本文選題：超聲特征 + 分化型甲狀腺癌��； 參考：《中國超聲醫(yī)學雜志》2017年10期

【摘要】：目的探討分化型甲狀腺癌(DTC)與結(jié)節(jié)性甲狀腺腫(NG)在相關(guān)實驗室檢查指標(TSH、TG、TGAb、TPOAb)及超聲影像特征方面的差異。方法回顧性分析在我院行甲狀腺部分或全部切除術(shù),且術(shù)后病理證實為DTC或NG的354例患者術(shù)前超聲檢查圖像特征及TSH、TG、TGAb、TPOAb水平,并進行多因素分析,繪制ROC曲線,評價其在DTC和NG鑒別診斷中的意義。結(jié)果多因素分析結(jié)果顯示DTC組TSH、TG、TGAb、TPOAb水平高于NG組;DTC組內(nèi)縱橫比≥1、有微小鈣化、邊緣不規(guī)整、形態(tài)不規(guī)則、極低回聲、內(nèi)部結(jié)構(gòu)為實性、結(jié)節(jié)為單發(fā)的比例高于NG組,均有統(tǒng)計學差異。兩組在結(jié)節(jié)大小、實質(zhì)回聲不均勻性、結(jié)節(jié)內(nèi)血流方面無統(tǒng)計學差異。繪制結(jié)節(jié)數(shù)目、TSH、縱橫比、形態(tài)、邊緣、綜合指標的ROC曲線,形態(tài)、邊緣、綜合指標ROC曲線下面積分別為0.80、0.85、0.96,有很好診斷價值。結(jié)論 TSH、TG、TGAb、TPOAb水平升高,縱橫比≥1、有微小鈣化、邊緣不規(guī)整、形態(tài)不規(guī)則、極低回聲、內(nèi)部結(jié)構(gòu)為實性,結(jié)節(jié)為單發(fā)是DTC的危險因素。結(jié)節(jié)數(shù)目、TSH、縱橫比、形態(tài)、邊緣聯(lián)合形成綜合指標對于鑒別DTC和NG具有很高的診斷價值。
[Abstract]:Objective to investigate the difference between differentiated thyroid carcinoma (DTC) and nodular goiter (NGN) in laboratory examination of TSHT TGAbTGAbTPOAband the characteristics of ultrasound. Methods the ultrasonographic features and the level of TGAb-TPOAb were analyzed retrospectively in 354 patients who underwent partial or total thyroidectomy in our hospital and proved to be DTC or NG by pathology. The ROC curves were plotted by multivariate analysis. To evaluate its significance in differential diagnosis of DTC and NG. Results the results of multivariate analysis showed that the level of TSH TGG Ab in DTC group was higher than that in NG group (P > 1), with slight calcification, irregular margin, irregular shape, very low echo, solid internal structure, and higher incidence of single nodules than those in NG group. There was statistical difference between the two groups. There were no significant differences in nodule size, parenchymal echo heterogeneity and blood flow within the nodules between the two groups. The ROC curve, shape, edge and ROC curve of the number of nodules, aspect ratio, shape, edge and synthetic index were drawn, and the area under the ROC curve was 0.80 and 0.850.96, respectively, which had very good diagnostic value. Conclusion the level of TGAb-TPOAb is increased, the aspect ratio 鈮，

本文編號：1856066