室間隔厚度(IVST)[(8.2±1.4)、(9.1±1.1)、(9.4±1.4)、(11.2±2.2)mm]、左心室后壁厚度(LVPWT)[(8.5±1.1)、(8.6±1.0)、(9.2±1.4)、(10.7±2.2)mm]、左心室質(zhì)量指數(shù)(LVMI)[(53.3±10.8)、(59.6±15.8)、(60.2±10.1)、(76.4±26.2)g/m2]、β2[(0.6±0.1)、(0.8±0.2)、(0.9±0.2)、(1.1±0.2)]逐漸升高;而收縮期峰值整體圓周應變[(6.0±0.7)%、(5.4±0.1)%、(5.0±0.3)%、(4.7±0.4)%]、收縮早期整體CSr(×10)[(7.1±0.8)/s、(6.3±0.6)/s、(5.5±0.5)/s、(5.1±0.5)/s]降低(均P0.05)。相關性分析顯示,LVMI與收縮期峰值整體圓周應變、收縮早期整體CSr和收縮晚期整體CSr絕對值呈負相關;與β2呈正相關。結論高血壓患者收縮期整體圓周應變、收縮早期整體CSr隨血壓水平增高而減小,β2隨著血壓水平的增高增大,提示隨著血壓增高頸動脈僵硬度增加,超聲二維應變成像技術可作為一項診斷血管彈性病變的新技術。
[Abstract]:Objective to evaluate carotid artery elasticity in patients with hypertension by two-dimensional strain imaging. Methods from January to December, 2012, 120 patients with hypertension in Department of Cardiology, second Hospital of Tianjin Medical University, and 40 patients with normal blood pressure and normal high blood pressure (control group) were selected. All subjects were examined by echocardiography and color Doppler echocardiography (CDFI) of carotid artery. Two-dimensional strain imaging technique was used to measure the global circumferential strain of peak systolic peak in short axis of carotid artery. The stiffness coefficients (尾 _ 1 and 尾 _ 2) were calculated by the whole circumferential strain rate (CSR) in the early stage of contraction and the absolute value of global CSr in the late stage of contraction. 緇撴灉闅忕潃琛，

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